Friday Wk 5 Mixed Flashcards

1
Q

Medullary thyroid cancer is malignancy of __ cells

Down syndrome assc D/H/I/T/C
Pyloric stenosis is __ emesis

__ is a descriptive study that tracks pt w known condition and how they respond to tx

Tb is arranged in __ due to presence of cord factor
formed of two mycolic acid molecules bound to __
this glycolipid prevents __ mediated destrxn
crystalline monolayer drives formation of __

A1 receptors, AT2 receptors, Oxytocin, vasopressin receptors all use __ second messenger system

cGMP causes vasc smooth muscle __

A

PARAFOLLICULAR C cells

Duodenal atresia, Hirschprung, Imperforate anus, TEF, celiac
NONBILIOUS

Case series

serpentine cords
trehalose
macrophage
caseating granulomas

IP3

relaxation

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2
Q

__ dz is AR lysosomal disorder
abnormality in protein __ due to impaired phosphotransferase enzyme
cannot phosphorylate __ residues, leading to them being stuck in the cytostol
cannot act as __ for degredation inside lysosomes, thus debris accumulates in lysosomes
sx include Developmental delay, FtT and __ facial features w corneal clouding

PNS fibers innervate iris __ and ciliary muscle
thus, lesion leads to __ pupil

protamine binds to __ to form inactive complex

warfarin overdose should be treated w __ to cause coag as well as FFP

Sjogren syndrome in __ w dry eyes/mout, dental carries, large salivary glands
Anti-Ro __ and Anti-La __ ab

A
Inclusion body
trafficing
mannose
catalases
coarse

sphincter
dilated

heparin

PCC

old women
SSA, SSB

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3
Q

bilateral parotid enlargement, eroded dental enamel, HYPOK/HYPOCl, met alk and calluses on hands is __
also see hypo__ and tachycardia
BMI is __
tx w CBT and SSRI __

BMI<18.5 is __ due to intense fear of weight gain/body shape
tx w CBT and O__

Binge eating disorder tx w CBT, SSRI and L, T

Secretin produced by duodenal __ cells due to high Acid levels
panc secretion is __ w Na/K normal
high _ and low _ as secretin increases

Herpes encephalitis has _/__ as cell type
virus meningitis has __ glucose, __ protein
fungal has __ glucose, __ protein
GBS has CSF __ elevation w normal cell counts

A

BN
tension
normal
fluoxetine

AN
olanzapine

lisdexamphetamine, topiramate

S cells
isotonic
HCO3, Cl

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4
Q

__ Ca channels open as funny Na channels make the node more positive
then __ Ca channels open
slow response tissues have AP that moves __
Class 4 antiarrhythmics prefer __ tissue by blocking L type and T type Ca channels
works to __ intracellular calcium to downregulate coupling in cardiac myocytes

other signs of MCA stroke include A and spatial neglect of contralateral side (pareital lobe)
gaze devation __ side of stroke
may have __ due to Left MCA involvement of speech areas

Basilar artery occlusion affects __ CS/CB tracts
see Q__ and facial weakness/dysarthria w horizontal gaze palsy

AICA leads to __ syndrome
see ipsi loss of __ on face due to TG nucleus
ipsi face weakness due to __ nucleus
ipsi hearing loss by __ nucleus
contralateral loss of __ due to LST tract, and ataxia

Lesion of Acom has __

A
T type
L type
slower
slow response
dec

anosognosia, toward
aphasia

pontine
quadriplegia

lateral pontine
pain/temp
facial
cochlear
pain/temp

bitemporal hemianopsia

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5
Q

Aspergilloma is __ in old cavity
Invasive pulm aspergillomas occur in __/__ pt w cough, chest pain, hemoptysis

use old aminoglycoside S__ for Tb, tularemia, plaque
resistance due to altered __ subunits, modifying enzymes, and mutated __

__ repairs depurination, alkylation, oxidation, deamination
deamination of C, A, G forms U, H, X
if not corrected, leads to __
__ recgonizes abnormal base and cleaves it to form AP site
__ cleaves 5’ end and lyase extracts AP site
__ fills in gap, and nick sealed by ligase

S pneumo capsule swells w __ as anti-capsular antibodies/methylene blue is added (Quellung rxn)
also has __ protease, adhesins, and P__ to form pores

A

colonization
neutropenic/Immunosuppressed

streptomycin
ribosomal
porin

BER
uracil, hypoxanthine, xanthine
carcinogenesis
Glycosylase
endonuclease
DNA poly

halo
IgA
pneumolysin

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6
Q

Estrogen leads to gynecomastia by stimulating ductal epithelial __
Antiandrogens F/B block testosterone receptor
spironolactone dec __ synthesis and inhibits receptor
Ketoconazole dec __ more than estrogen synthesis
C__ inhibits T receptor

aldosterone has __/__ effect on heart to cause deterioration of LV fxn

activated __ macros in response to Tb release IL12 to cause Th1 response
IFNG/TNFa then released to recruit __/__

acetylcholinesterase activity dec at __ temp

Atopic dermatitis has __ skewed respionse

Acute hypersensitivity pneumo is due to serum IgG antibodies that precipitate w __/__ antigens in dust
cause alveolitis/bronchiolitis via __ deposition in vessel walls (type 3 HS rxn)

