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Step 1 Memorization Hour > Serum Auto-Antibodies > Flashcards

Serum Auto-Antibodies Flashcards

1
Q

Anti-Ach

A

Myasthenia Gravis

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2
Q

Anti-glomerular basement membrane

A

Good Pasture’s Syndrome

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3
Q

Anti-Beta2 Glycoprotein

A

Antiphospholipid syndrome

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4
Q

Anti-cardiolipin

A

SLE, anti-phospholipid syndrome “lupus anti-coagulant”)

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5
Q

Anti-centromere

A

CREST

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6
Q

Anti-desmoglein

A

Pemphigus Vulgaris

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7
Q

Anti-glutamic acid decarboxylase

A

Type 1 DM

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8
Q

Islet Cell Cytoplasmic Antibodies

A

Type 1 DM

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9
Q

Anti-hemidesmosomes

A

Bullous Pemphigoid

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10
Q

Anti-synthetase (Anti-Jo1), Anti-SRP, Anti-helicase

A

Polymyositis, dermatomyositis

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11
Q

Anti-microsomal, Anti-thyroid peroxidase, Anti-thyroglobulin

A

Hashimoto

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12
Q

Anti-mitochondrial

A

AMA

Primary biliary cirrhosis

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13
Q

Anti-parietal Cell or Anti-intrinsic factor

A

pernicious anemia

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14
Q

Antiphospholipase A2 receptor

A

Primary Membranous Nephropathy

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15
Q

Anti-Scl-70

A

AKA anti-DNAtopoisomerase I

Scleroderma

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16
Q

Anti-Smooth Muscle

A

Autoimmune hepatitis Type 1

17
Q

Anti-SSA, Anti-SSB

A

AKA Anti-Ro and Anti-La

Sjogren Syndrome

18
Q

Anti-TSH receptor

A

Graves Disease

19
Q

Anti-presynaptic Ca Channel

A

Lambert Eaton

20
Q

IgA Anti-tissue transglutaminase

21
Q

p-ANCA

A

Churg Strauss (asthma, granulomas, eosinophils)

UC

Microscopic polyangitis

22
Q

c-ANCA

A

Wegeners (AKA granulomastosis w/ polyangitis)

23
Q

Rheumatoid factor

A

IgM against IgG Fc region

non-specific for rheumatoid arthritis

24
Q

Anti-CCP

A

More specific for rheumatoid arthritis

25
Q

ANA

A
  • Anti-nuclear antibody

- Non-specific screening for SLE

26
Q

Anti-dsDNA and Anti-Smith

27
Q

Anti-histone

A

Drug-induced lupus

28
Q

Anti-U1 RNP

A

RNP = ribonucleoprotein

Mixed connective tissue disease

Step 1 Memorization Hour (127 decks)

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