Saturday Wk 4 Mixed Flashcards

1
Q

type 4 collagen is present in ___
Type 2 collagen is C, V and N

Type 3 collagen is seen in Skin, lungs, intestives, blood vessels and G__ tissue of Spleen, LN, BM

0-4hrs after MI, __ happens
4-12 hrs, wavy fibers w narrow, elongated M__
12-24 hrs after hyperE__ w pyknotic sunken nuclei
1-3 days has C__ necrosis and predominant PMN infiltrate
3-7 days, disintegration of dead __/__
M__ infiltrate
7-10 days- phagocytosis of dead cells by__ w early formation of granulation tissue
2wks + has progressive __ deposition

A

basement membrane
cartilage, vitreous humor and nucleus pulposus

granulation

nothing
myocytes
eosinophilia
coagulative
PMN, myocytes
macros
macrophages
type 1 collagen
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2
Q
TCA overdose presents w Mental Status changes and S\_\_ w RDS
sinus tachycardia and H\_\_
Prolonged \_\_/\_\_ on ECG
arrhythmias and anticholinergic SE
due to blockage of fast \_\_ channels

wide QRS and ventricular arrhythmias need __ tx
this inc pH, favors the neutral drug preventing TCA from binding the __ channel

__ overdose has CNS depression w normal vitals
F__ is antidote

absence seizures are __ to stimulation
simple A__ present
easily provoked by H__
pt has no __ period

__ sequence is necessary for translation in eukaryotes
must have __ 3 bases upstream of start codon

A

seizures
hypotension
QRS, QT
Na

NaHCO3
fast sodium

benzo
flumenazil

unresponsive
automatisms
hyperventilation
post ictal

kozak
purine

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3
Q

__ and GTP is necessary to advance translocation

B thalassemia due to dec B globin chain __

IL1 is released by m__ for PMN/macrophage migration and sx of fever
Il 2 released by __ cells
inc T cells, as well as __/__ activity and B cell growth

IL6 is released by M__ to stimulate B/T cell growth
inc activity of O__ and acute phase reactants

__ is enzyme converting Glucose 1 phos to Galactose 1 phosphate using UDP
tx by switching to __ based formula

A

EF2

synthesis

macros
T cells
NK cells, macrophages

macros
osteoclasts

GALK
soy

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4
Q

Nonglucose monosaccharides G, M, F
only __ bypasses PFK, the RLS of glycolysis
Aldolase B then converts F1P to __ and ___
eventually forms G__ and shunted down glycolysis

MA serum has low _ and __ w inc pCO2
in DKA, CA works to __ HCO3 w protons
forms H2CO3 and dissociates into __/__
inside cells, CA then reforms H2CO3 and it breaks down to __/__
this HCO3 is transported across the basement membrane and into ___

Protons are highly __ by distal nephron H/K ATPase
kidneys then greatly inc __/__ secretion to act as buffer, combining w H+ to aid in absorption

A

Galatose, mannose, fructose
Fructose
DHAP, G3P
G3P

pH, HCO3
reabsorb
H2O, CO2
H, HCO3
circulation

excreted
NH3/H2PO4

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5
Q

Most physical sx of THC are __ and __

Arcuate nucleus releases D, G, G
Paraventricular nucleus releases A, C, T
Supraoptic releases A, O
Suprachiasmatic regulates the __

H/A/G inc gastric acid secretion
Prostaglandins __ secretion
__ is only one that promotes PC hyperplasia/rugal fold enlargement

M__ disease is excess prodxn of TGFA, which normally stimulates epithelial cell growth
causes hypo__ of parietal/chief cells w glandular atrophy/dec GA secretion

A

tachycardia, conjunctival injection

dopamine, GHRH, GnRH
ADH, CRH, TRH
ADH, oxytocin
circadian rhythm

histamine, Ach, gastrin
dec
Gastrin

Menetrier
plasia

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6
Q

infant w delayed motor development and flaccid paralysis has S__
caused by mutation in S__ gene for assembly of snRNPs in __ cells of lower motor neurons
cleave at __ site, and join to __ site on 3’ end

HBx enters host genomes to inc synthesis of __/__
may suppress __ and cell cycle regulation in host cells

__ tumors of ovary produce HCG

pelvic fracture w inability to void, blood at urethral meatus and boggy prostate indicate __ injury
most commonly occurs in __ urethra near membranous portion
prostatic is protected by _
straddle injury seen in B__ urethral segment
do not place __

A

spinal muscular atrophy
SMN1 gene
anterior horn
GU, AG

IGF2, IGF1 Receptor
p53

germ cell

urethral
posterior
prostate
bulbous
foley catheter
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7
Q

