Immune Cell Surface Proteins Flashcards
1
Q
All T cells
A
TCR (binds MHC)
CD3 (associated w. TCR signal transduction)
CD28 (co-act - binds B7 of APC)
CXCR4/CCR5 (co-receptor for HIV)
2
Q
Specific to CD4+
A
CD40L (binds CD40 on B cells then release cytokines for class switching)
3
Q
Regulatory T Cells
A
CD4+
CD25+
4
Q
B Cells
A
Ig (bind antigen) - IgM and IdD prior to activation
CD19, CD20, CD21 (receptor for EBV - “bar”), CD40 (to bind CD4+)
MHC II and B7 (as an APC)
5
Q
Macrophages
A
CD14 (binds PAMPs)
CD40 (bind CD4+ cells)
CCR5
MHC II and B7 (APC)
Fc and C3b receptors (for enhanced phagocytosis)
6
Q
NK Cells
A
CD56
7
Q
Heme Stem Cells
A
CD34
8
Q
Reed Sternberg Cells
A
CD15+ and CD30+
