Renal Day 2 Flashcards
what are macula densa cells?
cells that detect content of tubular fluid to know what to pass through (on distal convoluted tubule that sits next to afferent arteriole)
what are mesangial cells?
border glomerulus and function as precapillary sphinters to control pressure through glomerulus
what is the tubular pole?
where proxima convoluted tubule emerges off bowman’s capusel
what are podocytes?
filtration slits that sit outside the fenestrated glomerulus
what type of cells makes up the tubules of a nephron?
simple cuboidal with microvilli
what type of cells make up the loop of Henle?
simple squamous
what is normal plasma osmolarity?
300
where does most of reabsorption occur?
proximal convoluted tubule
what happens to tubular fluid osmolality as it passes through the loop of Henle?
- descending osmolality increases
- ascending osmolality decreases and becomes hypoosmotic
- collecting duct urine is dilute and has low osmolality
what is the normal urine output per day?
1-2L
which leg of the loop of Henle is immpermeable to water?
ascending limb
which leg of the loop of Henle is not permeable to solutes?
descending loop
where are principle cells located?
distal convoluted tubule and collecting duct
-use aldosterone and ADH to reabsorb more water
what are intercalated cells?
they control and monitor pH by secretion of hydrogen and potassium into the tubular fluid
located at distal end of DCT
where are the two places that contain transitional epithelum?
ureters
bladder
