4/10/17 Malaria GRANGER TEST #3 Flashcards
What three malaria causing organisms can be managed as outpatients and are benign?
- Pl. vivax
- Pl. ovale
- Pl. malariae
What malaria causing organism is malignant (very bad)?
-Pl. falciparum
What is a nasal flare and intercostal retraction characteristic of?
-Metabloic acidosis
Who is most at risk for death due to malaria?
- Children 6 months to 6 years
- Non-immune adults
- Pregnancy
- Emigrants returning from home visits
What are three conditions that are associated with malaria?
- Respiratory distress
- Sever anemia
- Impaired consciousness
What condition that is associated with malaria has the highest mortality rate?
-People with all three
if individual then respiratory distress
Who does malaria rarely occur in?
- Sickle cell trait in children
- Denizens of endemic areas (immune adults)
What strain of malaria has no latent stage in the liver?
-Pl. falciparum
The destruction of what cells lead to sever malaria?
-Red blood cells
What cycle causes the replication of malaria cells, Sporogony or shizogany?
-Shizogany
Where do the mature forms of malaria found?
-Adherent to micro vessels in the brain
T/F The benefits to the parasite of sequestration is the ability to evade splenic clearance
True
What does having the post capillary venule blood pH low at 7.1 do for the parasite of malaria?
-Favors parasite replication
When malaria is sequestered the post-capillary venule pCO2 is high, what does that do for the parasite?
-Favors parasite replication
T/F Pl. falciparum infects RBCs of any age
True
What are three pronged approaches for combating malaria in the world?
- Insecticide impregnated bed nets
- Residual insecticide spraying
- Pre-emptive treatment with ACT
When comparing malaria vs septic shock which one has sever anemia associated with it?
-Malaria
When comparing malaria vs septic shock which one advances rapidly?
-Both
When comparing malaria vs septic shock which one has lactic acidosis associated with it?
-Septic shock
When comparing malaria vs septic shock which one has complex acidosis?
-Malaria
When comparing malaria vs septic shock which one is driven by cytokine storm?
-Septic shock
When comparing malaria vs septic shock which one is driven by sequestration?
-Malaria
When comparing malaria vs septic shock which one has blood pressure preserved?
-Malaria
When comparing malaria vs septic shock which one is associated with having a coma?
-Malaria
What are four ways to help prevent getting malaria?
- Malaria prophylaxis with anti-malarials weekly
- Mosquito repellant with DEET
- Permethrin-impregnated bed nets
- Permethrin treated clothing
