18.4 Skeletal Muscle

Question 1

Dermatomyositis

Answer 1

Inflammatory disorder of the skin AND skeletal muscle with unknown etiology

Question 2

What can dermatomyositis be associated with?

Answer 2

Carcinoma

Question 3

What is the presentation of dermatomyositis?

Answer 3

Proximal muscle weakness

Question 4

Besides lupus what can a molar rash be indicative of?

Answer 4

Dermatomyositis

Question 5

What area is inflamed in dermatomyositis?

Answer 5

Perimysial inflammation

Question 6

Polymyositis

Answer 6

Inflammatory disorder of skeletal muscle without skin involvement

Question 7

What are is inflamed in polymyositis?

Answer 7

Endomysial inflammation

Question 8

X-linked Muscular Dystrophy

Answer 8

Degenerative disorder of muscle wasting with replacement of skeletal muscle by adipose tissue

Question 9

What is the cause of x-linked muscular dystrophy?

Answer 9

Due to deletions of dystrophin - disease AKA Duchenne’s Muscular Dystrophy

Question 10

What disease can calf pseudo hypertrophy indicate?

Answer 10

X-linked Muscular Dystrophy

Question 11

Becker Muscular Dystrophy

Answer 11

Similar to Duchenne’s but is milder as it is a dystrophin mutation rather than a deletion