Thurs Wk 6 Mixed 2 Flashcards
Deliver bad news w SPIKES
Hb carries CO2 as __
remainder of CO2 carried as __ in blood
CA forms __ which is converted to HCO3/H
HCO3 leaves RBC to plasma in exchange for __
PCT causes __ due to accumulating porphyrinogens that react w O2 on exposure to UV light
usually occurs w A/S/H/H
see / on sun exposed areas
Topo 1 makes __ nicks to relieve neg supercoiling
Topo 2 makes ds breaks to relieve / supercoiling
E/P inhibit Topo 2 action to resolve breaks
Etoposide used for / cancers
Podophyllin for __
set the stage
perception, invitation, knowledge, empathize, strategy
carbamate
HCO3
H2CO3
Cl
PHOTOSENSITIVITY
alcohol, smoking, HepC, HIV
vesicles/blisters
single stranded
pos/neg
testicular, SCLC
genital warts
Primary CNS lymphoma is dense, uniform atypical __
usually type of __ positive for CD20/CD79a
assc w _ virus
Staph aureus is carried in humans in __
lesion of prefrontal cortex leads to inappropriate / and poor prob solving skills
__/__ also seen
__ dementia presents w early personality/behavior changes and problems w speech
onset is __ than AD
see __ bodies w microtubule Tau
inherited __
initial sx of AD is loss of __ due to damage to hippocampus
__ is major VD element in small coronary arterioles
__ is primary VD of large arteries/prearterioles
stimulated by N, P, T, H, B, E, S
at rest, coronary arteries extract __ O2 possible
thus, if O2 demand increases, higher __ is needed
lymphocytes
DLBCL
EBV
anterior nares
behavior/personality incontinence/gait probs frontotemporal earlier PICK AD
memory loss
Adenosine
NO
NT, platelets, thrombin, histamine, bradykinin, endothelin, serotonin
as much
BLOOD FLOW
Uncontrolled __ causes precapillary endothelial dyfxn w leakage of plasma
see __ necrosis w flame shaped hemorrhages and visual loss
look for C, A and cotton wool spots
acute angle glaucoma has _ of optic disc and affarent pupillary defect
think __ abscess in pt w immunosuppression, fever, flank pain and difficulty walking
pain exacerbated by __ via extension
PCL arises from __ condyle to instert on posterior tibia
ACL arises from __ condyle to insert on anterior tibia
at tibial plateau, ACL is __
HTN
fibrinoid
copper/silver wiring, av nicking
cupping
psoas
streching the psoas
medial femoral
lateral femoral
anterior
myocardial __ is state of chronic myocardial ischemia w metabolism/fxn reduced due to lack of BF
prevents myocardial __
decreased expression/org of / proteins, adrenergic control and Ca responsiveness
dec __ and LV systolic dysfxn that improves upon restoration of BF
Ischemic __ occurs when repetitive episodes of MI w reperfusion protect myocardium from subsequent ischemia
antigenic __ is responsible for pandemics/epidemics
produces __ human to human transmission
Cholinergic effecs on nicotinic receptors include M, P, F
Organophosphates are __ inhibitors
tx w __ to compete w Ach at muscarinic receptors
__ can tx both muscarinic/nicotinic effects
hibernation
necrosis
cytosolic/contractile
CO
preconditioning
SHIFT
sustained
muscle weakness, paralysis, fasciculations
cholinesterase
Atropine
PRALIDOXIME
Gas gangrene due to __
produces gas/crepitus that is __ on Xray
can also produce late onset __ from food poisoning
spores germinate to release __
RA tissue inflammation causes release of __ that is converted to citrulline
this alters protein __ which becomes antigen for response
C tetani is only found in __ where inoculated
weak upper extremity pulses indicates __ dz
null value of difference is __
of ratio is __
C perfringens
viewable
watery diarrhea
toxin
arginine
shape
wound
Takayusa arteritis
0
1
Histamine binds H2 receptor to inc __ conc
Ach binds M3 receptor to inc __ conc
Gastrin also stimulates __ by binding CCkb receptors
this inc _ by K/H ATPase
systemic mastocytosis due to __ proliferation
mutation in __ RTK
w excessive release of __, pt gets syncope/flushing/pruritis, gastric ulcers
inhibits / enzymes leading to diarrhea
probenecid prolongs penicillin duration by inhibiting tubular __ secretion
GF released by __ are major cause of SMC migration./proliferation in atherosclerosis
stomach __ denatures proteins and activates pepsin that cleaves PP at aromatic AA locations