Pertuss is gram neg C__
P__ promotes adherence to the respiratory epithelium
cytotoxin allows tissue __
Pertussis toxin causes excess __ activity impairing phagocytosis and allowing survival

C__ is ability of lung/chest to expand in response to inc pressure
to compensate, obese indivs have high __ and reduced TV (rapid shallow breathing)
obesity is indicated w low __, thus reducing FRC
all other values should be __

comp of total myocardial ischemia is cessation of aerobic __ and initiation of anaerobic glycolysis
due to depletion of __, allowing toxic lactate to build
depletion leads to dec contractility w/in __
upon restoration of flow, myocardial __ results in dysfunction w contractility gradually returning

A

coccobacillus
pertactin
destruction
AC

compliance
RR
ERV
modestly low

glycolysis
ATP
seconds
stunning

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8
Q

AP can cause anti-__/__/__ SE

all mothers w HIV must have __ tx
avoid E__ in first 8 wks

P, X, O are alpha adrenergic agonists that constrict vessels of nasal mucosa
over time, leads to T__ w dec prodxn of NE from nerve terminals due to NF
known as rebound __ w vasodilation and exacerbation of sx

may use E__ as indirect adrenergic agonist
also assc w T__

PDA assc w metabolic __ and wide pulse pressures
may have signs of CV __

A

cholinergic/histaminergic/adrenergic

phentolamine, xylometalozaine, oxymetolazine
tachylplaxis
rhinorrhea

ephedrine
tachylplaxis

acidosis
strain

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9
Q

EPI ACTS ON __ More than __
NE acts on __ more than __

RIBAVIRIN inhibits __ in HCV

use __ in emergency tx of pt w CAD/ACS

testes derived from A__ connection in development, thus drain via __ LN

glans penis/clitoris drain in __ inguinal LN
majority of lymph (like scrotum) from lower body drains into __ inguinal LN

A

BETA, ALPHA
ALPHA, BETA

IMP DEHYDROGENASE

aortic
para-aortic

deep
superficial

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10
Q

first pharyngeal arch splits into __maxillary prominence and lower mandibular
fusion of 2 medial nasal prominences form the midline __ segment
this becomes P, 4 medial maxillary teeth, and primary __
L/R maxillary prominences fuse w MIS to form upper lip and primary __
if one prominence fails to fuse, __ cleft lip forms
if both fail to fuse, __ cleft lip forms

later, palatine __ grow medially to form secondary palate
thus fuses w __ palate, to form a complete palate
failure leads to cleft __

Pierre robin seq has M, posterior displacement of tongue, and U shaped __

A
Upper, lower
intermaxillary
philtrum, palate
palate
unilateral
bilateral

shelves
primary
palate

micrognathia, cleft palate

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11
Q

affarent limb of pupillary light reflex needs R, optic nerve, optic chiasm, optic _ and pretectal nucleus
defect known as __ pupil
this leads to __ probs as nasal portion of retina has more input to pretectal nucleus

Monocular scotoma due to partial lesion of R__ or optic disk or optic __
due to macular __ or ON

Right anopia is lesion of right __
such as w artery/vein __

Aneurysm of Acomm could cause __

Optic tract can be damaged w occlusion to anterior __ artery

Optic radiation damaged w occlusion of __ branch or lesion of posterior IC

A

retina, tract
Marcus Gunn
contralateral

retina, nerve
degeneration

optic nerve
occlusion

bitemporal hemianopsia

choroidal

MCA

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12
Q

__ aka cachetin promotes appetite suppression in hypothalamus and inc basal metabolic rate

w age, leftward bowing of the IV septum leads to dec in LV chamber __

normal ureters enter bladder at __ angle
bladder __ urethra as it fills to prevent retrograde flow
if ureter enters more perpendicular, __ can occur
this leads to chronic __
scarring occurs in upper/lower poles as compound papillae are always __
this leads to injury/dilation w loss of __ and secondary HTN

Posterior urethral valves are malformation of __ ducts, thus only present in males

A

TNFA

size

oblique
compresses
reflux
pyelonephritis
open
nephrons

wolffian

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13
Q

MCDK has ureteric bud that fails to induce metaneprhic __
nonfxnal kidney w cyst and __
if bilateral, presents w __ sequence

Bifurcation of __ before entering metanephric blastema leads to bifid ureter
high risk of __ reflux and uti

ARPKD is cystic dilation of __
assc w congenital __ fibrosis

Medullary cystic dz has tubulointerstitial __ and renal insufficiency
cannot __ urine
see S__ kidneys on ultrasound

A

mesenchyme
CT
Potter

ureteric bud
vesicoureteral

collecting system
hepatic

fibrosis
concentrate
shrunke

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