Friday Wk 5 Mixed Flashcards
Medullary thyroid cancer is malignancy of __ cells
Down syndrome assc D/H/I/T/C
Pyloric stenosis is __ emesis
__ is a descriptive study that tracks pt w known condition and how they respond to tx
Tb is arranged in __ due to presence of cord factor
formed of two mycolic acid molecules bound to __
this glycolipid prevents __ mediated destrxn
crystalline monolayer drives formation of __
A1 receptors, AT2 receptors, Oxytocin, vasopressin receptors all use __ second messenger system
cGMP causes vasc smooth muscle __
PARAFOLLICULAR C cells
Duodenal atresia, Hirschprung, Imperforate anus, TEF, celiac
NONBILIOUS
Case series
serpentine cords
trehalose
macrophage
caseating granulomas
IP3
relaxation
__ dz is AR lysosomal disorder
abnormality in protein __ due to impaired phosphotransferase enzyme
cannot phosphorylate __ residues, leading to them being stuck in the cytostol
cannot act as __ for degredation inside lysosomes, thus debris accumulates in lysosomes
sx include Developmental delay, FtT and __ facial features w corneal clouding
PNS fibers innervate iris __ and ciliary muscle
thus, lesion leads to __ pupil
protamine binds to __ to form inactive complex
warfarin overdose should be treated w __ to cause coag as well as FFP
Sjogren syndrome in __ w dry eyes/mout, dental carries, large salivary glands
Anti-Ro __ and Anti-La __ ab
Inclusion body trafficing mannose catalases coarse
sphincter
dilated
heparin
PCC
old women
SSA, SSB
bilateral parotid enlargement, eroded dental enamel, HYPOK/HYPOCl, met alk and calluses on hands is __
also see hypo__ and tachycardia
BMI is __
tx w CBT and SSRI __
BMI<18.5 is __ due to intense fear of weight gain/body shape
tx w CBT and O__
Binge eating disorder tx w CBT, SSRI and L, T
Secretin produced by duodenal __ cells due to high Acid levels
panc secretion is __ w Na/K normal
high _ and low _ as secretin increases
Herpes encephalitis has _/__ as cell type
virus meningitis has __ glucose, __ protein
fungal has __ glucose, __ protein
GBS has CSF __ elevation w normal cell counts
BN
tension
normal
fluoxetine
AN
olanzapine
lisdexamphetamine, topiramate
S cells
isotonic
HCO3, Cl
__ Ca channels open as funny Na channels make the node more positive
then __ Ca channels open
slow response tissues have AP that moves __
Class 4 antiarrhythmics prefer __ tissue by blocking L type and T type Ca channels
works to __ intracellular calcium to downregulate coupling in cardiac myocytes
other signs of MCA stroke include A and spatial neglect of contralateral side (pareital lobe)
gaze devation __ side of stroke
may have __ due to Left MCA involvement of speech areas
Basilar artery occlusion affects __ CS/CB tracts
see Q__ and facial weakness/dysarthria w horizontal gaze palsy
AICA leads to __ syndrome
see ipsi loss of __ on face due to TG nucleus
ipsi face weakness due to __ nucleus
ipsi hearing loss by __ nucleus
contralateral loss of __ due to LST tract, and ataxia
Lesion of Acom has __
T type L type slower slow response dec
anosognosia, toward
aphasia
pontine
quadriplegia
lateral pontine pain/temp facial cochlear pain/temp
bitemporal hemianopsia
Aspergilloma is __ in old cavity
Invasive pulm aspergillomas occur in __/__ pt w cough, chest pain, hemoptysis
use old aminoglycoside S__ for Tb, tularemia, plaque
resistance due to altered __ subunits, modifying enzymes, and mutated __
__ repairs depurination, alkylation, oxidation, deamination
deamination of C, A, G forms U, H, X
if not corrected, leads to __
__ recgonizes abnormal base and cleaves it to form AP site
__ cleaves 5’ end and lyase extracts AP site
__ fills in gap, and nick sealed by ligase
S pneumo capsule swells w __ as anti-capsular antibodies/methylene blue is added (Quellung rxn)
also has __ protease, adhesins, and P__ to form pores
colonization
neutropenic/Immunosuppressed
streptomycin
ribosomal
porin
BER uracil, hypoxanthine, xanthine carcinogenesis Glycosylase endonuclease DNA poly
halo
IgA
pneumolysin
Estrogen leads to gynecomastia by stimulating ductal epithelial __
Antiandrogens F/B block testosterone receptor
spironolactone dec __ synthesis and inhibits receptor
Ketoconazole dec __ more than estrogen synthesis
C__ inhibits T receptor
aldosterone has __/__ effect on heart to cause deterioration of LV fxn
activated __ macros in response to Tb release IL12 to cause Th1 response
IFNG/TNFa then released to recruit __/__
acetylcholinesterase activity dec at __ temp
Atopic dermatitis has __ skewed respionse
