Tues Wk 5 Mixed 1 Flashcards

1
Q

acute viral hepatitis has __ infiltrates w ballooning hepatocytes and necrosis w hepatocyte __ resulting in councilman/acidophilic bodies
these are shunken, w nuclear __ and eosinophilic

__ necrosis occurs w IC, complement and plasma proteins

in case control study, choose case/control regardless of __

steatorrhea in somatostatinoma due to dec secretion of __ as well as GI motility

somatostatin analogs O/L prevent release of GH from the AP

use empty can test to isolate S__
most commonly injured due to compression by A/H

A

lymphocytic
apoptosis
fragmentation

fibrinoid

exposure

secretin

octreotide, lantreotide

supraspinatus
acromion, humerus

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2
Q

pancoast syndrome is lung tumor at __ in superior sulcus formed by subclavian vessels
see arm paresthesia/wekaness and atrophy/shoulder pain as __ is involved
can result in __ or spinal cord compression w intervertebral foramina involvement

anterior mediastinal masses T, T, T, Terrible __

absence of HGPRT leads to degradation of __/__ into UA
purine salvage is impaired, thus __ activity must inc to produce purines via de novo pathway

cerebellar hemispheres used for motor planning/coordination of __ extremities via lateral descending system
see ipsilateral D, D and intention tremor

A

apex
brachial plexus
Horner syndrome

thymoma, thyroid cancer, teratoma, lymphoma

guanine, hypoxanthine
PRPP amidotransferase

ipsilateral
dysdiadachokinesia, dysmetria

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3
Q

TG is engulfed and T3/T4 released by __ and secreted from BL border
Iodine __ is binding to tyrosine residues in TG

\_\_ is nL/R4
Flow is \_\_ over \_\_
thus, flow is \_\_ xr4/(nL)
blood flow is directly \_\_ to vessel radius
resistance is \_\_ proportional to radius

T__ is STI and partner must be treated

MAOIs T/S/P prevent deamination of NE/Dopa/Serotonin
used for __ depression and treatment resistant states
look for mood reactivity, __ paralysis and rejection sensitivity w inc appetite/sleep

M__ is A2 antagonist for depression

A

pinocytosis
organification

resistance
pressure/resistance
P1-P2
proportional
inversely

trancylpromine, selegiline, phenelzine
atypical
leaden

mirtazapine

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4
Q

shiga toxins are coded by __ by bacteriophage
B subunit for binding and __
A subunit catalyzes removal of __ residue to preent tRNA binding 60s subunity

__ factor of B anthracis inc cAMP acting as AC
causes edema and phagocyte __
__ factor is protease that causes apoptosis and disruption

B pertussis has __ toxin that disinhibits AC via ADP ribosylation
__ toxin acts as AC to inc cAMP leves

C diff toxin A activates __ for release of cytokines w dirrhea/fluid loss
Toxin B induces actin __ w mucosal death and pseudomembranes

Strep pyo streptolysin O/S damages __ membranes

A

plasmid
internalization
adenine

edema
dissociation
lethal

pertussis
AC

PMN
depolymerization

RBC

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5
Q

do not use __ to tx hypothyroid as short half life and fluctuating sx present

Carotid _ baroreceptors use aortic wall stretch to measure blood pressure
dilation of __
affarent limb travels to medullary centers via __ nerve branch of CN9
results in __ output w dec BP/CO/HR

visceral pleura ends __ above parietal pleura
fluid accumulates in __ recess
perform thoracentesis on 6-8 ribs of __ line
8-10 ribs on __
10-12 ribs of __
always go __ rib

A

lioiodothyronine

sinus
ICA
hering
PNS

2 ribs
costodiaphragmatic
midclavicular
midaxillary
paravertebral
above
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6
Q

superior __ artery (from ECA) and inferior tyroid artery (from thyrocervical trunk) supply thyroid/parathyroid
form triad w __ nerve superior/lateral to thyroid gland
this innervates __ when damaged produces low, hoarse voice and dec pitch
internal laryngeal branch of SLN is __ above vocal folds

Lung adenoca is found __ w clubbing and hypertrophic osteodystrophy
Large cell carcinoma has G/G
see large __ cells in sheets/nest

Nicotinic/muscarinic blockade should indicate __ poisoning
see dec CMAP upon __
will improve w __ stimulation as more Ca is present in presynaptic nerve terminal
found in anaerobic enviro of __ foods

Tetrodotoxin prevents __ release w flaccid sx

A

thyroid
external branch of SLN
cricothyroid
sensory

peripherally
galactorrhea, gynecomastia
polygonal

botulinum
stimulation
rapid
canned

Na

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7
Q

osmotic lax M/P are poorly absorbed and draw water into __
ab pain/distension due to __ bacteria fermenting lactose

