11.2 Gallbladder and Biliary Tract Flashcards
Biliary Atresia
Failure to form or the destruction of the extra hepatic biliary tree that leads to biliary obstruction
What are the clinical presentations of biliary atresia?
- Jaundice (conjugated bilirubin)
- Cirrhosis
Cholelithiasis
Gall stones that are due to the precipitation of cholesterol or bilirubin in the bile
What is the most common type of gall stone?
Cholesterol Stone
Are cholesterol stones radio-opaque or transluscent
Translucent
What are the risk factors of cholesterol stones?
- Age
- Estrogen
- Crohn Disease (damage to terminal ileum)
- Cirrhosis
- Native American Ethnicity
Do bilirubin stones show up on x-ray?
Yes
What are the risk factors of bilirubin stones?
- Hemolysis
- Biliary Tract Infection
Biliary Colic
Waxing and waning RUQ pain due to the contraction of the gall bladder against stone lodged in the cystic duct
Acute Cholecystitis
Acute inflammation of the gallbladder due to impacted stone in the cystic duct that cause dilatation with ischemia and inflammation
How does acute cholecystitis present?
- RUQ pain that radiates to the right shoulder or scapula
- Fever with increased WBCs
What will the labs show for acute cholecystitis?
Increased serum alkaline phosphatase
Chronic Cholecystitis
Chronic inflammation of the gall bladder due to chemical irritation from longtime cholelithiasis
What is a hallmark of chronic cholelithiasis?
Rokitansky-Aschoff Sinuses
What is a late complication of chronic cholelithiasis?
Porcelain Gallbladder
Ascending Cholangitis
Bacterial infection of the bile ducts that is due to an ascending infection
What can increase the incidence of ascending cholangitis?
Choledolithiasis - stone within the duct
Gallstone Ileus
Stone enters and obstructs the small bowel and is due to cholecystitis with fistula between the gallbladder and the small bowel
Gallbladder Carcinoma
Adenomcarcinoma from glandular epithelium that presents with cholecystitis
What is a major risk factor for gallbladder carcinoma?
Gallstones and porcelain gallbladder