Monday Wk 7 Mixed Flashcards
claudication is due to fixed stenotic __ plaques
__ atherosclerosis can limit blood flow to internal pudendal arteries, making erection difficult
__ arteriolosclerosis is homogenous deposition of hyaline material in arteries/arterioles
osteolytic mets are more likely ___
ex include M, N, N, R, C
osteoblastic cancers are P, S, H
RCC originates from epithelium of __
cuboidal/polygonal cells w __ nuclei and abundant cytoplasm
Renal __ originates from COLLECTING DUCT CELLS
well differentiated eosinophilic cells w numerous __
__ is assc w RENAL PELVIS
tumor appears P__ w thin fibrovascular stalk
atheromatous
aortoiliac
hyaline
aggressive
MM, NHL, NSCLC, RCC, melanoma
Prostate, SCLC, HL
PT cells
eccentric
oncocytoma
mitochondria
transitional cell
papillary
wedge shaped hemorrhagic lesion at periphery of lung is __
hemorrhagic due to __ blood supply
Mycotic aneurysm is infectious aneurysm w destruction/dilation of __ wall
anaphylaxis has VD w _ and edema/tachycardia
upper airway edema and / w wheezing/bronchospasm
urticaria and __ w NV
tx IM __ and airway mx/fluids
type 1 HS rxn due to / degranulation
fluid goes from _ to _ space
high affinity IgE receptor on MC/basophils responds to crosslinking and __ following multivalent antigen binding
activates TK w __
acute transplant rejection has __ lymph infiltration of vessels, tubules, interstitum
calcineurin inhibs damage renal __ and tubule cells
look for arteriolar __ and tubule vacuoles
septic pulm emboli
dual
arterial
hypotension stridor, hoarseness pruritis EPINEPHRINE MC/basophil intravascular, extravascular
aggregation
degranulation
DIFFUSE
endothelial
hyalinization
arterial fibrinoid necrosis following transplant is __
PMN/necrotizing vasc is _
COX1 acetylation prevents __ in platelets
COX2 acetylation prevents __ prodxn in inflam cells
Acetominophen primarily acts on COX in __
not anti__ due to weak inhibition
serratus anterior rotates __ upward
above horizontal, / abduct shoulder
Erb palsy seen w damage to M/S w shoulder adduction, elbow extension, forearm pronation
acute onset diplopia in diabetic pt is __
only action via / pulls eye down/out
somatic fibers run __ while autonomic component outisde
thus, pupillary / is not affected
lacunar strokes affect __ CN 3
midbrain stroke affects __ CN3
hyperacute reject
acute cellular reject
TXA2
prostaglandin
CNS
inflammatory
SCAPULA
trapezius, serratus anterior
musculocutaneous, suprascapular
CN3 mononeuropathy
SO, LR
in core
size, reactivity
contralateral
both
pathogenesis of EOC is due to trauma/repair at __
such as N, I, P/E, L
prevented by M, O
__ medium kills off other contaminants
__ media identifies orgs based on metabolic/biochem properties
__ media includes special growth factors
__ media removes O2
pain in migraine due to activation of __ affarents in meninges
releases SP, CGRP causing neurogenic __ w vasdilation/pp extravasation
Triptan is / agonist
inhibits release of peptides, promoting __ and blocking pain pathways
avoid in pt w / dz
untx gonorrhea/chlymidia leads to P/E
pleural plaques occur in __ pleura
ovarian surface
nulliparity, infertility, PCOS, endometriosis, lynch
multiparity, OCP
selective
differential
enrichment
reducing
trigeminal inflammation 5HT1B/5HT1D vasoconstriction cardiac, cerebrovascular
prostatis, epidydmitis
esp use __ bridge w warfarin on pt w protein C def or w large loading dose
/ are depleted first in warfarin therapy
AML is inc __ on smear
translocates __ from c15 to __ on c17
CML translocates __ on c9 to c22
cuneus gyrus receives info from __ retina thus lower visual field
lingual gyrus receives info of __ retina thus upper visual fields
stroke of __ leads to loss of CN 5, 9, 10, 11 w Horner syndrome
