Friday Wk 4 Mixed Flashcards
ToF 4 components
Hereditary Orotic aciduria has physical/mental retardation, M__ anemia and inc urinary OA levels
defect in __ synthase that catalyzes OA to UMP
thus, supplement w __
Receptors for T__ hormone and __ vitamins are located in the nucleus at all times
precursor mRNA is H__ RNA
P bodies are in the __ and are important in mRNA turnover/regulation
polyadenylate polymerase recognizes AAuAAA seq and then adds 250 __
VSD, OA, RVOT, RVH
megaloblastic
UMP
uridine
thyroid
fat soluble
heterogeneous nuclear
cytoplasm
adenines
SI joints in AS show erosions, S__ and narrowing w vertebral fusion
Class 1 HLA antigens on all _ cells and present to CD8
Class 2 HLA antigens on __ cells and present to CD4
include HLA D__/__/__
HDL can take cholesterol to liver via __ receptors SCARB1
or take cholesterol to __/__ receptors
very low levels inc risk for __
Colitis assc CRC occurs at \_\_ age lesions are \_\_ and nonpolypoid located more P\_\_ M\_\_ in nature mucinous or \_\_ ring cell that is poorly differentiated early mutation is \_\_ and late is \_\_
Sporadic CRC occurs at __ age
polyps that occur __
single tumor that is __ differentiated
early mutation is __ and late is __
sclerosis
nucleated
APC
DR, DP, DQ
scavenger
LDL/VLDL
cardiac events
younger flat proximal multifocal signet p53 APC
older
distal
well
APC, p53
MD is __ diverticula w mucosa/submucosa/muscularis affected
vitelline duct connects M to yolk sac until 7th week
Enterococcal endocarditis is most likely to cause __/__/__ infections
decision making capacity depends on pt ability to communicate the __
___ the info given
appreciate __ of decision
and give __ for decision
PCV13 is strep pneumo vaccine conjugated to __ toxin
HepB vaccine uses recombinant __ for vaccine
insert DNA into __ to produce desired antigen
true
midgut
UTI, intraabdominal, wound
choice
understand
consequences
reason
diptheria
surface protein
baker’s yeast
Potter facies is flat nose, recessed chin, prominent __ and low set ears
occurs w pulm __ and CV/limb defects
ADPKD due to mutation in PKD1 on chromo __ and PKD2 on chromo __
cysts occur __ in nephron, w microscopic cysts at birth
ARPKD shows dilated __ and collecting ducts
kidneys are __ at birth
MCKD has multiple cysts w absence of normal __ system
have ureteral or ureteropelvic A__ w nonfxnal kidney
blood products may have __ for anticoag
this can chelate __
stored RBC lose __ to solution, thus may cause hyperkalemia
epicanthal folds
16, 4
anywhere
distal tubules
enlarged
pelvocalicyeal
atresia
citrate
Ca
K
__ artery/vein lie anterior to the ureter
in females, gonadal vessels are __ to ureters
in males, testicular vessels pass into __ ring
ureter then lies ANTERIOR TO __ artery
uterine artery crosses __ ureter to reach uterus
piriform recesses are bounded medially by aryepiglottic folds and lterally by __ cartilage and thyrohyoid membrane
thin layer of mucosa covers __ laryngeal nerve, which provdes sensation above vocal cords
Affarent portion of __ reflex
affarent limb of gag is CN__
efferent limb is __
salivation triggered by CN __
passes through otic ganglion and into __ gland
gonadal
lateral
medial
internal iliac
over
thyroid
internal
cough
- CN 10
9
parotid
pt w positive Romberg has __ ataxia, usually from T__ affecting posterior column or B12 def affecting PN
pt w neg romberg has __ ataxia
rapid linear growth, oily skin, thick calvarium/prognathism due to __ overprodxn
GH acts on __ receptor
influences JAK/STAT for involvement in bone, cartilage, soft tissue __
perhilar alveolar __ and pleural effusion, w cephalization of pulm vessels all indicate __
may have cardiogenic edema w __ showing edema of interlobular septa
sensory
tabes dorsalis
cerebellar
GH
IGF1, growth
edema
ADHF
kerly B lines
brown pigment gallstones composed of Ca salts and unconj __
usually due to infection w E, A, C
releases enzyme __ to hydrolyze bilirubin
pigment stones also occur w high levels of __
D__ is CSCC enzyme, converting choelsterol to pregnenolone
Primary PAH is due to process that __ pulm vasculature aka vasculopathy
bilirunin
E coli, ascaris, clonorchis
beta glucuronidase
hemolytic anemia
desmolase
remodels
all rRNA except 5s rRNA is synthesized in the N__
IL1 is released from macros to stimulate __
__ angina occurs at rest/nighttime w ST elevation
can occur in __ vessels or w atherosclerotic plaques
Dihydroergotamine constricts __ via partial ag at A1 receptor, and serotoningergic receptors
other triggers include C, C, S
uncoupling protein in brown adipose tissue that returns protons to the matrix is T_
Flu like sx, new systolic murmur suggests infective _
may lead to deposition of __ in glomerular capillary wall, w resulting glomerulonephritis
leads to __ presentation such as DPGN
LM shows __ of capillaries
sub__ IgG/C3 deposition
IF is G__
nucleolus
helper t cells
prizmental
normal
vascular smooth muscle
cocaine, caffeine, smoking
thermogenin
endocarditis IC nephitic wire looping endothelial granular
pt w history of HF, presents w nonspecific GI/neuro manifestations then develops color vision problems likely has __ toxicity
Myelin is electrical insulator to inc conduction __ of AP
inc __ constant by reducing charge dissipation
reduces __ by dec capacitance (charge stored by membrane) and inc resistance (prevents dissipation)
thus, demyelination dec __ constant, and inc __ constant
summation can occur at D, C, and axon hillock, but not axon
Syndehaam chorea is caused by anti-strep antibodies directed against __ in brain
digoxin
velocity
length
time constant
length, time
dendrites, cell body
basal ganglia
methyoxyflurane SE is N__
Enflurane is a pro__
Benzocaine SE is M__
Osteochondroma is most common __ tumor in young males
bony exostosis w __ cap
Giant cell tumor occurs in E__ of long bones near knee
locally __ (osteoclastoma)
appears as S__
multinucleated giant cells that express __
nephrotox
convulsant
methemoglobinemia
benign
cartilaginous
epiphysis
aggressive
soap bubble
RNAKL
Osteosarcoma is \_\_ tumor B\_\_ distribution assc w \_\_ dz of bone, infarct radiation, L/F\_\_ syndromes see \_\_ triangle and sunburst pattern occurs in M\_\_ of long bones around knee
Ewing sarcoma appears in D\_\_ of long bones/pelvis/scapula anaplastic small \_\_ cell tumor Early \_\_ responsive to chemo \_\_ periosteal rxn in bone mutation is translocation \_\_ fusion of \_\_ and \_\_\_
malignant bimodal paget li fraumeni, familial retinoblastoma codman metaphysis
diaphysis blue metastasis onion skin 11, 22 EWS-FLI1
