14.4 Prostate

Question 1

Acute Prostatitis

Answer 1

Acute inflammation of the prostate often due to bacteria

Question 2

What are the common pathogens in acute prostatitis in young males?

Answer 2

C. trichromatic and N. gonorrhea

Question 3

What are the common pathogens in acute prostatitis in older males?

Answer 3

E. coli and Pseudomonas

Question 4

What is the presentation of acute prostatitis?

Answer 4

Dysuria with fever and chills - prostate will be tender and boggy

Question 5

Chronic Prostatitis

Answer 5

Presents as dysuria with pelvic or low back pain

Question 6

Benign Prostatic Hyperplasia

Answer 6

Hyperplasia of prostatic stroma and glands that is related to age and can cause urethral obstruction

Question 7

What hormone is BPH associated with?

Answer 7

DHT

Question 8

Is there increased risk for cancer with BPH?

Answer 8

No

Question 9

What will happen to the bladder with BPH?

Answer 9

Hypertrophy

Question 10

What marker will be elevated in BPH?

Answer 10

PSA (slight)

Question 11

What are the treatments for BPH?

Answer 11

• alpha1-antagonist
• selective alpha1A-antagonist
• 5alpha-reductase inhibitor

Question 12

Prostate Adenocarcinoma

Answer 12

Malignant proliferation of prostate glands

Question 13

What is the most common location for prostate cancer?

Answer 13

Posterior Periphery

Question 14

What are the screening methods for prostate cancer?

Answer 14

• Digital Rectal Exam

- PSA Levels

Question 15

What is a decrease in the percentage of free-PSA suggestive of?

Answer 15

Cancer

Question 16

What is the Gleason grading system based on?

Answer 16

Based on cellular architecture and not nuclear atypia

Question 17

Where does prostate cancer tend to spread to?

Answer 17

Lumbar spine with osteoblastic metastases

Question 18

What is treatment for prostate cancer?

Answer 18

• Prostatectomy
• GnRH analogs - leuprolide
• Androgen receptor inhibitor - flutamide