Thurs Wk 5 Mixed Flashcards
NNRTI do not require __ like NRTI
NRTI SE include L__ and lipodystrophy, HS rxn w __, pancreatitis w __ and bone marrow suppression w Z
NNRTI Se include __ like SJS, hepatotoxicity
Efavirenz is __
PI cause __ complications
oxidative injury to resp bronchioles activates alveolar __ to recruit PMNs
these release __ that overwhelm antiproteases
destroys __ and dilates airways in emphysema
__ is most common valvular disease predisposing to IE in developed countries
esp w __
leads to microscopic deposits of __ and fibrin w turbulent blood flow
can use D for AF rate control as opposed to BB/CCB
useful to inc __ tone to AV node
inhibits Na/K ATPase in vagal __ fibers to sensitize arterial baroreceptors
also enhances __ ganglion transmission to inc vagal output
phosphorylation lactic acidosis, abacavir, didanosine, ziduvidine rash teratogenic metabolic
macrophages
protesases
acinar wall
MVP
mitral regurgitation
platelets
digoxin
PNS
affarent
PNS
slowing AV node conduction still allows atria to __ but allows ventricles to contract normally
EF is AR deficiency in __
Fructose is __ sugar detected via copper reduction test
Aldolase B def is __ intolerance
prevents __/__
pineal gland mass has obstructive __ and parinaud syndrome
pupils will look __ w eyelid retration and near light dissociation
usually a G__ or midline
cerebellar tumor in kids is M__
see ATAXIA, TREMOR and ___
fibrillate
fructokinase
reducing
Fructose
glycogenolysis/gluconeogenesis
hydrocephalus
down
germinoma
medulloblastoma
nystagmus
LMS has ipsilateral paralysis of CN __///_
MMS has flaccid paralysis of __ w loss vibration/proprioception
SAH usually does not have __
may be assc w __ syndrome
Automaticity of SA node comes from inward slow __ Na channels (aka funny current)
T loop contains R, P, C to interact w ribosome
D loop of tRNA contains D__ to interact w tRNA
this, along w __ stem and anticodon facilitate correct tRNA recognition
net renal excretion is total __ rate minus total __ rate
TFR is equal to __ x plasma conc of substance
earliest sign of ESRD from diabetes is __ thickening and mesangial expansion
GBM has neg charge __ moities
DM causes release of __ to permit albumin leakage
5, 9, 10, 11
tongue
focal neuro signs
EDS
depolarizing
ribothymidine, pseudouridine, cytidine
dihydrouridine
acceptor
filtration, reabsorption
GFR
GBM
heparan sulfate
heparanase
initially in DM, hyper__ occurs w glomerular hypertrophy and inc GFR
then __ and HTN develops as GFR begins to fall
w __ nodules and proteinuria, nephrotic syndrome forms w very low GFR
WAXY CASTS MEANS __
subacute combined deg affects __ column, __/__ tracts
Poliomyelitis and WH assc damage to __
spinal cord hemisection is __ syndrome
see __ damage w flaccid paralysis at level of lesion
__ tract w spastic paralysis below lesion
__ column damage below
_ tract w loss pain/temp 1-2 levels below lesion
as move rostral in SC, white matter __ and section becomes oval
lower __ and lumbar areas have prominent __ horns for motor to extremities
look for __ horns of symp pregang neurons in THORACIC levels
CUNEATE FASCICULUS is only found above __
filtration
microalbuminuria
KW
CKD
dorsal, lateral ST, spinocerebellar
anterior horn cells
inc
cervical, anterior
lateral
T7
w aging, chest wall compliance __ due to stiffening of ribs
Lung compliance inc due to loss of elastic __
this is __
pt has __ RV due to lost recoil
TLC is __ as dec chest wall compliance balances inc lung complaince
FVC __ as RV inc
FEV1 and DLCO are __
CD31 found on __ cells and fxn in leuk migration (PECAM1)
ARSENIC, PVC, THOROTRAST leads to __
first ECG sign of MI is peaked _, followed by ST elevation and __ waves
ulcerated atherosclerotic plaque can produce __ MI
Transmural __ can be seen in Prizmental angina
large PDA can __ at anytime, leading to PHTN w sx of HF and Eisenmenger syndrome
see differential __/___ as O2 blood is delivered past LSCA
Pulses/BP will be ___
dec recoil homogenous inc normal dec dec
endothelial
hepatic angiosarcoma
T, Q
subendocardial
ISCHEMIA
reverse
cyanosis/clubbing
EQUAL
E coli genome has regulatory gene _, promoter _, operon _ and Z for __ and Y for __
this is __ mRNA which produces more than 1 protein
first line for RA is __
SE include oral/GI __ and alopecia, P__ and hepatotoxicity w PF
Bacteroides is gram __ anaerobe
use Azithromycin for C, M, H, M
LEGIONELLA is __ rod
__ is not effective in RA
DMARDs may take __ for effect in RA, thus tx w __/__ in short term
ToF caused by abnormal __ migration w anterior/cephalad DEVIATION OF INFUNDIBULAR SEPTUM
harsh murmur due to __ thus need inc SVR to force pulm blood flow
I, P, O, beta galactosidase, permease
polycistronic
MTX
ulcers, pancytopenia
neg
chlymidia, mycoplasma, Hib, moraxella
GRAM NEGATIVE
colchicine
weeks, NSAID/GC
NCC
RVOT
TAPVR has both pulm/systemic veins emptying into __
Coarctation is located J__
failed fusion of superior/inferior endocardial cushions is __ defect
in pt w coronary atheroscloerosis, concern for __ in kidneys
this releases __ and AT2, which constricts EA to maintain GFR
if pt is given __/__, EA dilates and GFR falls
VEGF stimulates __ in tissues w endothelial cell motitily and prolif
__ 2 is produced by cells involved in endothelial prolif, migration/differentiation
can help stimulate A__ prodxn
thus, important in E, H, and wound repair
__ in BM prevents new blood vessel formation
proinflam cytokines __/__ may cause indirect VEGF expression
right atrium
juxtaductal
atrioventricular septum
RAS
renin
ACEI/ARB
angiogenesis FGF angioblast embryonic development, hematopoeisis laminin
IL1, IFNG
MR causes inc left atrial __ and early/large v wave as LV ejects
can lead to __ and HF over time
loss dicrotic notch w rapid decline of aortic pressure in diastole and inc LV/aortic pressure indicates __
__ shown w very high LV pressure compared to aortic pressure
__ has high mitral pressures, that peak w kick just before valve closes
TR has early/large __ wave on RA pressure tracing
RH cath A wave is _ contraction (not present in AFIB)
C wave is __ contraction w closed TC valve
X is downward displacement of closed __ during ventricular eject (ABSENT IN TR)
V wave is RA __ against closed TC valve
Y- ventricular __ (prominent in constrictive pericarditis)
pressure
atrial fibrillation
AR
AS
MS
V
atrial contraction RV contraction TC vlave filling filling
Dx crypto w __ stain
or __ of CSF and culture on sabourad agar
is a __ form, thus no sporangia/mold is found
salmonella capsule has __ antigen
w vasoocclusive crisis causing __, salmonella can establish infection
adhesion to collagen allows for __ osteomyelitis
think __ in aspiration PNA w branching filaments/sulfur granules due to calcified mycelial fragments
appear yellow grossly, but __ on H&E
lower lobe consolidation w __ is present
tx w __
WK has oculomotor dysfxn w damage to CN / and vestibular nuclei
see horizontal nystagmus w bilateral __
ataxia due to damage to __
Memory/learning probs will __ due to damage to anterior/dorsomedial thalamus
India ink
latex agglutination
YEAST
Vi
bone necrosis
STAPH AUREUS
Actinomyces
basophilic
air bronchograms
PENICILLIN
3, 6
abducens palsy
cerebellum
persist
can reduce any MR w __ which dec afterload
Fxnal MR occurs w inc __ such as w acute hemodynamic changes
WBC casts in urine is always __
formed in tubules and precipitate w __ proteins
arterial vasodilators
preload
PYELONEPHRITIS
Tamm horstfall
