Tues Wk 4 Mixed Flashcards

1
Q

Ischeic/dilated cardiomyopathy have normal/dec ventricular wall __
ventricular cavity is __ and contractile fxn is __
this is ___ DYSFXN
can be a result of a__

dynamic LVOT obstruction seen in __ cardiomyopathy
inc __ thickening
contractile fxn is normal, but ventricular cavity size is __

HTN HD is ___ DYSFXN
ventricular wall thickness is __
ventricular cavity size is __
contractile fxn is normal

A

thickness
large, dec
systolic
alcohol

hypertrophic
septal
dec

diastolic
inc
dec

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

to differentiate S sapro and epidermidis, must use __ test
Staph aureus also produces __ pigment

F__ is D1 receptor agonist
activates AC to __ arterial beds
renal vasodilation leads to inc renal __ w resulting natri/diuresis
used in HTN __ w ACS, encephalopathy, PE, AKI, aortic dissection etc

androgenetic alopecia occurs at __ areas and vertex
polygenic, along w E, G, HTN, S

BBB is formed by TJ bw nonfenestrated __ endothelial cells to prevent paracellular transport
aka zonulae O__
LDOPA binds __ AA transporter to enter brain

A

novobiocin
yellow

fenoldapam
vasodilate

perfusion
emergency

temporal
Epilepsy, glaucoma, schizophrenia

capillary
occuludentes
neutral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fenestrae are small pores that allow free __ exchnage bw IV/EV spaces
ie I/Renal T/endocrine gland capillaries

H__ are assc w BM
D__ are in SS of epidermis

BBB only allows T__ transport via carrier/diffusion mechs

tumor composed of uniform shape/size of cells in island is __
eosinophilic cytosplasm w round nuclei and granules contain __ products
come from N__ cells

A

fluid
intestine, tubule

hemidesmosomes
desmosomes

transcellular

carcinoid
secretory
neuroendocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

__ def has angular stomatitis, cheilitis, glossitis, seborrheic derm, eye changes and anemia
FMN is used in complex __ of ETC
FAD used in __ dehydro and complex __

Zinc finger is a DNA _ motif
AA bound to __ via cysteine/histidine linkages

HDAg is replication defective as it must be coated by __ to penetrate the hepatocyte

Dysthymia is depressed mood for greater than __ yrs w 2 other depressive sx

Colchicine inhibits __ dependent fxns
ie C/P/D as well as dec LB4 prodxn

A

Riboflavin
1
succinate
2

binding
zinc

HBsAg

2

cytoskeleton
chemotaxis, phagocytosis, degranulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Menopause is cessation of menses for __ mnths
caused by exhaustion of ovarian __
FSH then inc due to lack of __ released by follicle

Aspiration of gastric contents presents w __ w in hours of event
resolves w out use of __

Vitelline vein becomes __ system
Cardinal vein becomes __ venous circ
Central lines placed into __ or __ to SVC

A

12
follicle
inhibin

hours
antibiotics

portal
systemic
IJV, subclavian vein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

vertical diplopia is due to __ nerve palsy
eye will be extorted and __
normally allows for intorsion and __ of gaze
impaired __ gaze w adducted eye
chin is tucked and tilted __ from affected eye

Median nerve and __ artery run through medial supracondylar region

once Shigella enters M cells, lyses __ and enters cytosolic compartment
spreads to adjacent cells via host cell __ polymerization

Aminoglycosides bind __ rRNA portion of 30s subunit

A
trochlear
elevated
depression
vertical
away

brachial

vacuole
actin

16s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Heteroplasmy is due to variability in __ as mitochondira are randomly distributed bw daughter cells
this explains varying __ of fx in mitochondrial dz

accessory conduction pathways is __ syndrome
short __ w delta wave and wide __
due to accessory pathway __ the ventricles
leads to recurrent __

insulin resistance dec __ effect of insulin, thus more FFA are released
LDL/HDL does __ contribute to insulin resistance

A

mitosis
severity

WPW
PR, QRS complex
preexciting
PSVT

antilipolytic
not

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

cystic cavity w surrounding gliosis in brain indicates old __
releases __ enzymes w degradation of tissue in region
phagocytes migrate and remove __, as astrocytes proliferate to form scar
process also seen in __/_ infection

Hemorrhagic infarct seen in areas of __ blood supply like lung

uptake of Iodide against conc gradient occurs via __ symptorer via TSH
Iodine reacts w tyrosine residues on __ to form MIT/DIT called iodination
coupling then occurs to form __/__
along w conversion of iodide to iodine, this processes occur via __ enzyme

A

cerebral infarct
lysosomal
cavity
bacterial/fungal

dual

Na-I
TG
T4, T3
TPO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

__ is antipsychotic most likely to cause hyperprolactinemia
inhibits __/__ receptors

Glycogen synthase is active in the __ form
Insulin bins to IR which is __ TK
activates IRS1 to stimulate __ to alter DNA synthesis/growth
activates __ kinase to transport GLUT4 to CM and glycogen/fat synthesis

PKA activates glycogen __ via activation of glycogen phosphorylase kinase

Ziduvidine has __ group in place of hydroxyl group on 3’ end of thymidine
this prevents chain __ by blocking phosphodiesterase formation

anthracyclines like D/D intercalate into bases causing defective base pairing

A

risperadone
D1/D2

dephosphorylated
intrinsic
MAP kinase
PI3K

phosphorylase

azido
elongation

doxorubicin, danaurubicin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

yolk sac form __ that extends to UG sinus
upper part forms b__
allantois forms u_ to connect bladder/yolk sac
complete failed urachus obliteration leads to patent ___ w straw colored urine from umbilicus

failure to close distal urachus leads to urachal S__
presents w periumbilical _ and purulent discharge
failed central portion to obliterate leads to urachal __

SE of NDCCB include C, slowing of __ (AV block)
avoid in pt w LV __ dysfxn due to neg inotropic effect

A

allantois
bladder
urachus
urachus

sinus
tenderness
cyst

constipation, sinus rate
systolic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

cricothyrotomy
skin, __ cervical fascia w subq fat and platysma, investing/pretracheal __ cervical fascia and cricothyroid membrane
allows tube to enter C/T cartilage

Deep cervical fascia
Investing- wraps neck like __ enclosing deep parts
includes S, T, S
Submaxillary/__ gland

Pretracheal- anterior portion, blends lterally w __ sheath
contains __ of neck

Prevertebral surrounds __ and includes muscles of spin

Carotid sheath lies lateral to retro__ space and deep to SCM
includes __ artery, __ vein, __ nerve

A

superficial, deep
cricoid, thyroid

collar
SCM, trapezius, scalenes
parotid

carotid
viscera

vertebral column

pharyngeal
Carotid, IJ, vagus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

seconary vasospasm of SAH produces cerebral __ w HA and focal deficits
due to impaired brain __
use transcranial __

prevent w __ a CCB

A

ischemia
autoregulation
doppler

nimodipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly