2/7/17 Dr. Florell Cutaneous Infection TEST #2 Flashcards

1
Q

What does the stratum corneum prevent?

A

-Water loss and chemical entry

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2
Q

The dermis is tough and repels what?

A

-physical insults

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3
Q

What two layers are found in the dermis?

A
  • Papillary dermis

- Reticular dermis

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4
Q

What is the Adnexa?

A
  • Hair follicles

- Sweat glands

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5
Q

What are two types of bacterial cutaneous infections?

A
  • Impetigo

- Follliculitis

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6
Q

What are three types of viral cutaneous infections?

A
  • Herpes virus
  • Molluscum contagiosum
  • Verruca vulgaris
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7
Q

What type of cocci is on the normal skin flora?

A

-Aerobic cocci

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8
Q

What percent of outpaitient dermal visits are bacterial?

A

-20%

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9
Q

If you have impetigo what part of the skin does it affect?

A

-Epidermis

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10
Q

If you have Folliculitis what part of the skin unit does it affect?

A

-Appendages

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11
Q

What are three types of fungal cutaneous infections?

A
  • Tinea versicolor
  • Tinea corporis
  • Deep fungal infection
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12
Q

What are two types of infestation cutaneous infections?

A
  • Scabies

- Myiasis

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13
Q

What are most cutaneous infections caused by?

A

-Staph aureus

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14
Q

What are three bacteria causes of Impetigo?

A
  • Staphylococcal
  • Streptococcal
  • Mixed infections
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15
Q

What is the main bacterial cause of Impetigo?

A

-Staphylococcal

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16
Q

How does impetigo manifest itself?

A

-Thin, straw colored discharge noted which dries to form golden’yellow crusts

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17
Q

What is impetigo most commonly found on people?

A
  • Exposed areas
  • Face
  • Hands
  • Neck
  • extremities
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18
Q

What are the treatments for impetigo?

A
  • Antibiotic ointment

- Systemic antibiotic

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19
Q

If a patient comes into your clinic with discrete, thin-walled vesicles that become pustular and rupture what might they have?

A

-Impetigo

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20
Q

If you see a hair coming straight from the center of a pustule what might that be indicative of?

A

-Some type of folliculitis

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21
Q

In folliculitis what are the shape of the pustules?

A

-Dome-shaped around hair follicles

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22
Q

In bacterial folliculitis what is the most common cause?

A

-Staph aureus

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23
Q

What are the treatments for folliculitis?

A
  • Decrease bacterial load (antibacterial soap)

- Topical or systemic antibiotics

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24
Q

What type of parasite are viruses?

A

-Obligatory intracellular

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25
What three viral infections involve the epidermis?
- Molluscum cotagiosum - Herpesvirus - Verruca
26
What type of viral infection involves the skin appendages (hair follicle)?
-Folliculitis (herpesvirus)
27
What does a positive interpretation require from a Tzanck smear for herpesvirus?
- Multi-nucleated keratinocytes | - Peripheral marginization of chromatin
28
After primary infection with Herpes (varicella) Zoster where does it remain latent at?
-Dorsal root ganglion cells
29
What is the treatment of Herpes (varicella) Zoster?
-Antiviral therapy
30
What type of Virus is herpesvirus infection?
-Double Stranded DNA
31
What type of virus is varicella virus?
-Double stranded DNA
32
What type of virus is cytomegalovirus?
-double stranded DNA
33
What type of virus is Epstein-Barr virus?
-Double stranded DNA
34
Where do you typically see oral herpes?
- Keratinized/masticatory mucosa - palate - gingiva - tongue
35
What type of herpesvirus is a life threatening infection of a pre-existing skin rash, usually atopic dermatitis?
-Eczema herpeticum
36
What is oral hairy leukoplakia associated with?
-Epstein-Barr virus infection
37
Who does oral hairy leukoplakia occur most commonly in?
-HIV infected patients
38
What are three other groups of people besides HIV patients can you find oral hairy leukoplakia?
- Chemotherapy - Organ transplant - Leukemia
39
What is the treatment for oral hairy leukoplakia?
- Systemic antiviral therapy such as: - Acyclovir - Valacyclovir - Famiciclovir
40
What is Molluscum contagiosum caused by?
-Poxvirus
41
What are three groups that you generally find molluscum contagiosum in?
- Young children - Sexually active adults - Systemic T-cell immunosupression (HIV)
42
How is Molluscum contagiosum transmitted?
-Direct skin to skin contact (especially if skin is wet)
43
If you see Hnderson-Paterson bodies in a histology side what does that indicate?
-Molluscum contagiosum
44
What is the treatment for molluscum?
-Spontaneous resolution within 2 yrs
45
If you see a thick granular cell layer with koilocytes what does that indicate?
-Verrucous epidermal
46
What are two types of fungal infections that effect the epidermis?
- Tinea versicolor | - Dermatophytosis
47
If a rash is scaly what type of preparation should you do?
-KOH preparation
48
If you have hyphae and yeast in the epidermis what is that indicative of?
-Tinea versicolor
49
What causes Tinea versicolor?
-Pityrosporum orbiculare
50
Where is the most common site of infection on a person with Tinea versicolor?
-Upper trunk
51
What are the treatments for Tinea versicolor?
-Topical or systemic antifungal agent
52
Where can Dermatophytes survive on?
-Only on dead keratin skin, hair and nails
53
T/F Dermatophytes can survive in the mouth or vagina where the stratum corneum does not form.
False | They can NOT
54
If you have hyphae present in largest numbers at the advancing annular edge what is that indicative of?
-Dermatophytes
55
What is the treatment of dermatophytes?
-Oral or topical antifungal
56
What is the mariners wheel found in a histo slide indicitive of?
-Paracoccidiodomycosis
57
What are most fungal infections a manifestation of?
-Systemic infections
58
T/F Primary infections of deep fungal pathogens are introduced directly into the skin via puncture, abrasion, trauma resulting in an ulcer or verrucous lesion
True
59
Who are most opportunistic fungal diseases seen in?
-Patients with leukemia or hematologic neoplasia
60
What are the two types of opportunistic deep fungal infections?
- Candidiasis | - Aspergillosis
61
T/F With scabies you will have intense itching
True
62
If you have pruritic papular lesion, excorations and burrows what might they have?
-Scabies
63
What is Myiasis?
-Infestation of human tissue by fly larvae
64
If you have a dermatophyte infection (annular scaling plaque) what should the next step be?
-KOH prep