Wed Wk 6 Mixed 3 Flashcards
SCHIZOID prefers to be __/__/__
schizotypal has odd __/__
no delusions/hallucinations like __
also have social __
Familial __ is deficiency of LPL/ApoC2
elevated __ w acute panc/lipema retinalis and eruptive xanthomas
Familial __ has defect in LDL receptor/ApoB100
elevated LDL w premature __ and xanthelasma
Familial dysbetalipoproteinemia due to defect in __
cannot bind hepatic __ thus cannot remove constituents
/ accumulate
see Premature CAD and __
Familial __ has inc VLDL
assc w C/P/O
ApoA1/LCAT def leads to high _ and low HDL as esterification is not possible
alone, detached, nonemotional
perceptions/beliefs
schizophrenia
anxiety
chylomicronemia chylomicrons Hypercholesterolemia CAD apoE receptors chylomicrons/VLDL xanthomas hyperTG CAD, pancreatitis, obesity
cholesterol
metyrapone stimulation test blocks _ synthesis by inhibiting 11Bhydroxylase in ZF
__ accumulates and is converted to 17OH corticosteroids
these levels should __ w intact HPA axis
Lunate is more __ articulation w radius
__ is found above scaphoid
_ is found below the hamate
pt w significant renal dysfxn has accumulation of __ toxins
this is a __ platelet disorder that impairs aggregation
bleeding time is __ but all other coagulopathy studies are __
TCR gene rearrangement of T cells rearranges __ chain genes
this leads to both / being expressed
then __ chain is rearranged w positive/negative selection
mature T cells then lose _ of antigens
macrophages cannot present to __ t cells
cortisol
11deoxycortisol
rise
medial
trapezium
triquetrum
UREMIC
QUALITATIVE
HIGH
NORMAL
Beta
CD4/CD8
alpha
1
naive
in MG, there is a dec nmber of fxnal __ receptors
thus, THRESHOLD POTENTIAL is NOT __ as less cation channels can open
this reduces __ of muscle contraction
muscle cells then do not __
tx w __ a cholinesterase inhib
use selective muscarinic antags G, H, P to reduce SE in GI tract
do not affect __ which uses nicotinic receptors
M/T are other drugs that can cause DILE
no / comps, no malar rash
Acetylcholine
REACHED
amplitude
depolarize
pyridostigmine
glycopyrrolate, hyoscyamine, propantheline
skeletal muscle
minocycline, TNF a inhibitors
CNS/renal
astrocytes regulate NT by taking up __ to prevent excess excitation
converted w ammonia to __ which released and taken up by neurons
converted back to __ for use as NT
w inc ammonia, __ prodxn is high
this inc astrocyte swelling and impairs __ releas
hyperammonemia then depletes amount of __ available for conversion to glutamate, thus dec __ NT
precipitation of Hepatic enceph Drugs like N/S hypovolemia D electrolyte \_\_ inc nitrogen from \_\_ infections and shunts sx include A/A/A tx by dec \_\_
glutamate glutamine glutamate glutamine glutamine glutamine, excitatory
narcotics, sedatives diarrhea deficiencies gi bleed AMS, ataxia, asterixis ammonia levels
__ is tumor of PNS from schwann cells
biphasic high cell areas are __ pattern
intermixed w myxoid low cellularity areas __ pattern
spindle cells form palisading patterns around nuclear free zone aka __ body
always stains __ positive
can occur at any CN except __ as it is covered in oligodendrocytes
most common location is _
__ tumor has bizarre glial cells w mitotic figures, pseudopalisading necrosis, neovasc and hemorrhage
found in __ matter
brain mets form along _ jxn
central necrosis w surrounding __
masses are __ circumscribed
schwannoma antoni a antoni b verocay S100 CN2 cerebellopontine angle
glioblastoma
white
G/W
glial scar
well
use __ to model linear relationship w dependent variable and independent variable
HCV varies at __ genomic regions
no __ proofreading activity
Courvoisier sign indicates adenocarcinoma at __ of pancreas
can obstruct __ w obstructive jaundice/pale stools
RF include A/S/D/C
Identify __ syndrome as cells cultured in folate deficient medium will have no growth on X chromo
B globin genes on chromo _
linear regression
hypervariable
3’-5’
HEAD
bile ducts
age, smoking, diabetes, chronic pancreatitis
Fragile X syndrome
11
acute hep b may lead to __ like syndrome w joint pain and urticaria
can use rapid __ to quickly diagnose active H pylori infection
due to __ which converts gastric urea to ammonia w alkalinization of test
__ is reagent that is used
for purified RNA to induce viral protein synthesis in cell, it must act as __
must be __ to have enzymes extracted
