Friday Wk 5 Mixed 2 Flashcards

1
Q

Clindamycin is B__ while metro is bactericidal

azoles inhibit __ a cyp450 enzyme

lower NNT is __

most chemicals are _ and must be metabolized by p450 monooxygenase
enzyme converts S, A, T to a more soluble form

Fluent aphasia has problems w / language
damage to WA in __ gyrus of left temporal lobe
superior MCA supplies __
inferior MCA supplies __

DCCB SE include HA, flushing, D and __ edema
edema due to dilation of precapillary __ thus inc hydrostatic pressure and fluid leakage
use __/__ to dilate postcapillary venules and dec edema

A

bacteriostatic

14a demethylase

beneficial

procarcinogens
steroids, alcohol, toxins

written/spoken
superior temporal
Broca’s area
wernicke’s area

dizziness, peripheral
arterioles
ACEI/ARB

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2
Q

scurvy leads to fragile __ walls w bruising, periodontal disease and __ follicles
necesary for P/L __ enzyme
if hydroxylation does not occur, __ cannot happen and collagen is weak

women w TS are infertile due to ovarian __
w supplementation and __ they can become preg
spontaneous preg can occur, but has high risk of __ or DS/TS

Kallman syndrome mutation in __/__ gene needed for GnRH neuron movement
see hypogonad and __ w delayed puberty
__ enlarging is first sign of puberty in boys
__ enlarging is first sign in girls

__ is failed vitelline duct obliteration
see painless __
may lead to I__ w ab pain and currant jelly stool
use __ scan to dx, as it has affinity for parietal cells
characteristic for inc uptake in __

A

capillary
hyperkeratotic
hydroxylation
crosslinking

failure
IVF
abortion

KAL1, FGFR1
anosmia
testes
breasts

MD
bleeding
intussception
99Tc pertechnecate
RLQ
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3
Q

failed proper hindgut escent results in __

exogenous intake of _ for 10 days stimulates endometrium to become secretory
w/out P, __ prodxn inc causing vasoconstriction of spiral arteries
inc __ degrades ECM w apoptosis of endometrium
leads to deg of __ layer w menstrual flow

LaPlace law is P= __/__
smaller spheres __ as larger spheres increase
__ counterracts this by dec tension

FSH stimulates sertoli cells to release __ to bind/keep T levels high

OSA can be due to neuromuscular _ of dilator muscles, w airway narrowing
stimulation of __ nerve can protrude the tongue, inc diameter
CANNOT LIGATE __ NERVE AS IT IS MOTOR TO VOCAL CORDS

A

imperforate anus

progesterone
prostaglandin
MMP
functionalis

2T/R
collapse
surfactant

ABG

relaxation
hypoglossal
recurrent laryngeal

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4
Q

chest tube placed into __/__ intercostal space on AA/MA line
goes through S, I muscles and parietal pleura

first part of duodenum located at __ vertebra
second part goes from -
close to _ of pancreas and ampulla of vater
third part goes __ over L3 near aorta/IVC
very close to uncinate process of panc and __ artery
compression can lead to _

BP has __ in inner thighs and flexor regions
separation of /
subepidermal, nonacantholytic __ w IgG/C3 in linear pattern

allergic contact derm has localized erythema and edema and severe __
see S__ w edema bw keratinocytes and lymphocytic perivascular infiltrates

Lymph infiltrate at DE jxn w destruction of epidermal cells is __

A

4th/5th
serratus anterior, intercostal

L1
L1-L3
head
horizontally
SMA
mesenteric ischemia

tense bullae
D/E
blisters

pruritis
spongiosa

LP

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5
Q

bacteria Glycosyltransferase adds __ molecules to growing chain
disruption leads to __ stress
Ureaplasma/Mycoplasma have __ as outer membrane, thus cannot be treated w cell wall drugs

tx H pylori w PPI and C/A and bismuth

tx T gondii w P/S (or clindamycin) and leucovorin
if tx doesnt work, think __ as cause
this is second most common cause of __ lesions w mass effect in HIV
think __ or multiple lesions
type of D___ NHL due EBV
dx w positive EBV __ in CSF

AAT deficiency is autosomal _
produced by __ to protect against proteases
most indiv w def are __ for Z allele
dx w measuring serum AAT __ and genetic testing
leads to panacinar emphysema that destroys __
__ involvement is most concern w cirrhosis/HCC
stains positive for __ and resists diastase

