Friday Wk 4 Mixed 1 Flashcards
SCC contains F__ polyhedral/ovoid cells w eosinophilic cytoplasm
bubble tst is used to identify a __ shunt
usually assc w patent __ or __
in development, FO shunts oxygenated blood from __ to __ heart
w dec PVR and inc LA pressure, septum primum shuts against __
this closes F__, but incomplete fusion is most common defect
concern for paradoxical embolism w inc __ pressure
ASD results from __ of septum primum/secundum
45s rRNA is always located in nucleus, and is cleaved into sections via RNA poly __
RNA poly 1 also assembles Ribosomal __ together
protein is translated in _ and goes to nucleolus for assembly
then enters cytoplasm to begin __
flattened
RtL FO ASD right, left Secundum
FO
RA
aplasia
1
subunits
cytoplasm
translation
cells regulate ribosomal synthesis by controlling number of active __
as cells become more differentiated, growth slows and require fewer __ for protein prodxn
malignant cells have high __ numbers
PFA analyzes time needed to form platelet based __ plug
would be abnormal in T or __ dz
KS shows spindle cells w __ proliferatio and extravasted RBC
can be a flat M__ lesion or raised hemorrhagic nodule
Adenoca has protuberant __
dysplastic mucosal cells w __ formation
CMV shows U/E
cytomegalic cells w I__
Crypto has nonulcerative inflam and __ clsuters on surface of mucosal cells
E histolytic shows __ shaped ulcerative lesions
T__ contain RBC
UC shows red, friable, graular __
infammatory infiltrate of M/S w CRYPT ABSCESS
genes
ribosomes
ribosome
hemostatic
thrombocytopenia, vWF
BV
maculopapular
mass
glandular
ulcers/erosions
inclusion bodies
basophlic
flask
trophozoite
mucosa
musosa/submucosa
nonoxidative pathways of PPP use T__ to convert G3P and F6P for ATP generation
when R5P is needed, the enzymes work in __ direction
in HF, dec __ stimulates RAAS/SNS leading to increased afterload
Pressure volume loop points D-A is ventricular \_\_ point A-B is isovolumetric \_\_ point B- C is ventricular \_\_ Point C-d is isovolumetric \_\_
Spastic diplegia, abnormal movements, grwoth delay w inc arginine is __ deficiency
used to produce O/U
pt has mild/no hyper__
tx w low __ diet
transketolase
opposite
CO
filling
contraction
ejectin
relaxation
arginase
ornithine, urea
ammonemia
protein
orotic acid is overproduced w excess C__
seen in C/O deficiency
always accompanied w hyper__
high levels of __ confirms CAH
A__ is endometrial tissue in the myometrium
heavy, P__ menstrual bleeding due to endometrial growth in confined space
uterus is enlarged __
dx w H__
L__ is proliferation of myometrial smooth muscle tissue
uterus is __ enlarged
endometrial gland prolif that is greater than stroma indicates ___
hyperplastic growth of endometrial gland/stroma is a __
carbamoyl phosphate
citrullinemia, OTC def
ammonemia
17 hydroxyprogesterone
adenomyosis
painful
uniformly
hysterectomy
leiomyoma
irregularly
endometrial hyperplasia
endometrial polyp
injection in __ quadrant has high probability of damaging SGN
hip drop occurs __ as pt is walking
S/A__ gluteal areas are safest for gluteal infection
AR mutation of \_\_ is Wilson Dz impaired transport of \_\_ w reduced excretion leads to hepatic failure and \_\_ sx tx w \_\_ and trientine or \_\_ to interfere w copper absorption
superomedial
opposite
superolateral/anterolateral
ATP7B Copper neuropsych d-penicillamine Zn
pt w CD and symptoms of easy bruising like large ecchymoses and hemarthrosis indicates __
A/F are NK1 antags for chemo induced vomiting
L__ is THF derivative to prevent toxicity in pt on MTX
use w 5FU, as __ deficient cells have reduced toxicity
C__ is antimetabolite incorporated into DNA for strand termination
G__ is similar, but is not __ phase specific
F__ is used to tx CLL
inhibits DNA__/__/__ and RN reductase
bile acid malabsorption
aprepitant, fosaprepitant
Leucovorin
folate
cetyrabine
Gemcitabine, S
Fludarabine
primase, polymerase, ligase
Dobutamine primarily acts on __ receptor, but also B2/A1
effect is to inc C/I and lower SVR
PDE inhibitor M_ prevent cAMP degredation
R__ is anti-anginal that inhibits inward Na channels
cGMP in heart leads to __ of myosin light chains to relax smooth muscle
blanching at site of NE injection w induration/pallor indicates E__
stimulates A1 receptor w significant __
tx by injecting P__ an alpha blocker
I__ is nonselective beta agonist
B1
chronotropy, inotropy
milirone
ranolazine
dephosphorylation
extravasation
vasoconstriction
phentolamine
isoproterenol
NE predominantly acts on __ receptor, followed by A2 and B1
PAH can be due to __ mutation in pro-apoptotic BMPR2 gene
lac operon has reg gene \_\_ promoter gene \_\_ operator region \_\_ produces lac Z for \_\_ activity lac Y allows for \_\_
lac p region is binding of __ to start transcription
when repressor protein binds to operator, __ is prevented from trxn
in lactose containing media, conformational change in __ protein prevents attachment, allowing for trxn to occur
inactivating
lac I lac P lac O beta galactosidase permease
RNA polymerase
RNA poly
repressor
lac operon is positively regulated by cAMP-CAP binding ___ from promoter
negatively regulated by __ binding to the operator
lac operon requires high concentration of __, which occurs w lactose
__ dec activity of AC, thus levels/trxn is low
Cystic __ and L__ w coarctation of aorta seen in __
due to loss of _ crhomo X
Pulm vein HTN produces pulm interstital __ in interlobular septa
edematous __ of septa and accumulation of fluid
all leads to __ w orthopea
upstream
repressor
cAMP
glucose
hygroma, lymphedema
TS
paternal
edema
widening
Pulmonary edema
AAA due to oxidative stress, VSM apoptosis and chronic __ inflammation
MMP are released and __ ECM components
leads to weakness and expansion that slows O2 __
malignant endothelial proliferation is A__
SHS in kids leads to SIDS, P and low birth weight, __ ear disease, A__ and resp infections
lactose fermenting, gram neg rod that is __ positive is E coli
transmural
degrade
diffusion
angiosarcoma
prematurity, middle, asthma
Aedes mosquito transmits C/D
Chikungunya seen w fever, prominent __ of hands/wrist/ankles, and diffuse macular rash
chikungunya, Dengue fever
polyarthralgias
