9.6 Pulmonary Hypertension Flashcards
1
Q
What is the normal pressure in the pulmonary circuit?
A
10 mmHg
2
Q
What are some of the characteristics of pulmonary HTN?
A
- Plexiform lesions
- Atherosclerosis of pulmonary artery
- Smooth muscle hypertrophy
3
Q
What does pulmonary HTN lead to?
A
- RVH
- Cor pulmonale
4
Q
What are the main presentations of pulmonary hypertension?
A
- Exertional dyspnea
- RV heart failure
5
Q
What is the classical patient of pulmonary HTN?
A
Young adult females
6
Q
What is the cause of familial pulmonary HTN?
A
Inactivation mutations in BMPR2 which causes proliferation of vascular smooth muscle
7
Q
What is the cause of secondary pulmonary HTN?
A
- Hypoxemia of the lung
- Pulmonary embolism
- Increased volume in the pulmonary circuit