trypsin can activate __ or other zymogens
thus, __ is secreted by panc acinar cells to be inhibitor
trypsin also cleaves __ to make it inactive
hereditary pancreatitis due to mutation in Trypsinogen or __ gene
trypsin is not __ to inactivation
L/A are panc enzymes that are not zymogens
serum sickness like
urease
urease
Phenol red
mRNA
naked
itself
SPINK1
itself
SPINK1
susceptible
lipase, amylase
Iron is absorbed in /
thus, must be replaced in _
w antrum removed, less __ released and diminishes iron absorption
lack of __ in pregnancy impairs fetal kidney development
can also impair cranial __ and lead to hypocalvaria
use / for HTN in pregnancy instead
avoid __ in pregnancy as it might close the DA
dec lung __ promotes compression of airways in pt w COPD
w exercise, inc air trapped in lungs reduces TV, and pt has __ hyperinflation causing SOB
alcohol binds and enhances _ activity over time, dec GABA \_\_ leads to tolerance alcohol withdrawal occurs w/in \_\_ see I/T/A/A seizures begin w/in \_\_ hrs delirium tremens/agitation occur \_\_ use \_\_ benzos for withdrawal as it self tapers use \_\_ in pt w liver dz
duodenum, proximal jejunum
gastric acid
AT2
vascularization
Amethyldopa, Labetalol
NSAIDs
elasticity
dynamic
GABA sensitivity 12hrs insomnia, tremulousness, anxiety, autonomic hyperreactivity 48 next
long acting
lorazepam, oxazepam, temazepam
CCl4 is converted to CCl3 via __ system
Free rads form/release __ and cause lipid peroxidation
eventually, this leads to inc __ of cell membranes
tumor cells detach from surrounding cells by DOWNREGULATING __
then adhere to BM via __
invade via secretion of proteolytic enzymes like __
this distinguishes __ tumor from CIS
Essential/fmailial tremor inherited __
worsens when maintaining _
sx improve w __
tx w __
Osteonecrosis due to \_\_ occlusion like SCD/decomp \_\_ or alcohol abuse traumatic fracture or V\_\_ see pain on \_\_ and dec range of motion \_\_ shaped zone of necrosis articular cartilage may be _/_ dead bony trabeculae w empty \_\_ see \_\_ of adipocytes all due to impaired \_\_ to bone, usually femoral head
p450
H2O2
PERMEABILITY
E cadherins
LAMININS
MMP
invasive
AD
posture
alcohol intake
propanolol
thrombotic GC vasculitis weight bearing wedge distorted/detached lacunae necrosis blood supply
long glands w villi like projections is __ adenoma
often __ and sessile w cauliflower like proection
__ adenomas have dysplastic mucosal cells w tube shaped glands
__ is most likely to undergo malignant transformation
can also secrete __ w secretory diarrhea, hypovolemia and electrolyte probs
__ polyps have mucosal glands, smooth muscle, CT
seen in /
_ polpys are well differentiated and are asx
all heart chambers except __ lie medial to MCL
lung mediastinal surface has __ to accomodate heart
in exercise, SNS discharge inc contraction of __
this rises __ to drive blood to skeletal muscle
this leads to dec __ as arteriolar vasodilation facilitates blood flow to skeletal muscle
VILLOUS LARGE tubular VILLOUS ADENOMA watery mucus
hamartomous
PJS, juvenile polyposis
hyperplastic
LV
cardiac impression
arterioles
SBP
dec SVR
Babesiosis due to __
Ixodes tick vector in __ US
flu like sx, can lead to much more __ manifestations w asplenia
see hemolytic anemia, T and inc __
wright giemsa stain shows _ such as maltese cross/rings
granulocyes w morula in cytoplasm has __ due to Ixodes tick
hepatic centrilobular necrosis causes death of hepatocytes around terminal __
periportal hepatic fibrosis indicates __
w ischemia, cardiac myocytes must use __ glycolysis
cannot keep up, thus / accumulates inside cells
these inc conc attract __ w cell swelling
Babesia microti NE severe thrombocytopenia, LFTs intraerythrocytic parasites anaplasmosis
portal vein
chronic hepatitis
anaerobic
Na/Ca
water
__ is malabsorptive cx in pt w SB resection/CD
loss of __ leads to dec intestinal transit time
thus, postprandial voluminous __ w WL and malabsorption ensues
_ syndrome occurs after gastric bypass surgery/damage to pyloric sphincter
hyperosmolar __ enters SI and causes rapid shift of fluids
results in GI sx and /
HHV6 is one of MCC of __ seizure
rash after 3-5 days of high fever starts on __ and spreads to face
Forcheimer spots on soft palate indicate __
short bowel syndrome
absorptive surface
diarrhea
dumping
chyme
diaphoresis, flushing
febrile
trunk
RUBELLA
