Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Medicine > Innate Immunity > Flashcards

Innate Immunity Flashcards

1
Q

which areas of the body do not have lymphatic vessels?

A

CNS
spleen
bone marrow
avascular structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

which cells are most abundant in the lymph nodes?

A

lymphocytes

macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is lymph fluid called?

A

chyle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which two mechanisms facilitate movement of chyle?

A

contraction of skeletal muscle

respiratory pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are Hassel’s corpuscles/

A

located in the medulla of the thymus

epithelial cells filled with keratohyaline granules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is the role of nurse cells?

A

secrete thymic hormones that mature and differentiate T-cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is located in the outer cortex of lymph nodes?

A

B cells
macrophages
dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is located in the medulla of lymph nodes?

A

B cells and macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is located in the inner cortex of lymph nodes?

A

T cells

dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what CT fibers support lymph nodes?

A

reticular fiber

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is found in the white pulp of the spleen?

A

B and T cells surrounding branches of the splenic artery

Immune system component

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is found in the red pulp of the spleen?

A

blood-filled venous sinuses
sinusoid capillaries
removes worn out RBC and WBC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

which chemical on the skin is resistant to bacterial enzymes?

A

keratin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

which features do mucosal membranes use to fight bacteria?

A 
acidity
sebum contains chemical toxin
stomach digests proteins
tenacious to trap organisms
cilia to move them out
normal flora
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

which cells produce interferon?

A

virally-infected lymphocytes and macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what does interferon do?

A

induces synthesis of antiviral proteins

17
Q

which cells produce alpha interferon?

A

leukocytes

18
Q

which cells produce beta interferon?

A

fibroblasts

19
Q

which cells produce gamma interferon?

A

lymphocytes

20
Q

what 3 things does the complement system do?

A
  1. promotes phagocytosis
  2. causes inflammation
  3. causes cytolysis
21
Q

how does iron binding contribute to innate immunity?

A

traps iron, which bacteria needs to replicate

22
Q

what do AMP’s do?

A

work in a variety of ways against many organisms

23
Q

which cell has the selectin?

A

blood vessel endothelial cell

24
Q

which cell has the integrin?

A

neutrophil

25
Q

what two components does opsonization need?

A
  1. complement (innate)

2. IgG (adaptive)

26
Q

what do defensins do?

A

pierce a whole in the bacterium cell wall

27
Q

which cells can kill cancer and virally infected cells?

A

NK cells

28
Q

what important areas contain NK cells?

A

spleen
bone marrow
lymph nodes

29
Q

how do NK cells know which cells to kill?

A

contains a stress-induced glycoprotein on cell surface

lacks MHC 1 protein

30
Q

what two proteins do NK cells use to kill cells?

A

perforins

granzymes

31
Q

what do granzymes do?

A

penetrate bacterial cells and destroy their insides

32
Q

what are 2 main functions of the inflammatory response?

A
  1. vasodilation

2. increased capillary permeability

33
Q

which 3 things cause pain from injury?

A
  1. edema
  2. prostaglandins
  3. bradykinin
34
Q

which coagulation factor is responsible for the kinin cascade?

A

factor 12

35
Q

which prostaglandin is responsible for platelet aggregation?

A

thrombaxane

36
Q

which prostaglandin is responsible for protecting tissue surrounding the clot?

A

PGI2

37
Q

what are the 3 results of the complement system?

A
  1. opsonization
  2. MAC attack
  3. causes inflammation
38
Q

what stimulates zinc and iron binding?

A

mild-moderate fever

39
Q

what is the role of TLR?

A

mediate innate immunity when activated

Medicine (146 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions