3.3 Tumor Progression Flashcards
1
Q
What is the hallmark of a malignant tumor?
A
Invasion and spread
2
Q
Why do tumor cells down regulate E cadherin?
A
This allows the cells to detach themselves from the basement membrane, leading to metastasis
3
Q
What kind of spread is characteristic of sarcomas?
A
Hematogenous spread
4
Q
What kind of spread is characteristic of carcinomas?
A
Lymphatic spread
5
Q
What are the exceptions - the carcinomas that spread in the blood?
A
Renal Cell Carcinoma
6
Q
What is omental “caking?”
A
It occurs with ovarian cancer where it seeds the body cavity and takes over the omentum, turning it into a cake like consistency