Acute hypersensitivity pneumo is due to serum IgG antibodies that precipitate w __/__ antigens in dust
cause alveolitis/bronchiolitis via __ deposition in vessel walls (type 3 HS rxn)
hyperplasia flutamide, bicalutamide testosterone androgen cimetidine
autocrine/paracrine
epitheliod
macros/lymphocytes
cold
Th2
bacterial/funga
immune complex/complement
INSOMNIA, NIGHTMARES, AVOIDANCE, dissociative dx and detachment is __
often have __ mood and flashbacks
__ is squamous cell debris forming pearly mass behind TM
due to __ pressure of middle ear w retraction pockets
secondary can occur as squamous epithelium __ to middle ear
painless _ is sx
may produce __ enzymes that erode ossicles w CHL
can erode vestibular apparatus/facial nerve w /
bluish/black gelatinous material behind TM after hemorrhage is __ (not actually cholesterol/lipid)
__ is most common malig of ear canal
QRS duration is __ uring exercise at heart rate is inc
PTSD
negative
cholesteoma neg migrates otorrhea lytic vertigo/facial paralysis
cholesterol granuloma
SCC
dec
longer QRS w high HR indicates strong __ of Class 1C
bind to fast __ for phase 0 depolarization of myocytes to block inward movement
prolongs QRS w little effect on __
Digoxin can cause ST segment __ during exercise test
also dec maximal __
Class 3 antiarrhythmics have _ use dependence, thus QT is prolonged at low HR
Neg chrono meds- __/__ blockers
D/A/S and CHOLINERGIC meds
when used together, can dec HR w subsequent __
nifedipine is vasodilator and causes REFLEX ___
thiazolidinediones upregulate __/__ to inc FA oxidation/glucose uptake
results in inc fat __ and dec FFA
use dependence
Na channels
QT interval
depression
HR
reverse
BB/NDCCB
digoxin, amiodarone, sotalol
hypoTN
tachycardia
adipnectin, GLUT4
mass
copper is absorbed in S/D and bound to __ to go to L
incorporated w __ into ceruloplasmin to plasma
unused copper is secreted into __ and excreted
in normal pt, CFTR aids in prodxn of __ sweat
in CF pt, lots of / is lost in sweat
thus, must have __ supplementation
Lightning strike death due to __ or resp failure
look for R/bone fractures, cataracts, PN and __ dysfxn
burns are __ as lightning goes over surface into ground
infants have large //_ that leads to inc brain movement
shaking results in tearing of __ and SDH
look for __ SDH and retinal hemorrhage/posterior rib fractures to suggest abuse
stomach/duodenum
albumin
a2 globulin
bile
hypotonic
Na/Cl
salt
arrhythmias
rhabdo
autonomic
superficial
head, brain water, subarachnoid space
bridging cerebral veins
acute on chronic
splinter hemorrhages/janeway lesion due to __ from subacute bacterial endocarditis
hypothyroid results in high __/__ as T4 falls
can lead to __ due to positive stimulation
pt w elevated painful rash on groin/face/extremities has __
NME coalesce to form large __ and central clearing
look for recent __ dx and Gi sx w high glucagon
__ def has skin rash around body orifices w HYPOGONAD, lack of taste/smell and night blindness
look for absence of ___
__ LN located on bowel wall
__ LN along arterial areas, intermediate nodes around _ vessels
lymph proximal to dentate line goes to __/__ LN
upper/superior middle rectum drains to __ LN into IMLN
middle/lower rectum goes to __ LN to II LN
distal to the dentate line drains to __ LN
microemboli
glucagonoma
plaques
Diabetes
Zn
Diabetes dx
epicolic paracolic mesenteric inferior mesenteric internal iliac
superior rectal
middle rectal
inguinal
Left/right colic arteries drain __ descending/ascending colon
GBS due to molecular __ as infection contains ganglioside like substance
Ab/T cells react w M/S w endoneurial inflam infiltrate
WH syndrome is damage to AH cells w __ gene mutation
weakness is __ and occurs in childhood
watershed necrosis is __ encephalopathy
usually due to __ causing global cerebral ischemia
pyramidal cells of __ and perkinje cells of __ are most vulnerable
w progression, areas of _ become infarcted
appear as bilateral __ shaped strips of necrosis over cerebral convexity adjacent to long cerebra fissure
Hypertensive arteriolar sclerosis due to __ and produces lacunar infarcts
HTN enceph has HA, V, confusion w brain / in gray/white matter
lobar consolidation is ___
upper
mimicry
myelin, schwann cells
SMN1
proximal
hypoxic ischemic hypoTN hippocampus, cerebellum watersheds wedge
HTN occlusion
edema/hemorrhage
cerebral amyloid angiopathy
centrocytes/centroblasts indicates __
see packed __ obscuring normal LN
NMYC can be __/__
follicular lymphoma
follicles
neuroblastoma/SCLC