Friday Wk 6 Mixed 3 Flashcards

1
Q
use P\_\_ acetylcholinesterase inhib for MG
can have exacerbation if pt is undertreated, called \_\_ crisis
perform \_\_ test w Edrophonium
if it improvies sx, pt needs \_\_ dose
can have \_\_ crisis if dose is too high
muscles become \_\_ to impulse
Edrophonium does not _ sx
tx by \_\_ pyridostigamine for period

acute hemolytic transfusion rxn presents w F, chills, / pain and hemoglobinuria
due to __ incompat type 2 HS rxn
activation of / leads to vasodilation/shock
activation of __ leads to complement mediated hemolysis

allergic transfusion rxn has U and anphylaxis
due to __ mediated Type 1 response

__ has MAOI activity and can precipitate SS
used for /

A
physostigmine
mysathenic
tensilon
HIGHER
cholinergic
insensitive
improve
discontinuing

chest/back
ABO
C3a/C5a
MAC

urticaria
IgE

linezolid
VRE/MRSA

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2
Q

Power is detecting difference when __
depends on study __
Beta is a type _ error
aka rejecting null hypothesis when __

prefrontal cortex does not develop until __ decade, thus adolescents cannot weigh risks/benefits

admin __ after thyroid surgery if pt becomes hypocalcemic
Cinacalcet actives __ on Parathyroid gland to dec PTH release
used for pt w __

Demyelocycline is ADH __
calcium carbonate causes _ and is useful as phosphate binder

__ are GI hormones produced by gut to inc release of insulin
only respond to __ meals
thus, blood insulin levels are higher after __ of glucose

A

it is present
2
it is false

3rd

calcitriol
CaSR
secondary hyperPTH

antagonist

hypercalcemia

incretins
sugar containing
INTAKE

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3
Q

Estrogen inc __ activity while P dec BA secretion/emptying

look for cysts of //_ to indicate vHL disease
angiomas of face/leptomeninges indicates __

in MI, coronary __ can dilate to deliver collateral blood flow past blockage
avoid use of A/D as they vasodilate coronary arterioles in __ regions
this dec collateral blood supply aka coronary __ which worsens ischemia

can use these drugs to test for areas of __ that would otherwise not be seen

epicardial vessels are the large __ of heart

primary amenorrhea is also lack of _ in 13 YO w abnormal SSC

A

HMG CoA reductase

liver, kidney, pancreas
STURGE WEBER

arterioles
adenosine, dipyramidole
nonischemic
steal

occlusion

coronary arteries

menses

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4
Q

TS pt has variable __ dysgenesis
ovaries appear /
menstruation/breast development is __ dependent, thus these pt have none

atherosclerosis primarily affects A___
pulm vasculitis presents as __ pattern on CT

Pharyngoconjuctival fever has f, w cough, C/P/C due to Adenoirus
_ is fever w posterior pharyngeal vesicles

neonatal hepatitis w jaundice is classic for _ deficiency
__ disease is more common at young age

Gilbert dz is due to bilirubin __
Rotor is due to impaired __

A

ovarian
streak/fibrotic atrophied
ESTROGEN

arteries
interstitial

congestion, pharyngitis, conjunctivitis
HERPANGIA

A1AT
liver

overprodxn
uptake

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5
Q

alveolar hyperventilation causes __ mismatch that dec O2/CO2 exchange
can be P/P w hypoxemia stimulating chemoreceptors
blood flowing through O2 lung cannot take enough O2, thus inc __ gradient

dec compliance, upper airway obstruction, resp fatigue would __ PaCO2

portion of __ veins drain to RH via A/H veins
majority and thebesian veins drain to __

patency of __ after birth leads to LtR shunt and HF w volume overload
Bulbis cordis becomes __ portion of L/R venticle
Primitive atrium becomes __ portion of L/R atrium
Sinus venosus becomes __ portion of RA

A

VQ
PNA, pulmonary embolism
A-a

hypoventilation
inc

bronchiole
azygous, hemi-azygous
LA

DA
smooth
rough
smooth

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6
Q

PAH is pressure greater than __
often due to inactivating mutation in __ leads to smooth muscle prolif
second insult releases __ and dec NO/prostacyclin
leads to intimal / w inc PVR

gallbladder absorbs __ from bile
w hypomobility, can lead to biliary __ w formation of cholesterol stones
Brown stones due to __ enzyme
black stones due to /

azathioprine active metabolite is __

pt w epidural hematoma has loss/regain conciousness w _ interval
leads to __ decline in mental fxn
forms bw / dural layers
outer is adherent to __
restrained at _ bc dural layers are continuous here

gradual onset HA/confusion is __

A

25 mmHg
BMPR2
endothelin

WATER
sludge
b glucuronidase
HA, enterohepatic recirc

6TG

lucid
rapid
outer/inner
bone
sutures

subdural hematoma

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7
Q

bipolar 1 disorder occurs w/wout __ features
has manic features that occur __ mood sx

