Monday Wk 6 Mixed 1 Flashcards
AML has inc P__
inversion 16 is M4Eo __ subtype of AML
closer r value is to margins in correlation graph, __ the association
fibrates inhibit __ which dec cholesterol solubility
thus, can promote __ formation
Omega 3 FA inc BA __, dec cholsterol saturation, and inc gallbladder __
recurrent PNA/gastro infections, hx of autoimmune conditions, anaphylaxis following transfusion has __
can have _ develop against IgA antigens, thus leading to anaphylaxis w exposure
collagen fibers are / and form triple helix in RER
tropocollagen molecules __ assemble to form triple helix
promyelocytes
eosinophilic
stronger
7a hydroxlyase
gallstone
prodxn, mobility
IgA deficiency
IgE
hydroxylated/glycosylated
spontaneously
Alzheimers has dec Ach due to deficiency in C__
NMDA receptors are __ in huntington dz
hemolysis/frequent RBC transfusions can lead to __ overload (hemosiderinosis)
Fe accumulates in __ and appears brown/yellow
in liver, accumulates in _ cells
O2 from lungs enters systemic circ at O2 conc slightly __ than alveolar due to mixing w __ circ and Thebesian veins of heart
normal A-a O2 gradient is less than __
active skeletal muscle in O2 _ and CO2 prodxn
countered by inc _ and SM perfusion
venous O2 will be __, while CO2 will be inc
perfusion/ventilation of alveoli will be normal, thus __ should not change
choline acetyltransferase
downregulated
Fe
macrophages
Kupffer
less
bronchial
15
consumption
CO
lower
physiologic dead space
Type A drug rxn is __ such as gastritis w NSAID
Type B is all __
can have __ sensitivity such as tinnitus after single use of aspirin
due to altered /
_ drug rxn is unexpected, such as HA in G6PD def
_ is due to immune system
_ mimics immune rxn, but via non immunologic process
B12 supplementation cause inc __ w reticulocytes released
peak at __, while Hb rises much slower
Tb reactivates to __ due to dec lymph flow, or inc O2 tension
erosion into pulm vessels can cause __ and heme dissemination
Gohn __ is focal Tb in lower lungs
w focus in place, spreads via __ to hilar LN and forms ghon compex
predictable unpredictable exaggerated metabolism/sensitivity idiosyncratic immunologic pseudoallergenic
erythropoeisis
1 w
upper lobes
hemoptysis
focus
lymphatics
anterior compartment of leg is __ nerve w _ artery/vein
lateral is __ nerve
deep is __ nerve, w __/__ artery/vein
fascia is inelastic, thus when pressure inc, severe / can develop ACS
Staph/Bacillus cereus form heat stable __ prior to exposure
other causes of vomiting/diarrhea are due to __ formed after exposure
ARPKD due to __ mutation
codes for __
sx include renal _ and nephromegaly, HTN after months
see bilateral, enlarged, echogenic __ on US
may present w __ fibrosis
avoid __ in pts w systolic cardiac dysfxn
deep peroneal, anterior tibial
superficial peroneal
tibial, peroneal/posterior tibial
pain/ischemia
enterotoxin
exotoxin
PKHD1 fibrocystin insufficiency kidneys hepatic
NDCCB
lactase nonpersistence has declining __ expression in adulthood
bacteria can ferment lactose to __ that acidify the stool
H2 gas is released, thus breath content is __
high lactate in stool __ osmolarity w osmotic diarrhea
T__ is SSRI that also inhibs postsynaptic serotonin receptors to tx insomnia
rare SE of __ worse w other predisposing conditions MM/SCD
also affects / for SE
M/R/I/drugs like I/H and CTD can lead to pericardial tamponade
Becks triad is _
ECG shows low __ complexes w electrical alternans
chest xray shows __ w clear lungs
lactase
short chain FA
higher
inc
trazodone
priapism
A1/H1
malignancy/radiation infection, isoniazid, hydralazine hypoTN, distended neck veins, muffled heart sounds voltage bottle shaped heart
Testosterone needed for S and P
DHT needed for growth of _ and amplifies testosterone effect
5AR type 1 found in _
5AR type 2 found in _, and if deficient, results in male pseudohermaphroditism
such as small __ w hypospadias
Alanine helps remove excess __ in body
transaminated to __ via AKG (as all transams are)
this forms __ which is degraded to ammonia/AKG
ammonia goes to __ cycle and is excreted in urine
mitochondrial dysfxn affects / first due to high metabolic demand
see M w lactic acidosis and N
consanguineous families inc incidence of __ diseases
calcineurin inhibs cause dose dependent renal _ w tubular cell damage
metabolized by __ isoenzymes
spermatogenesis, puberty prostate skin gonads phallus
nitrogen
pyruvate
glutamate
urea
muscles/CNS
myopathy, neuropathy
vasoconstriction
CYP3A4
Bile acid binding resin SE include __ upset w nutrient probs and inc __ levels
Glyburide/glimepiride are __ and thus inc risk of hypogly
glipizide is short acting, thus has __
radiodensity of fat is __ than water
in TSC, may have __ of brain w seizures/cog dysfxn ,cardiac rhabdomyomas, facial __ and ash leaf patches
Leptomeningeal capillary venous malformation seen in __
cerebellar hemangioblastomas, retinal hemangiomas, liver cysts seen in __
stasis in preg due to __ and compression of vessels
inc in Factor //_ and vWF and fibrinogen
w endothelial damage, pt is at high risk of __
look for fever, ab pain, and no response to _
GI, TG
long acting
less risk
less
hamartomas
angiofibromas
sturge weber
vHL
venous dilation
7, 8, 10
ovarian vessel throbmosis
antibiotics
transtentorial uncal herniation results in __ palsy initially
w midbrain/upper pons involvement, leads to midposition/__ pupils
damage to brainstem at/below red nucleus leads to __ posturing
due to extensor predominance of __ tract (which is never inhib)
lesion above red nucleus (ie cerebral hemispheres) inhibits _ of rubrospinal flexor tract, thus flexion predominates (decorticate)
CRAO due to thromboembolism of __ artery
dec blood supply to __ which branches to retinal artery
__ presents w fever, malaise, ab pain, sore throat
look for red pharynx and grey __ w strawberry tongue (inflamed papillae)
rash starts on body w __ appearance then generalizes
then forms __ like rash w flushed cheeks w circumoral pallor
CN3 fixed decerebrate vestibulospinal repression
internal carotid
ophthalmic
scarlet fever
exudate
boiled lobster
sandpaper
__ are large cells w abundant basophilic cytoplasm
see folded/bilobed __
AUER RODS STAIN FOR __
TdT only present in __
pain, itching, rectal bleeding w ULCERATIVE mass is __
RPGN due to M, P, M that migrate to BS and secrete _
fibroblasts are recruited and release __ and crescents become sclerotic
acute synovitis w fever/leukocytosis is emergency and requires __
serum uric acid may be __ during acute gout attack
LEGIONELLA HAS __ appearance on XRAY
myeloblasts
nuclei
PEROXIDASE
lymphoblasts
HPV
monocytes, glomerular parietal cells, macrophages
fibrin
collagen
immediate arthocentesis
normal
lobar
Glomerular filtration barrier has fenestrated __ w GBM and podocytes
size selectivity is dependent on __ in GBM/slit diaphragm
charge selectivity depends on anions like __ to repel neg molecules
GPF from T cells causes inc _ of neg charged plasma proteins w selective albuminuria
tubular proteinuria only occurs when __ fxn is disrupted
endothelium
pores
heparan sulfate
filtration
proximal tubule
