Movement disorders Flashcards
what is the most common action or postural tremor?
essential tremor
what is the pattern of inheritance of ET?
AD
what is the DOC for essential tremor?
primidone
what type of ET might indicate a use for botox?
voice tremor
what is Myerson’s tap?
tapping bridge of nose produces sustained blink response
what is Shy-Drager?
Parkinson PLUS autonomic insufficiency (anhydrosis, impotence, etc)
What is PSP?
progressive, supranuclear palsy
Parkinsons PLUS gaze paralysis (falls down the stairs)-usu. no tremor
what is often the first sign of HD?
personality changes
what is idiopathic torsion dystonia?
childhood onset usu. in legs (FH, more severe)
adult onset usu. in arms/axial (not as severe)
what is akathesia?
dystonia
what is coprolalia?
tourrettes outbursts of obscene speech
what is echolalia?
repeating what other’s say “parroting”
what is palilalia?
repeating words or phrases (OCD)
when would you use oxitriptan?
f/ an anoxic brain injury
which test in MG has a correlation to progression of dz?
interleukin 2
which routine test in MG has NO correlation to progression of dz?
anti-ach receptor antibodies
how do you treat MG?
ChEI
prednisone/(cyclosporie/Imuran) if refractory to steroids
acute therapy = plasmapheresis
what would be present in CSF of an MS pt experiencing an exacerbation?
oligoclonal bands
how do you treat MS exacerbations?
steroids
plasmapheresis
how do you prophylax MS?
B-interferon
glatiramer acetate
humanized monoclonal antibodies
anti-CA
which drugs should be avoided in parkinsons/
phenergan
metoclopramide
antiemetics
how do you treat tourrettes?
haldol 0.5 mg
prolixin, orap
botox
what do you use to treat alzheimers?
donepezil (aricept) 5-10mg
galantamine (razadyne) 8-12 mg BID maint
rivastigmine (exelon) 3-6 mg BID maint
Memantine (Namenda) 10 mg BID maint
which AD drug has to be dose adjusted for CrCl of less that 60?
namenda
10 mg QD
contraindicated for CrCl <30
which AD drug should avoid use with mucinex DM, and ketamine?
namenda
