Branchial Apparatus Flashcards
Clefts v Pouches v Arches
Clefts - from ectoderm
Arches - mesoderm and neural crest cells
Pouches - endoderm
CAP from out to in
Branchial Cleft Derivatives
1- external auditory meatus
2-4 cervical sinuses eventually obliterated but if persist form cysts that are NOT mobile when swallowing
1st Arch
Maxillary process- maxilla and zygomatic bone
Mandibular process - Meckel cartilage –> mandible, malleus, incus, sphenomandibular ligament
Muscles of mastication, mylohyoid, anterior belly of digastric, tensor tympani, anterior 2/3 tongue
CN V2 and V3
2nd Arch
Reichert cartilage - stapes, styloid process, lesser horn of hyoid, styloid ligament
Muscles of facial expression, stapedius, stylohyoid, posterior belly of digastric
CN VII
3rd Arch
Greater horn of hyoid
Stylopharyngeus
CN IX
4-6th Arches
Arytenoids, cricoid, corniculate, cuneiform, thyroid cartilage
4- pharyngeal constrictors, crycothyroid, levator veli palatini (CN X - superior laryngeal branch)
6- all intrinsic muscles of larynx except cricothyroid (CN X - recurrent laryngeal branch)
1st Pouch
Middle ear cavity, Eustachian tube, mastoid air cells
2nd Pouch
Epithelial lining of palatine tonsils
3rd Pouch
Dorsal wings become inferior parathyroids
Ventral wings become thymus
4th Pouch
Dorsal wings become superior parathyroids
Ventral wings become parafollicular C cells of thyroid
Pierre Robin Sequence
1st and 2nd Arch problem
Micrognathia, glossoptosis, cleft palate, airway obstruction
Treacher Collins Syndrome
1st and 2nd Arch problem
Neural crest cell problem leading to mandibular hypoplasia, facial abnormalities