4/14/17 Immune memory and vaccination GERMAN FINAL TEST Flashcards
What do antibodies developed during the primary response provide?
-Protective immunity
What are the three types of adaptive memory cells?
- Memory B cells
- Memory plasma cells
- Memory T cells
Where do most of the memory plasma cells reside?
-Bone marrow
Where do most of the memory T cells reside?
-Secondary lymphoid tissues
Besides the bone marrow and secondary lymphoid tissues what are two other areas that you will find memory cells?
- Peripheral tissue
- Circulation
Do primary effector cells or memory cells have a broad antigen response?
-Primary effector cells
Do primary effector or memory cells have a specific restricted antigen response?
-Memory cells
Do primary effector or memory cells have easy activation?
-Memory cels
Do primary effector or memory cells have to go through multiple activation steps and signals?
-Primary effector cells
Do primary effector or memory cells have clonal selection and expansion?
-Primary effector
Do primary effector or memory cells have just clonal expansion because they have already been selected?
-Memory cells
Do primary effector or memory cells have B cell target refinement that is unnecessary?
-Memory cells
Do primary effector or memory cells have B cells that must undergo target refinement?
-Primary effector
What are the refinements that B cells must do while a primary effector cell?
- Somatic hypermutation
- Class switching
Do primary effector or memory cells die after several days?
-Primary effector
When a primary cell has undergone somatic hypermutation can it go through it again?
-No
Do primary effector cells or memory cells persists for months and replicate providing long term immunity?
-Memory cells
