4/27/16 HIV WINKLER TEST FINAL Flashcards
What type of HIV may be less virulent and have a longer latency period?
-HIV-2
What type of test can detect either one or both types of HIV?
-EIA
Worldwide what is the prominant type of HIV?
-HIV-1
What are the main cells infected by HIV?
- CD4 T cells (main one)
- Monocytes
- Macrophages
If you give a mother what HIV treating drug will it almost completely eliminate the chance of the baby getting HIV from mom?
-AZT
What are the six steps in HIV life cycle?
- Binding
- Fusion
- Reverse transcription
- Integration
- Assembly
- Budding
In the current HAART (cART) therapy how many drugs are combined?
-3 or more drugs
In the cART therapy combination how many nucleoside analogue RT inhibitors are used?
-Usually two
T/F HIV can now be considered a chronic infection
True
Do successfully treated HIV patients live as long as an uninfected individuals?
-No it is shorter than normal but longer than not being treated at all
With HIV drugs have a hepatotoxicity side effect?
- NNRTI
- PI
What are four dental concerns that deal with the hepatotoxicity effects of HIV drugs?
- Local anesthetics
- antibiotics
- Pain Killers
- Antifungals (because these are metabolized in the liver)
What HIV drug is Hyper lipidemia associated with?
-PI (Protease Inhibitors)
Osteonecrosis is associated with what HIV drug?
-PIs
T/F Immunocrompromised individuals have a greater risk for post operative complications
True
T/F HAART therapy has reduced the amount of oral lesions caused by HIV
True
With HAART therapy has there been a change in the incidence of candidiasis?
-No
With HAARt therapy what has happened with salivary gland disease and oral warts?
-Increases in both
What are oral manifestations of HIV indicative of?
-Disease progression
What CD4 count levels should you be worried about in HIV pts?
-Less than 200
T/F Hairy leukoplakia is not associated with HIV
False
-It is
T/F Oral candidiasis has declined in HIV patients since HAART therapy
True
Has Kapsoi’s sarcoma increased or decreased in HIV pts on HAART therapy
Decreased
Has pappilomas increased or decreased in HIV pts on HAART therapy?
-Increased