rickets shows frontal __ w craniotabes, CC jxn widening w __
may see femoral/tibial __
XR of growth plates shows epiphyseal __ and cupping
EXCESS mineralized bone is __
HEPARIN
factor 7, protein C
promyelocytes
PML, RARa
ABL
upper
lower
PICA
bossing
rachitic rosary
bowing
widening
osteosarcoma
muscles lack __ thus must use G6P for glycolysis
no rise in blood lactate after exercise is __
Achondroplasia is mutation in __ gene
in __ bone formation, mesenchymal cells form chondrycytes to secrete cartilage matrix
form elongating cartilage templates that is _ and invaded by OB
deposition of __ forms woven bone and remodeled to compact bone
flat bones grow via __ ossification
mesenchymal cells form __ and osteoid matrix is secreted w cartilaginous bones
some NSCLC has inversion of c2 w fusion of __ gene
tx w __ in adenoca
cyclin D1 promotes G1/S __
Acute chest syndrome localizes to pulm __
spleen is brown due to __ w extravascular hemolysis
G6phosphatase
McArdle’s Dz
FGFR3
LONG endochondral
calcified
osteoid
intramembranous
OB
EMK-ALK
crizotinib
transition
vasculature
hemosiderinosis
cutaneous SV vasculitis due to drugs or __
think P, C, S, P, A
nonblanching palpable __ of LE
due to __ necrosis w PMN infiltration
__ has widened CT septa w PMN infiltration and fibrin exudation
see __ w septal fibrosis
superficial dermal edema w dilated lymph channels is _
Nystatin is not absorbed in _ thus only tx oral infections
pathogens HepB/C
penicillin, cephalosporin, sulfonamides, phenytoin, allopurinol
purpura
fibrinoid
EN
PMN
urticaria
GI tract
alveolar transmural pressure is always __ due to lung elasticity
chest wall result in __ transmural pressure except w maximal inspiration
oppose each other equally at __ w airway pressure of 0
intrapleural pressure is __ thus pulling air in
infiltrative dx of restrictive cardio may also cause _ w need for pacemaker
parasitic protozoa in heart w dense cell infiltrate/myofiber dysfxn is __ dz
cysts in ADPKD are __ w smooth border
do not __
can occur in any portion of _
tubular cell prolif w __ secretion
most common mutation in HFE on c6 is __
__ type receptors are ligand gated ion channels
Ach receptors have __ binding sites and only open when both bound
positive
negative
FRC
-5
bradycardia
Chagas
homogenous
enhance
nephron
fluid
C282Y
iontropic
2
A1/M1/M3 receptors are __ system
M2 is __ system
dilation of sinusoids/perivenular hemorrhage is due to __ obstruction in liver ie Budd Chiari Syndrome
mengiomas arise from __ cells at dural reflections of leptomeninges
well circum gray mass w calcification at white matter of brain is _
isoniazid requires specific protein sequence in enzyme __
this can have modified _ w resistance
PP is extension of __ neurons
solid, calcified, cystic component mass in brain is __
GPCR-Gq
GPCR-Gi
outflow
arachnoid
oligodendroglioma
target
binding site
hypophyseal
craniopharyngioma
Opsoclonus-myoclonus syndrome is __
arises from __ of AM/ganglia
firm ab mass w __ ecchymoses w anemia/pancytopeni
OM syndrome to _ response to CNS antigens
__ is malignant tumor in kids w HW rosettes
synaptophysin is glycoprotein in presynaptic vesicles of _, _, _ cells
GFAP positivity is seen in G, O, E, P due to astrocytes
meningiomas come from __ cells which are GFAP/synaptophysin neg
__ is CCB that can act on both vasc smooth muscle and cardiac myocytes
__ causes reflex tacchycardia and is useful in pt w bradycardia
neuroblastoma
NCC
periorbital
autoantibody
medulloblastoma
neurons, neuroendocrine, neuroectodermal
glioblastoma, oligodendroglioma, ependymoma, peripheral nerve sheath tumors
arachnoid
DILTIAZEM
Dihydropyridines
hypovolemia promotes __ reabsorption w acute gout attack
aldosterone inc / SECRETION w metabolic alkalosis
uric acid
H/K