A

glycan
oxidative
cholesterol

clarithromycin, amoxicillin

Pyrimethamine, sulfadiazine

primary B cell lymphoma
ring enhancing
Large
diffuse, large cell
PCR
codomiannt
liver
homozygous
levels
alveolar wall
liver
PAS
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6
Q

w met alkalosis, must check __ and urine chloride
loss of H/Cl via __ secretions leads to inc alkali
loss of Cl impairs _ excretion, exacerbating MA
pt has hypo__ and low urine Cl
correct w volume/Cl by __

Diuretics promote __ retention over time, w H/K loss
leads to MA w high urine __ as diuretics are used
or low urine Cl as it __
correct w __
if does not correct, think B/G syndrome

MC excess leads to Na retetion and __/__ loss
pt has __ and high urine Cl w expanded ECF volume and natriuresis
cannot correct w __ (unresponsive)

infarct of anterior wall leads to __ w/in 5-14 days
myocardium is weakened by __ and PMN/macros
pt gets hemopericardium/__ and hypoTN/shock w death

A
volume status
gastric
HCO3
tension
saline
Na
Cl
stopped
saline
bartman, gitelman

H/K
hypertension
saline

ruptured LV free wall
necrosis
Cardiac tamponade

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7
Q

__ is AR disorder w severe arthritis
due to __ def, allowing it to accumulate in CT of body
see blue black __ in sclera/ear
urine becomes __

high grade CIN has spread beyond lower __ of cervical epithelium
low grade has not and may __

pertussis toxin causes inc __ release, PMN/Lymph destrxn, and inc sensitivity to __

Clozapine/olanzapine have high risk of __

bisphosphonates bind to __ site on bones
inc OC _ and dec recruitment

T__ is PTH analog that stimulates maturation of OB
also inc GI calcium __ and renal reabsorption

use __ in DVT prevention when inpatient
this inc __ to promote anticoag
must monitor __ heparn

A

alkaptonuria
HAD
deposits
black

1/3
regress

insulin
histamine

metabolic syndrome

hydroxyapettite
apoptosis

teriperatide
absorption

heparins
AT3
unfractionated

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8
Q

Use direct thrombin inhibs A/L for HIT
Dabigatran can be used to prevent __ and stoke in Afib

opioids, radiocontrast, vanc can cause mast cell degranulation via __/__
this is IgE __ process

betalactams, sulfonamides can cause IgE __ process

gastric tumor metastasized to ovary is __ tumor
look for __ cells as mucin displaces nucleus
spreads via __ and peritoenal seeding

large, bilobed inclusion like nuclei is __ cell

Gallstone ileus due to __ fistula into ileum
obstructs __ w crampy pain, vomiting/bloating and sx of SBO
can see airfluid bowel loops and air in biliary tree P_ due to retrograde passage of air

MCC of death in Marfan is aortic __ w dissection
second is cardiac failure due to __/__
lens dislocation is __

homocystinuria lens dislocation is __
inherited __

A

argatroban, lepirudin
DVT

PKA/PI3K
independent

dependent

krukenburg
signet ring
lymphatics

RS

cholocytoenteric
ileum
pneumobilia

aneurysm
MVP/AR
UPWARD

DOWNWARD
AR

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9
Q

drug that causes inc SBP/DBP and slowed HR is __ like P/M
baroreceptors in carotid/aortic sinus leads to __ influence on heart to slow conduction

A1 agonist causes vasc smooth msucle \_\_
mydriasis and inc tone of \_\_/\_\_
A2 agonist dec \_\_ mediated BP
dec intraocular pressure and L\_\_
dec \_\_ release and inc platelet agg

abundant eosinophilic cytoplasm w keratinization/pearls and bridges is __
starts as __ dysphagia in esophagus and progresses

L__ is benign esophageal tumor
see __ cells w fibrosis

A

A1 agonist, phenylephrine/metolamine

vagal

contraction
IUS/prostate

CNS
lipolysis
NE

SCC
solid

leiomyoma
spindle

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10
Q

CD has __ lesions
__ appearance of ulcerations/normal tissue
bowel wall __ due to inflammation of all layers
creeping fat w possibility for A/S/F

UC may have P__

A

skip
cobblestone
thickening
abscess, strictures, fistulas

pseudopolyp

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