3.4 Clinical Characteristics Flashcards
What are some features of benign tumors?
- Slow growth
- Well circumscribed
- Mobile
- Distinct
What are some features of malignant tumors?
- Rapid growth
- Not distinct
- Disorganized
- Invasive
What is the absolute distinguishing feature between benign and malignant tumors?
Metastasis. Benign tumors NEVER metastasize.
What intermediate filament makes up epithelium?
Keratin
What intermediate filament makes up mesenchyme?
Vimentin
What intermediate filament makes up muscle cells?
Desmin
What intermediate filament makes up neuroglia?
GFAP
What intermediate filament makes up neurons?
Neurofilament
What marker is commonly used for prostate cancer?
PSA
What marker is commonly used for neuroendocrine cells?
Chromogranin
What is a good marker for melanoma?
S100
What is required for diagnosis of cancer?
Tissue biopsy
What is staging of cancer based on?
Size and spread
What is the most important prognostic factor in cancer?
Metastasis