Tues Wk 6 Mixed 1 Flashcards

1
Q

ADH V2 activation inserts __ on apical cells of CCT
if ADH is low, aquaporin 2 returns to cytoplasm via __\
PT absorbs __/__ thus TF is isotonic
descending LoH, __ is absorbed thus fluid is hypertonic
thin Ascending LoH reabsorbs __ forming hypotonic fluid
DCT absorbs __ thus LOWEST OSMOLARITY is achieved
w ADH, collecting duct is __ to water and forms hypertonic urine
this is primary region of __ due to ADH water reabsorption

\_\_ dz due to inc volume/pressure of endolymph due to dec \_\_
damages _/_ components
triad of low freq \_\_ w fulnes
V\_\_ w NV
and \_\_ hearing loss

Acoustic neuroma causes __ sx of CN8

A
aquaporin 2
endocytosis
water/electrolytes
water
electrolytes
electrolytes
highly permeable
urine conc
meniere dz
reabsorption
vestibular/cochlear
tinnitus
vertigo
sensorineural

PERSISTENT

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2
Q

BPPV due to __ in semicicrular canal
brief vertigo due to __

Labrynithitis is inflam of _
single episode of __ lasting days

COPD results in chronic inflam via //_ cells
release __ to cause alveolar damage (E) and inc mucus secretion (CB) w impaired cilia fxn

__ body is denatured Hb
NADPH is necessary to __ glutathione via GR to protect against oxidative damage

__ disorder is violation of norms/rights of others before 18
becomes __ disorder after 18

stimulus control therapy for sleep dissociates bedroom from __
ie only use for __ purpose

A

otoliths
head movement

vertigo

PMN, macros, CD8
enzymes

heinz
reduce

conduct
antisocial

stimulation
SLEEP

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3
Q
Sleep hygiene maintains regular \_\_ w out naps
no \_\_ after lunch
limit A/S/E before bed
Relaxation use muscle \_\_ and breathing
Sleep restriction is bed only for \_\_
inc time in bed if sleep \_\_ high

lack of Hib vaccine leads to __ diseases

__ in aged cheese causes HTN emergency and SNS stimulation
usually metabolized in GI tract by __ which degrades other MA
Can use MAOI in pt w / depression but inc risk of SNS hyperactivity

A
schedule
caffeine
alcohol, smoking, exercise
contractions
sleep
efficiency

invasive

tyramine
monamine oxidase
atypical/tx resistant

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4
Q

1st pharyngeal pouch forms epithelium of _ and auditory tube, __ membrane, and epi of __
pharyngeal pouch 2 forms __ crypts
pharyngeal pouch 3 forms T and inferior parathyroid
Pharyngeal pouch 4 forms __ gland and ultimobranchial body

Kidney blood flow: _ arteries, arcuate arteries, _ arteries, AA, glomerular capillaries, __ arterioles, peritubular capillaries, interlobuar veins
as EA constriction inc past certain point, filtration of __ in GC inc capillary oncotic pressure
this can lead to __ GFR over time

Amphotercin b causes renal __ w dec GFR
can also be toxic w / and electrolyte disturbances
can switch to __ in pt who responds to amphotericin

A

middle ear, TM, external ear canal
palantine
thymus
superior parathyroid

interlobar, radial, efferent
plasma proteins
dec

vasoconstriction
ATN/DRTA
posaconazole

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5
Q

CN 7 exits skull via __ foramen
parotid gland tumors compress facial nerve leading to __
this indicates __ neoplasm

strabismus is deviation of __
due to abnorm in __

lung apex extends above __ and first rib
tension PTX dec __ to heart, thus dec CO

think __ artery injury w hoarseness due to close assc w RLN

IUS is smooth muscle innervated by __
SNS leads to __ while PNS leads to __
EUS is __ muscle
PNS also causes __ contraction to initiate micturation

A

stylomastoid
facial droop
malignant

eyes
EOM

clavicle
systemic venous return

inferior thyroid

ANS
contraction, relaxation
skeletal
detrusor

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6
Q

abrupt onset hematuria in pt w FH of SCD think __
due to obstruction of __ w ischemia
could be due to __ nephropathy, as NSAIDs dec RBF
may be due to __ w vasculopathy/hypoperfusion
P/UT __ can have edema that compresses vessels, leading to ischemia

see gray/yellow __ of distal 2/3 of pyramids due to coag necrosis
see scars as __ depressions form
sx due to sloughed __ w flank pain and dark urine

Fanconi syndrome triad _

Cornebacterium is gram _, _ positive, AEROBIC, and club shaped
has __ for Loffler medium

__ is breast mass in young women w well demarcated, painless, mobile mass
__ dependent, w myxoid stroma encircling glands

A
renal papillary necrosis
renal vessels
analgesic
DM
pyelonephritis, obstruction

necrosis
fibrous
papillae

hypophos, polyruria, acidosis

positive, catalase
metachromatic granules

fibroadenoma
estrogen

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7
Q

__ is malignant clonal cells surrounding an BM
myoepithelial layer is __

__ is ductal dilation w breast secretions and granulomatous inflam

__ carcinoma is vesicle, pleomorphic, cells w lymph infiltrate w pushing border

superficial DCIS spread to skin is __
__ adenosis is central acinar prolif w FIBROTIC tissue

Facial nerve is PNS to //_ salivary glands
somatic affarent of / in ear

__ is major RF for ARDS due to release of cytokines/enzymes w PMN __ to lungs
see hyaline membranes of _ and protein rich edema fluid w necrotic epithelial cells

pt w SIADH is __ due to release of natriuretic peptides
plasma osmo is __, urine osmo is __

A

DCIS
intact

mammary ectasia

medullary

Paget disease of breast
sclerosing

lacrimal, submandib, sublingual
pinna, external ear canal

pancreatitis
extravasation
fibrin exudate

euvoleic
low, HIGH

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8
Q

pt w PE has inflam, _ dysfxn and atalectasis of surrounding lung, which leads to worsening of RtL shunt

Tamoxifen/Raloxifene are __ inhibs of Estrogen binding

hypothalamic amenorrhea can occur w __ suppressing GnRH

__ and TF must bind promoter for trxn

in DM, nonenzymatic __ of proteins inc thickness/hyalinization and narrows arteries
leads to __ of endoneural arterioles w ischemic damage
IC __ occurs in PN, forming sorbitol
this leads to __ damage to axons/schwann cells

Autonomic PN leads to G/C, __ hypoTN and Urinary/sexual dysfxn
can have __ w bilateral involvement of Median/ulnar/common peroneal nerve

A

surfactant

competitive

excess excercise

RNA poly 2

glycosylation
microangiopathy
hyperglycemia
osmotic

gastroparesis, constipation, orthostatic
mononeuritis multiplex

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9
Q

Valproic acid blocks _ and inc _
Levetiracetem modulates /
Phenytoin/Valproate/Carb impair Na channels ability to recover from __

\_\_ is major morbidity/mortality cause of theophylline intox
also assc w \_\_
tx w \_\_ to dec GI absorption
use \_\_  to tx arrhythmias
use _/_ for seizures

inflam infiltrate in endoneurium is __
__ are seen as myelin is engulfed

high maternal glucose in utero leads to islet __ w transient hypoglycemia
fetal __ and CV anomalies
__ regression, RDS and P__ may develop

retained foreign bodies can lead to __ formation
__ is released by activated macros to active others

A

Na channels, GABA
GABA/glutamate
inactivation

seizure
arrhythmias
charcoal
BB
benzo/barbs

GBS
lipid laden macrophages

hyperplasia
macrosomia
caudal, plycythemia

granuloma
TNFa

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10
Q

GI sx w yellow tinting of objects is __ toxicity
__ eliminated, thus must reduce doses in elderly
__ may not rise, as it is derived from muscle, which is low in elderly

ectopic endometrium responds to __ w bleeding/shedding forming blood collections
w hemolysis/inflam, __ form to distort organ structure/fxn
thus can lead to _
in US ligament, lead to __ uterus

pt w endometrial hyperplasia has __ bleeding

Congenital __ has neonatal deafness, PDA, cataracts along w microcephaly

use IFNa for / virus, H_, C, and K

A

digoxin
renal
creatinine

hormones
adhesions
infertility
RETROFLEXED

intermenstrual

rubella

HepB/HepC, HCL, condyloma acuminata, kaposi sarcoma

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11
Q

cough SE in ACEI due to __/__ accumulation

__ is benign tumor of meningthelial cells of arachnoid
look for whorled __
found at F, P, lateral convexities
__ due to obstructed cortex and HA/N/V due to inc ICP

__ is suprasellar tumor w cord/nests of palisading squamous epithelium
looks like __ keratin

__ is paraventricular tumor w perivasc rosettes

__ is in cerebral hemi that crosses corpus callosum
see hypercellular area w bordering __ (pseudopalisading)

__ is cerebellar tumor w small blue cells and HW rosettes

A

bradykinin, substance P

meningioma
psamomma bodies
falcine, parasagittal
seizure
nausea/vomiting

craniopharyngioma
wet

ependymomas

glioblastoma
necrosis

medulloblastoma

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12
Q

__ tumor found in white matter w fried egg cells

__ is in cerebellum of kids
eosinophilic granular bodies w hair like __ fibers

spindle cells w palisading nuclei around __ bodies and eosinophilic Antoni A pattern is Schwannoma

think _ w goat hair exposure
spores ingested by alveolar macros and cause __ mediastinitis
sx include wide __ w bloody pleural effusion, septic shock, death
capsule is __
__ type org, w nonhemolysing adherent colonies
long chains look like __

Proteus has perticious __

A

oligodendrogliomas

pilocytic astrocytoma
rosenthal

verocay

B anthracis
hemorrhagic
mediastinum
anti-d glutamic acid
aerobic
medusa head

flagella

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13
Q

IL2 produced by __ to help grow CD4/CD8 and NK cells
thus, can use A__ for met melanoma/RCC to cause anti-tumor effect

__ is antiCD52 for CLL
cytotoxic to stimlate __ and ab dependent cell mediated cytotixicity

can use __ to inc MHC1/2 expression

IL1/IL6 are __ to promote fever

OSA leads to pulm __ w endothelial dysfxn and abnormal venous return due to SNS cardiac stimulation
lose __ variation in BP
systemic HTN due to high levels of __
also see SCD and __/arrhythmias

A

helper t cells
aldesleukin

Alemtuzumab
complement

IFNg

acute phase reactants

vasoconstriction
diurnal
NE
A fib

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14
Q

__ is MCC of spontaneous lobar hemorrhage
usually in / lobes
due to __ deposition walls of cerebral arteries w vessel weaking/rupture

brain __ seen in kids w intracranial hemorrhage

infarct strokes cause __ sx, while hemorrhagic strokes are persistent sx

__ is prog headache/NV w nonlocalizeable neuro sx like confusion
no evidence of __

A

cerebral amyloid angiopathy
occipital/parietal
B amyloid

AVM

waxing/waning

HTN encephalopathy
hemorrhage

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