__ diarrhea has high electrolytes
fecal water content is high in __ diarrhea

Staph epidermis produces biofilms on __ devices
Strep mutans/sanguinis produces biofilms on _
Viridians strep produces biofilm on __
nontypeable Hib produces biofilms in __
this prevents __ penetration and host defense

IR binds to __ subunits, which activates Beta subunits
this __ IR and then __ residues IRS1/2 w translocation of GLUT4
TNFA/catecholamines, glucagon/GC can phosphorylate __ residues that block tyrosine phosphorylation and downstream signaling

A

Mg citrate, PEG
lumen
colon

secretory
osmotic

prosthetic
dental caries
endocarditis
otitis media
antibiotic

Alpha
autophosphorylates, tyrosine
serine/threonine

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8
Q

dec lung compliance means pressure generated is not __ to distend lungs, thus no gas exchange occurs
edema can __ surfactant and inc surface tension

EPI inc __ BP by stimulating B1/A1 receptors
can dec __ BP at low dose via B2
or inc DBP via __ at high dose

shiga/EHEC toxins injure endothelium of preglomerular __/__ w platelet aggregation and formation of microthrombi

Phagocytosis of IgG/antigen occurs via Fc region on __ to Fc receptors
complement binds at __ area near disulfide bond w 2 molecules of IgM/IgG

light chain is on __ of end

A

sufficient
dilute

systolic
diastolic
A1

arterioles/capillaries

very end
higher

outside

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9
Q

dizygotic twins fertilized by __ sperm
always 2 __/__
Monozygotic formed by single __ and 1 zygote w splitting
always same __
if split at end of 1st week, pts will be mono__ and di__
if earlier, has 2 __/__
later results in 1 _/__

early systolic, high freq clock on 2RIS is __

AT2 dec renin release via __ receptors in short loop
in long loop, can raise __ to inhibit intrarenal baroreceptor
or raise __ to inhibit MD

elevated CK in NMS indicates R__

A
2
chorions/amnions
ovum
sex
chorionic, diamniotic
chorions/amnions
chorion/amnion

bicuspid aortic valve

angiotensin
BP
Na

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10
Q

Rate control of PAF use __/__ blockers
rhythm control uses __ drugs
Sotalol has class 3 and __ effects

R__ is antianginal that blocks inward Na channels in ischemic cardiac myocytes
does block K channels w inc in _ but no TdP risk

T1DM develops w genetic susceptibility and __ w enviro factors
insulitis is due to __ immune response

loss of pain/temp in both hands is S__ dx
syrinx damages ventral __/__
1st order neuron is __
2nd order neuron is __
cross at __ and ascend in LF
3rd order neuron in __ nucleus of thalamus and 4th in primary somatosensory cortex
loss of pain and temp seen 1-2 levels __ lesion

A

BB/CCB
antiarrhythmic
BB

ranolazine, QT interval

irritation
cell mediated

syringomyelia
WC, horn
dorsal root ganglia
dorsal horn
VWC
ventral PL
below
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11
Q

light touch/pressure from __ tract

Catalase pos orgs include N, P, L, A, E, S, S, B
CGD inherited __
infections in L, S, LN and liver
can lead to widespread __ formation

Lecithinase of __ has PC actvity to inc platelet agg and adherence expression

Methylmalonic acidemia is AR defect in __ mutase
results in PA/MA buildup and __ w hypoglycemia w gluco inhibited by OA
FFA metabolism produces __ w AGAP MA and hyperammonemia
sx include H, L, V, RDS
MA/PA levels are __

MCAD is similar but has no __

A

anterior ST

nocardia, pseudo, listeria, aspergillus, e coli, staph, serratia, burkholderia
XLR
lung, skin
granuloma

C perfringens

methylmalonyl CoA
AGAP MA
ketosis
hypotonia, lethargy, vomiting
high 

ketosis

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12
Q

tumor of LA w scattered cells and mucopolysaccharide stroma is __
ball valve effect has __ sx due to MV obstruction
produces large amnts of __ leading to angiogenesis/hemorrhage w hemosiderin deposition
large amnts of __ result in constitutional sx

inc LV diastolic pressure in pt w MS should indicate __ problem

pt w anemia but normal WBC/platelets indicates __ aplasia
due to severe __ of marrow erythroid elements
due to IgG/CD8 against RBC __
always look for T/L
can also result from __ infection
will have anti-B19 __ in serum

Anemia of chronic disease has __ TIBC
uterine fibroids produce __ thus causing Polycythemia

A

cardiac myxoma
positional
VEGF
IL6

aortic valve

pure red cell
hypoplasia
precursors
thymoma/lymphocytic leukemia
parvo
IgM

low (ferritin high)
EPO

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