18.5 Neuromuscular Junction Flashcards
1
Q
Myasthenia Gravis
A
Antibodies that prevent ACh binding as they compete with ACh
2
Q
What gender is more affected by myasthenia gravis?
A
Women
3
Q
What is myasthenia gravis associated with?
A
Thyme hyperplasia or thymoma
4
Q
Lambert-Eaton Syndrome
A
Antibodies against the presynaptic calcium channels at the NMJ leading to impaired ACh release
5
Q
What is the most common etiology of Lambert-Eaton syndrome?
A
Paraneoplastic syndrome most commonly due to small cell carcinoma