Liver Zones Flashcards
1
Q
Zone I
A
Periportal (near portal vein)
Affected first by viral hepatitis
Ingested toxins (ex - cocaine)
Think - things that go thru GI blood get here first
2
Q
Zone II
A
Intermediate
Yellow Fever (II - like yeLLow)
3
Q
Zone III
A
Pericentral vein or centrilobular
Affected first by ischemia
Contain cytochrome P450 system
Most sensitive to metabolic toxins
Site of alcohol hepatitis
Think - all detox related