A
hyperplasia
flutamide, bicalutamide
testosterone
androgen
cimetidine

autocrine/paracrine

epitheliod
macros/lymphocytes

cold
Th2

bacterial/funga
immune complex/complement

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7
Q

INSOMNIA, NIGHTMARES, AVOIDANCE, dissociative dx and detachment is __
often have __ mood and flashbacks

__ is squamous cell debris forming pearly mass behind TM
due to __ pressure of middle ear w retraction pockets
secondary can occur as squamous epithelium __ to middle ear
painless _ is sx
may produce __ enzymes that erode ossicles w CHL
can erode vestibular apparatus/facial nerve w /

bluish/black gelatinous material behind TM after hemorrhage is __ (not actually cholesterol/lipid)

__ is most common malig of ear canal

QRS duration is __ uring exercise at heart rate is inc

A

PTSD
negative

cholesteoma
neg
migrates
otorrhea
lytic
vertigo/facial paralysis

cholesterol granuloma

SCC

dec

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8
Q

longer QRS w high HR indicates strong __ of Class 1C
bind to fast __ for phase 0 depolarization of myocytes to block inward movement
prolongs QRS w little effect on __

Digoxin can cause ST segment __ during exercise test
also dec maximal __

Class 3 antiarrhythmics have _ use dependence, thus QT is prolonged at low HR

Neg chrono meds- __/__ blockers
D/A/S and CHOLINERGIC meds
when used together, can dec HR w subsequent __

nifedipine is vasodilator and causes REFLEX ___

thiazolidinediones upregulate __/__ to inc FA oxidation/glucose uptake
results in inc fat __ and dec FFA

A

use dependence
Na channels
QT interval

depression
HR

reverse

BB/NDCCB
digoxin, amiodarone, sotalol
hypoTN

tachycardia

adipnectin, GLUT4
mass

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9
Q

copper is absorbed in S/D and bound to __ to go to L
incorporated w __ into ceruloplasmin to plasma
unused copper is secreted into __ and excreted

in normal pt, CFTR aids in prodxn of __ sweat
in CF pt, lots of / is lost in sweat
thus, must have __ supplementation

Lightning strike death due to __ or resp failure
look for R/bone fractures, cataracts, PN and __ dysfxn
burns are __ as lightning goes over surface into ground

infants have large //_ that leads to inc brain movement
shaking results in tearing of __ and SDH
look for __ SDH and retinal hemorrhage/posterior rib fractures to suggest abuse

A

stomach/duodenum
albumin
a2 globulin
bile

hypotonic
Na/Cl
salt

arrhythmias
rhabdo
autonomic
superficial

head, brain water, subarachnoid space
bridging cerebral veins
acute on chronic

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10
Q

splinter hemorrhages/janeway lesion due to __ from subacute bacterial endocarditis

hypothyroid results in high __/__ as T4 falls
can lead to __ due to positive stimulation

pt w elevated painful rash on groin/face/extremities has __
NME coalesce to form large __ and central clearing
look for recent __ dx and Gi sx w high glucagon

__ def has skin rash around body orifices w HYPOGONAD, lack of taste/smell and night blindness
look for absence of ___

__ LN located on bowel wall
__ LN along arterial areas, intermediate nodes around _ vessels
lymph proximal to dentate line goes to __/__ LN
upper/superior middle rectum drains to __ LN into IMLN
middle/lower rectum goes to __ LN to II LN
distal to the dentate line drains to __ LN

A

microemboli

glucagonoma
plaques
Diabetes

Zn
Diabetes dx

epicolic
paracolic
mesenteric
inferior mesenteric
internal iliac

superior rectal

middle rectal
inguinal

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11
Q

Left/right colic arteries drain __ descending/ascending colon

GBS due to molecular __ as infection contains ganglioside like substance
Ab/T cells react w M/S w endoneurial inflam infiltrate

WH syndrome is damage to AH cells w __ gene mutation
weakness is __ and occurs in childhood

watershed necrosis is __ encephalopathy
usually due to __ causing global cerebral ischemia
pyramidal cells of __ and perkinje cells of __ are most vulnerable
w progression, areas of _ become infarcted
appear as bilateral __ shaped strips of necrosis over cerebral convexity adjacent to long cerebra fissure

Hypertensive arteriolar sclerosis due to __ and produces lacunar infarcts

HTN enceph has HA, V, confusion w brain / in gray/white matter

lobar consolidation is ___

A

upper

mimicry
myelin, schwann cells

SMN1
proximal

hypoxic ischemic
hypoTN
hippocampus, cerebellum
watersheds
wedge

HTN occlusion

edema/hemorrhage

cerebral amyloid angiopathy

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12
Q

centrocytes/centroblasts indicates __
see packed __ obscuring normal LN

NMYC can be __/__

A

follicular lymphoma
follicles

neuroblastoma/SCLC

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