Vd is amount of drug given over __
ECF is around __ L w plasma only 3 L
drug enters __ and remains if it has high MW, bound to PP, or highly charged/hydrophilic
if drug has small mw, but hydrophilic, can enter __ fluid
if small MW and uncharged, can enter __ compartment w highest Vd

M/I is PDE3 inhib that prevents cAMP breakdown
thus used to inc cardiac __ and arterial/venous __
used for LV __ HF but avoid in hypoTN

__ lung cancer arises from basal cells in sheets/clusters w mitoses and scant cytoplasm
may have __ granules
__ carcinoma spreads along alveolar septae w papillary projections
__ differentiation w mucus prodxn is adenoca

A

psychotic
DURING

plasma concentration
14
plasma
interstital
intracellular

milrinirone, inamirone
INOTROPY, DILATION
systolic

SCLC
secretory
brochoalveolar

glandular

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8
Q

AI intrahepatic bile duct obs is __

hyperactivity of ML pathway assc w __ sx of schizo
low activity of MC assc w __ sx of schizo
use H/R to block D2 and dec positive sx of schizo

neurons in __ nucleus secrete Dopamine to bind D2 receptor and inhibit lactotrophes

CKD dec __ thus inc serum phosphate
this stimulates osteocytes/OC to release __ to dec PT phosphate reabsorption and calcitriol synthesis
this worsens __ but does not affect phos levels
w persistently high __, bone turnover leads to osteitis fibrosa

A

PBC

positive
negative
haloperidol/risperidone

arcuate

GFR
FGF23
hypocalcemia
PTH

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9
Q

uritcaria is due to inc __ of microvessels w edema of SUPERFICIAL DERMIS
involvement of deeper dermis/subq is __
epidermis is __ but dermis has inflam infiltrate

Acantholysis is separated __ in epidermis
seen in __
Acanthosis is thickened _
__ is premature keratinization of keratinocytes
strongly eosinophilic and seen in __
__ is epidermal edema that inc space bw cells

late peaking murmur in AS indicates ___

A

permeability
ANGIOEDEMA
normal

keratinocytes
PV
SS
dyskeratosis
SCC
spongiosis

more serious

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10
Q

spindle cells w glial processes and microcysts w rosenthal fibers in cerebellum is __

Medulloblastoma aka __ w HW rosettes and poor differentiated cells
Ependymomas usually occur in roof of __ in kids
pseudorosettes w _ positive stain

neuritic process neuropil is _
see small blue cell \_\_
NSE, chromo/synapto and \_\_ stains positive
high urine levels of _/_
marker is \_\_ on chromo 2

__ growing athero occlusion allows heart to develop anastamoses
higher risk of rupture w __ cap, lipid rich core
macros release __ to destabilize plaque
tx w __ to prevent destabilization

A

PA

PNET
4th ventricle
GFAP

neuroblastoma
tumor
S100
HVA/HMA
nMYC

SLOW
thin fibrous
MMP
statins

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11
Q

amatoxins are ingested and taken to liver to bind __ polymerase
stops prodxn of __
also affects organs w __ turnover
sx include ab pain, V, __ like diarrhea w blood/mucus
see acute / failure
test w urine __

Ricin inhibits eukaryotic __ subunit

PA CXR right heart border is __

endothelial injury releases __ for monocyte/T cell adherence
endothelium/leuks release __ to proliferate SMC that secrete ECM to form fibrous cap

Hashimoto thyroid has __ infiltrate w lymphs/PC
see __ centers and Hurthle cells
thyroid in Reidel dz is __ and fixed to surrounding structures

A
DNA dep RNA
mRNA
high cell
cholera
hepatic/renal
a amantins

60s

VCAMs
growth factors

lymphocytic
germinal
fibrotic

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12
Q

PTC has __ nodule on thyroid
tall crowed cells w scalloping of colloid indicates __ or tall cell PTC
__ thyroiditis has multinuclear giant cells
occurs after __ w painful gland

__ illness can precede GBS
__ in kids can lead to SB intussusception and SBO
Zika virus has __ rash w arthralgias and C__

vaccinated women provide transplacental IgG against __ to prevent neonatal hypertonicity
use antibiotics and __ to neutralize unbound toxin

A

enlarging
Graves dz
Subacute granulomatous
viral illness

viral
rotavirus
maculopapular
conjunctivitis

tetanus
immune globulin

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