Panc/intestinal __ then degrade proteins to AA
parietal cells release __
also functions as __
removal needs long term __ supps and limiting size/sugars to stop dumping syndrome
cAMP
Ca
histamine
mast cell
KIT
histamine
pancreatic/intestinal
organic acid
PLATELETS
HCl proteases IF reservoir B12
w gastrectomy, / proteases are still able to digest protein
Lithium tox starts as __ then nonspecific neuro sx
when chronic, leads to A, C, T
assc w volume depletion or T__ that inc Na/Li reabsorption in PT
also w _, A, T, M
hair loss at anterior scalp/vertex has __
due to shortened __ growth phase
after placenta is delivered, hemostasis occurs via clotting/compression w __ contraction
MCC of postpartum hemorrhage is __
uterus fails to __ after delivery
__ is placenta that adheres to myometrium
due to _ tissue from prior surgery w absent decidua
prevents normal __ from villous tissue
diagnosed w prenatal care and tx w __ followed by hysterectomy
pancreatic/intestinal
GI sx
ataxia, confusion, tremors
thiazides
NSAIDs, ACEI, tetracyclines, metronidazole
androgenetic alopecia
anagen
myometrial
uterine atony
contract
placenta accreta
scar
separation
Csection
__ is painful prolonged uterine contractions, TENSE abdomen, vaginal bleeding
uterine rupture starts w intense __ and bleeding w fetal distress
palpated as __ in uterine wall
Nonneoplastic polyps H,I,J,S
Hyperplastic form /
Inflam seen in / w regenerating mucosa/inflam cells
Submucosal result of __ or lymphoid aggregates
Neoplastic includes S, V, T
larger __ correlates w malignancy, and __ are most likely to cause cancer
koilocyte indicates __
immature __ cell w dense, irregular cytolasm that looks like HALO
pyknotic nuclei looks like __
tropism for __ epithelium
placental abruption
pain
opening
hyperplastic, inflam, juvenile, submucosal
glands/crypts
UC/CD
lipomas
serrated, villous, tubular
size
VILLOUS
HPV
squamous
RAISIN
stratified squamous
__ is organism on smear that looks like cotton candy
incidental w __ use
Clue cells have __ to obscure margins
Glandular cells have __ cytoplasm w honeycomb clusters
transketolase converts R5P to __ intermediates
dx __ w low RBC transketolase activity that inc w TPP
ATN presents w inc / and normal ratio and oliguria
ischemia affects renal __ as well as PCT and __ LoH
these regions need __ for transport of ions
see __ of PT epithelial cells and loss of brush border
necrosis/denudement of __
high grade dysplasia involves __ aka CIS
low grade does not involve __
ellipsoid cysts w smooth walls and 2+ nuclei is __
tx w __
colonizes / mucosa w chronic diarrhea, malabsorption, flatulence
Mebendazole for A/E/A
Albendazole for E_
Actinomyces
IUD
rods
granular
glycolytic
WE
Serum creatinine, BUN medulla, THICK ASCENDING ATP flattening tubular basement membrane
entire epithelium
entire thickness
giardia
metro
Duodenum/jejunum
ascaris, enterobius, ancyclostoma
echinococcus
Spontaneous ICH in kids is due to __ malforms, ruptured berry aneurysm, or __ drug like cocaine
Berry aneurysm is particularly prone to rupture w __ due to HTN in proximal aortic arch
can have __ fracture due to excessive force transmitted through quad tendon
look for palpable gap in __
__ is abnorm in fibrinogen molecule
see excessive __ w high TT, PT, PTT
factor __ crosslinks fibrin to stabilize clots
sirolimus binds __ to inhibit mTOR
stops trxn of __ by preventing G1/S progression
__ reversibly inhibits IMP dehydrogenase for purin nucleotide synthesis
targets __ to dec B/T prolif and promote apoptosis
use __ to monitor heparin
arteriovenous, sympathomimetic
Coarctation of aorta
patellar
extension
dysfibrogenemia
bleeding
13
FK506BP
IL2
mycophenolate
lymphocytes
aPTT
anti- DNA topo 1 or __ indicates systemic sclerosis
keratoconjunctivitis sicca and xerostomia indicates __
see __ enlargement and inc risk of AI cx/NHL
antibodies are / and /
dx of ADHD requires sx before __ w greater than 6 sx in multiple setting
__ is severe/recurrent outbursts out of proportion to situation
occurs before __ and pt is constantly angry
tx w __ and AP
Scl 70
sjogren syndrome
parotid gland
SSa/Ro SSb/La
12
disruptive mood dysregulation do
10
CBT
