Monday Wk 6 Mixed Flashcards
reversible injury characterized by mito __
irreversible injury shows mito __ and inc amorphous densities, as ATP cannot be produced
Myofibril __, disaggregation of __/__/__ elements, and TG accumulation w glycogen loss are reversible changes
Area postrema is located on dorsal __ at end of 4th ventricle
receives blood from _ vessels, thus it can sample many chemicals
__ defects due to failed fusion of neural plate
starts cervical and spreads /
failure to close rostral is _
failure to close caudal is __
AFP/AchE will be __
down syndrome AFP is __ and AChE is normal
GH acts on __ receptors to release IGF1 in liver
cytokines/GF also use __ pathway to stimulate trxn
swelling
vacuolization
relaxation, polysomes, granlar/fibrillar
medulla
fenestrated
neural tube
cranial/caudal
high
low
JAK-STAT
JAK-STAT
///ADH __ all use AC-GPCR transmission
__//_/ ADH __ all use IP3/DAG transmission
Risk of severe statin myopathy is inc w ___ that impair hepatic clearance
AN can lead to O, C, A w hypoTN/hypothermia/bradycardia
Tx w __ and nutritional rehab
O
tx BN w CBT/nutritional rehab and F__
Tx Binge eating disorder w L/T along w CBT/SSRI
avoidant/restrictive food intake is due to dislike of __ experience of eating
EHEC does not ferment __
does not produce G__
__ encoded, and better w iron deficiency
ACTH/TSH/PTH/V2
TRH/GnRH/AT2/V1
FIBRATES
osteoporosis, cardiac atrophy, arrhythmia
CBT
olanzapine
fluoxetine
lisdexamfetamine, topiramate
sensory
sorbitol
glucuronidase
phage
Edema factor Of B anthracis inc __ to cause edema/phagocyte dysfxn
Lethal factor prevents __ signaliing to cause disruption
B pertussis pertussis toxin __ AC w resulting phagocyte dysfxn
AC toxin acts as __ to cause phagocyte dysfxn
CO/HR is inc in __ w unchanged PaO2/PaCO2
changes occur in __
myopathy w cardiomyopathy and hypoketotic hypogly w low carnitine is __ def
cannot perform __ of FA, thus no ketone bodies formed
highly lipophilic drugs enter __ rapidly upon IV entry
then go to __ peripheral tissues like Liver, brain, heart, kidney
finally to __ vasc tissues Fat/Skeletal muscle
cAMP
protein kinase
disinhibits
AC
exercise
VENOUS BLOOD
Carnitine
b oxidation
plasma
well perfused
poorly vascularized
anemia inc release of __
Haptoglobin is __ in aplastic anemia (due to stem cell failure)
aplastic anemia triad: low __, T and absent __ cells
irregular uterine enlargement w pelvic pressure indicates __
Look for pressure to __ and constipation if located posterior
may require __ to relieve pressure
may have abnormal/prolonged __
can be on serosal surface () or in uterine wall () and below endometrium (_)
pelvic organ prolapse should not cause __
high fever w relative bradycarida, watery diarrhea and PNA like presentation is __
dx w __ antigen test
tx w __ or macrolide
Hib has P__ polysaccharide capsule
EPO
normal
Hb, thrombocytopenia, hematopoetic
leiomyomas colon splinting menstrual bleeding subserosal, intramural, submucosal
UTERINE ENLARGEMENT
legionella
urine
resp fluoroquinolones
polyribosylribositol phosphate
Staph aureus has __ to destroy RBC/WBC
5FU binds __ to inactive the enzyme
A__ is free rad scavenger that dec nephrotoxicity of chemo agents
common cancers w bone metastasis include PB KTL
degen arthritis should be relieved by __/__
mets are worse at __ w systemic sx and progressive pain
MMSE measures A/C but not executive fxn (draw a clock)
dementia requires impairment across __ domains w functional decline
alpha hemolysin
thymidylate synthase
amifostine
prostate, breast, kidney, thyroid, lung
rest/NSAIDs
night
attention/concentration
several
\_\_ nevi are found at D/E jxn FLAT, darker at \_\_ w preserved skin \_\_ nevi spread into dermis w some epidermal component appear \_\_ w uniform colon \_\_ nevi have lost epidermal component lose _ activity thus do not appear dark
cellular atypia that forms coalescing nests at D/E border is __
BCC has basaloid celss w __ arrangement of peripheral cells
__ has variable pigmentation, hyperkeratosis, and keratin containing cysts
chronic GC use can cause atrophy of __ 2 layers of AC
__ is greater than 10mmHg drop in SBP during inspiration
called __ sounds
w tamponade, __ of IV septum into LV leads to dec SBP and CO
also in severe / and C
Junctional center compound raised intradermal tyrosinase
melanoma
palisading
Seborrheic keratosis
pulsus paradoxus
korotkoff
bowing
asthma/COPD/constrictive pericarditis
some pts w resp sx/development of urticaria/anaphylaxis cannot tolerate __ to prevent MI
tx w __ to block ADP receptors instead
high altitude sickness due to __ hypoxia
lack of barometric __ dec pO2
tracheal O2 should be __
alveolar pO2 is __ due to mixing of tracheal pO2/venous CO2
diffusion in pulm capillaries is _ req only 1/3 of length to equilibrate
normally, diffusion depends on _ and if blocked, tracheal/alveolar pO2 will be equal
__ limited exchange occurs in Emphysema/PF as O2 cannot reach blood
__ is more soluble, and thus will appear normal
SCID pt may also have FtT and __
WAS due to impaired __ interaction of platelets/leuks
aspirin
Colpidigrel
hypobaric
pressure
150 104 quick PERFUSION DIFFUSION CO2
persistent diarrhea
actin cytoskeleton
use __ for cardiogenic shock
inc CO and dec LV __
be careful w __ as it causes mild vasodilation
be careful in pt w __ HF as it inc myocardial O2 consumption
S, R/B, B/O cancers all can cause rise in PTHrP in paraneoplastic process
called H__
Breast/MM known to cause __ w dec PTH/PTHrP/VD
__/__ can produce a matched VQ defect
LA develops from over __ and under __ of LA
problems w __ and liver are main cause
impaired rneal tubular bicarb reabsorption is __
can lead to __
dobutamine
filling pressures
hypoTN
decompensated
squamous cell, renal/bladder, breast/ovarian
humoral hypercalcemia of malignancy
osteolysis
atalectasis/consolidation
production, clearance
oxidative phosphorylation
proximal RTA type 2
AGAP metabolic acidosis
altered __ w impaired cough/gag reflex
dysphagia due to __ deficits
GERD/mech compromise of __
protracted __ and large volume enteral feedings all inc risk of __ pneumonia
PCP is P__
see __ behavior, dissociation, amnesia and __
LSD has __ hallucinations, E/D. tachy/HTN
Meth has ___ behavior w psychosis, tachy/HTN, __ movements and tooth decay
heroin overdose should have __ bowel sounds and low BP/HR/RR
Dermatitis herpetiformis has / at dermal papillae tip
occur symmetrically on __ surfaces, buttock/back
IgA antibody interacts w epidermal __
conciousness neuro swallowing vomiting aspiration
phencyclidine
violent, NYSTAGMUS
VISUAL, euphoria/dysphoria, choreiform
dec
fibrin/PMN
extensor
transglutaminase
use IVC filter or pt w contraindication to __
prevents propagation of __ from legs to lungs
phenytoin gingival hyperplasia due to __ exp
gingival macrophages stimulate gingival cells and alveolar __ to grow excessively
other SE include A/N due to cerebeullum/vestibular involvment
may have __ of facial features
SCD causes mutation in __ gene
thus, mutation is present in __
MCC of MS is __ w fibrous thickening and fusion of valve leaflets
may lead to atrial enlargement, atrial __ or Mural thromboses
degenerative calcium deposits on mitral valve occur in women over __
does not impair valve __
look for presence of __
anticoagulation
DVT
PDGF
bone
ataxia, nystagmus
coarsening
b globin
DNA
rheumatic fever
fibrillation
60
function
CALCIUM
think __ w friable vegetations on valve cusps
wavy fibers/elongated myoctes occur w/in __ hrs of MI
coag necrosis w lost / and PMN appear w/in 3 days
granulation tissue/neovascularization appears from _ to _ days
collagen is deposited after __
Sudden cardiac death 12 days after MI is due to ventricular __
macrophages are laden w degenerating myoglobin __ and hemosiderin
endocarditis
12
nuclei/striations
10-14
2 w
arrhythmias
pigment
