Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Host and Defense 2020 > 4/7/17 The Immune response in Time and Space GERMAN TEST #3 > Flashcards

4/7/17 The Immune response in Time and Space GERMAN TEST #3 Flashcards

1
Q

What part of the immune response deals with activating macrophages and dendritic cells?

A

-Induced innate response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What part of the immune response deals with B and T cell activation and differentiation?

A

-Adaptive immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What part of the immune response deals with antibody production by plasma cells?

A

-Adaptive immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What part of the immune response deals with acute phase and interferon response?

A

-Induced innate response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What part of the immune response deals with CD8 T cell cytotoxicity?

A

-Adaptive immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What part of the immune response deals with Neutrophil infiltration?

A

-Induced innate response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What part of the immune response deals with NK cell response?

A

-Induced Innate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What part of the immune response deals with complement?

A

-Immediate innate response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What part of the immune response deals with Antimicrobial peptides?

A

-Immediate inate response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where is complement produced?

A

-Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the name of the phase when the liver makes complement?

A

-Acute phase response driven by IL-6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What type of cell do you normally find in intraepithelial lymphocytes?

A

-Gamma:Delta T cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What induced the epithelial tissue to release alpha or beta defensins?

A

-Th17 cells via cytokines IL-22 and IL-17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What type of peptides are lysozymes, lactoferrins, and defensins?

A

-Antimicrobial peptides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What releases antimicrobial peptides?

A

-Barriers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Where do most of the innate immune cells reach maturity at?

A

-Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What do NK cells get educated to do?

A

-Recognize MHC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

If there is no MHC present on the cell an NK cell finds what happens to that cell?

A

-It is killed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How long does it take for a single lymphocyte to circulate through the body?

A

-24 hours

20
Q

Where are most infections stopped?

A
  • Epithelial

- Mucosal Surfaces

21
Q

T/F mucosal cells recruit neutrophils immediately for an infection

A

False

-They do not recruit neutrophils

22
Q

What does an exudate contain?

A
  • Complement

- Antimicrobial proteins

23
Q

What pro-inflammatory cytokines activates vascular endothelium and activates lymphocytes?

A

-IL-1B

24
Q

What pro-inflammatory cytokine activates vascular endothelium and increases vascular permeability?

A

-TNF-Alpha

25
Q

What pro-inflammatory cytokine activates lymphocytes and increases antibody production?

A

-IL-6

26
Q

What pro-inflammatory cytokines is a chemotactic factor that recruits neutrophils, basophils, and T cells to site of infection?

A

-CXCL8

27
Q

What pro-inflammatory cytokine activates NK cells and induces the differentiation of CD4 T cells into Th1 cells?

A

-IL-12

28
Q

What do inflammatory cytokines stimulate?

A

-The liver to produce acute phase response

29
Q

When IL-6 concentrations are increased what acute phase proteins are increased?

A
  • C-reactive protein
  • Mannose-binding lectins
  • LPS binding protein
  • Complement components
  • Fibrinogen (coagulation factors)
30
Q

What types of immune cells swarm to damaged or infected tissue?

A
  • Neutrophils

- Monocytes

31
Q

When does the interferon response occur?

A

-When infection establishes

32
Q

T/F The Interferon response induces resistance to viral replication in all cells

A

True

33
Q

T/F Gamma:Delta T cells are also APCs

A

True

34
Q

What two cell types release perforins and granzymes?

A
  • CD8

- NK cells

35
Q

How long does it take for antigens to enter the lymph nodes?

A

-Minutes

36
Q

How many days does it take for the Egression of effector cells from a lymph node to occur?

A

-3-4 days

37
Q

What two cells form the cognate pair at the follicle boundary?

A

-B and T cells

38
Q

When TFH cells aid in B cell activation and it stimulates B cell proliferation what occurs?

A

-It induces centroblasts formation

39
Q

The primary focus for expansion of antigen-activated B cells is in what area?

A

-Medullary cords

40
Q

The secondary focus for expansion of antigen-activated B cells is where?

A

-Primary follicle

41
Q

What are the four effector function of antibodies secreted from plasma cells?

A
  • Virus and toxin neutralization
  • Opsonization
  • Complement fixation
  • Antibody-Dependent Cell-mediated cytotoxicity
42
Q

As the adaptive immune system improves over time what is the major antibody that is released?

A

-IgG

43
Q

The inhibition of peripheral Th17 cells induce what?

A

-T reg cell development

44
Q

When IFN-gamma is released from Th1 cells what does it do?

A

-Inhibit TH2 proliferation

45
Q

An activated Th2 cell secretes TGF Beta and IL-10, what do these Cytokines inhibit?

A

-Activation and growth of Th1 cells

Host and Defense 2020 (61 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions