Tues Wk 4 Mixed 2 Flashcards

1
Q
long term acclimatization leads to inc \_\_
\_\_ Hb prodxn due to EPO
\_\_ pulm diffusion capacity
VEGF induced \_\_
inc cellular \_\_

12-24 hrs after ischemic stroke, __ neuron develops
see __ cytoplasm, pyknotic nuclei, loss of __ substance

24-72 hrs, __ infiltration
3-7 days, M/M infiltration w phagocytosis

1-2 wks, reactive __ and vasc proliferation around necrotic area
begins __ necrosis

after 2 wks, __ scar forms

A
23 BPG
inc
inc
angiogenesis
mitochondria

red
eosinophilic
Nissl

PMN
monocyte, macrophage

gliosis
liquefactive

glial

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2
Q

excessive vitamin D leads to muscle __ w confusion, constipation, polyuria/polydipsia in hyperCa
renal stones form w bone __
granulomatous HyperCa can also be seen in / lymphoma

physical sx like HA/ab pain w nightmares upon separation has __ anxiety disorder

Adenosine deaminase converts adenosine to __
buildup is toxic to __

main SE of bile acid resin like C__ is high TG

A

weakness
demineralization
Hodgkin/nonhodgkin

separation

inosine
lymphocytes

cholestyramine

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3
Q

TGA is due to linear rather than __ development of aortiopulmonary septum
aorta is thus pushed __
L__ may be elevated due to poorly oxygenated blood

failure of __ produces syndactyly
failure of __ results in branchial celft cyst

__ portion of IV septum results from prolif of endocardial cushions
MCC of __

failed conotruncal __ results in TA w single arterial trunk

A

spiral
anteriorly
lactate

apoptosis
obliteration

membranous
VSD

septation

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4
Q

chronic cervical subluxation seen w neck __ and stiffness, w neuro findings
exacerbated by __ w compression of spinal cord/arteries
leads to __ paralysis w dec/absent reflexes below level
eventually becomes __ paralysis over time

most common viral meningitis is E, A (arthopod borne virus), H
Enterovirus includes C, E, P

viral meningitis protein is \_\_
glucose is \_\_/\_\_
WBC show \_\_ predominance
bacterial meningitis protein is \_\_
WBC are high w high \_\_
A

pain
intubation
flaccid
spastic

enterovirus, arbovirus, HSV2
coxsackievirus, echovirus, poliovirus

low
normal, high
lymphocyte
high
PMN
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5
Q

pt w hyperphenylalananimeia w elevated prolactin has __
can be due to def in cofactor __
converted from dihydrobiopterin via dihydrobiopterin __
Tyrosine becomes DOPA via tyosine hydroxylase ina rxn that also uses __ as cofactor

thus, pt will have normal phenylalanine levels upon correction of diet, but low __ w impaired CNS fxn

SSS presents w stensosis in subclavian artery __ to origin of vertebral artery
usually a result of A__
results in taking blood from __ vertebral artery away from brainstem
look for > __ mmHg BP difference in arms
reversal of blood flow occurs to the __ extremity

A

PKU
BH4
reductase
BH4

Dopamine

proximal
atherosclerosis
contralateral
15
affected
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6
Q

anti Jo1, anti M2, antisynthetase, antihelicase all indicate __
__ inflam infiltrate w CD8

LDOPA is rapidly metabolized in periphery via DOPA decarboxylase and __
COMT inhibs like E__ inc bioavailability by dec peripheral conversions

A__ enhances endogenous dopamine by inc synth and dec breakdown

Dopamine agonists include B, P, R

A

polymyositis
endomysial

COMT
entacapone

amantadine

bromocriptine, pramipexole, ropinirole

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