Wed Wk 6 Mixed 1 Flashcards
__ is common comp of SS
due to inc __ deposition in tissues w high monoclonal T cells secreting cytokines
earliest damage occurs in small __/__
eventually patient develops __
familial __ due to B globin gene mutation w dec binding of 23BPG
binding pocket contains __ charged AA (H/L) to bind negative 23BPG
HbH and Hb Barts have __ O2 affinity
\_\_ is cause of bacterial diarrhea that can go from domestic/farm animal to humans moves in \_\_ fashion also acquired via undercooked \_\_ look for diarrhea w T and leuks in stool pain may mimic \_\_
PAH
collagen
arterioles/capillaries
cor pulmonale
erythrocytosis
positive
extremely high
Campylobactr corkscrew food tenesmus appendicitis
__ can be transmitted FO by dirty hands/uncooked food or fomites
FHH has __/__ PTH but urinary calcium will be __
hyperthyroid may cause __ thus inc serum ca
w local back pain and FEVER, recent BACTEREMIA, must think __
usually spreads __ in adults due to bone w rich vascular marrow, corkscrew vessels
dx w blood cultures and __
only use invasive CT myelogram for pt who cannot use __
diuretics induce __ which should inc renin levels w use
ACEI/ARB should also inc _
thus if it stays low, pt __ has occurred
Measures plasma renin activity w amount of __ formed per unit time
PV bullae spread __ w pressure due to Ashboe-Hansen sign
antibodies against _ 1/3
see intraepithelial __ w detached keratinocytes, retained along BM w __ infiltrate
unaffected skin shows epidermal __/__ deposits
shigella
normal/high
low
VERTEBRAL OSTEOMYELITIS
hematogenosly
MRI
mri machiens
hypovolemia
RENIN
noncompliance
angiotensin 1
laterally desmoglein cleavage eosinophilic IgG/C3
bullae in BP are __ and Nikolsky sign is neg
__ is released by duodenal S cells in response to low duodenal pH
releases __ fluid from pancreas to neutralize acid
__ released by I cells of SI
__ released by D cells of pancreas/gut mucosa
__ inc insulin release and dec gastric acid release
released by __ cells of SI
__ released by M cells of SI
perform femoral nerve block at __ near lateral aspect of femoral artery
anesthestizes anterior T/F/K and saphenous nerve
runs bw / muscles
__ nerve runs in addctor hiatus of adductor magnus
FEMORAL CANAL ONLY CONTAINS __/__
serum Cl is __ in BN
tense
secretin bicarb rich CCK SS G1P K cells motilin
inguinal canal
thigh, femur, knee
psoas/iliacus
saphenous
lymphatics/LN
Low
__ binds warfarin in intestines to dec absorption
avoid __ w warfarin as it inc bleeding risk, and displaces warfarin from albumin
_ can interfere w VK metabolism/inhibit p450
p450 inhibitors A/N, A/A, A, C, C/G, vitamin E, O, __ hormone and S
p450 stimulators C, P, G, S, O, P, R
pol mutations in HIV cause resistance to __ as well as RTI
due to high __ rate of HIV
structure glycoproteins encoded by __ gene, and may evade the humoral immune response
Mycoplasma attaches to resp epithelium via __ that is also on PM of RBC
__ aggultination as they bind at low temperatures
Cholestyramine
NSAIDs
Acetominopen
aceto/NSAIDs, antibiotics/fungals, amiodarone, cimetidine, cranberry juice/ginseng, omeprazole, thyroid hormone, SSRI
carb/phenytoin, ginseng, St john wort, OCP, phenobarbitol, rifampin
protease inhibs
mutation
env
initiator caspases are number /
executioner caspases are _
w constant stumulation of __, T cells can undergo activation induced cell death
if mutation occurs w no apoptosis, inc autoreactive t cells leads to __ diseases
SCD has __/__ hemolysis
__ is common in young pt w SCD as bones contain hematopoeitc marrow
can be __ w pain crises or ulcerations
__ complex is primary infection into lower lobes and hilar LN
survives due to __ to inhibit alveolar macros
w fibrosis/calfcification, becomes __ compex
8/10
3/6
self antigens
AUTOIMMUNE
intra/extravascular
dactylitis
occlusive
Gohn complex
cord factor
Ranke
__ is nonselective B agonist
A1 receptors innervate __ to cause mydriasis
B2 receptors innvervate __ to cause tocolysis
pt w renovascular HTN needs __ to constrict EA and raise GFR
thus, avoid __ in pt w bilateral RAS
be careful w __ disease or decomp HF
normal creatinine can rise by __ over 2-5 days w ACEI
Heroin/pamidronate can lead to __
S/M/A/T can precipitate in renal tubules to cause failure
chronic interstital nephritis from L/C
drug induced tubular necrosis due to A/R/C/A/F
isopreterenol
pupillary dilator
uterus
AT2
ACEI
coronary atherosclerotic
30%
FSG
sulfonamides, MTX, acyclovir, triamterene
lithium/cyclosporine
aminoglycosides, radiocontrast, cisplatin, amphotericin B, foscarnt
intestinal ganglioneuromas in MEN2B present w __
performing __ can be life saving in MEN2B
NF2 has acoustic neuromas, brain __ and __ of dorsal root
CN V1, CN3/4/6 and superior opthalmic vein enter __
CN V2, infraorbital vessels, sphenopalantine ganglion enter __
CN V2 goes from FR to enter __ fossa to course into IOF
unstable angina is either , or inc in // or at rest
constipation
thyroidectomy
meningiomas, schwannomas
superior orbital fissure
inferior OF
pterygopalatine
new, freq, duration, intensity
inflam vasc sheating w hemorrhage in eye of HIV pt is always __
full thickness necrosis/edema replaced by atrophic __
due to __ spread to eye
greatest risk is __
use P_ as another tx for pneumocystis PNA
can use _ for prophylaxis
mesothelial cells line __ like pleural/peritoneal/pericardial
look for _ pleural effusion w thickening
histo shows long slender __ w TONOFILAMENTS
immune markers include __
sheets of uniform cells w salt/pepper pattern is __
__ in origin
ecological study analyses __
ecological fallacy is that it cannot make __ only assc
think esp __ design
nested case control studies participants who are followed to develop __ and become case
CMV retinitis
scar tissues
heme
retinal detachment
pentamide
Dapsone
body cavities
hemorrhagic
microvilli
pancytokeratin
carcinoids
NEUROENDOCRINE
population data
conclusions
MULTI COUNTRY
outcome
Classical condition has __ that causes pt to feel a certain way __ response
when paired w the __ stimulus, subsequent exposure can lead to __ response
in operant conditioning, positive actions __ punishment/reward
negative actions __ reward/punishment
pt w chron dz gets gallstones due to __ wasting
BA released by liver to enter __ w bile and emulsify fat droplets to aid in panc lipase breakdown
pass to __ and contact gut epithelium and aid in absorption of FA/glyceride/choelsterol
w damage to __ in CD, bile acids are lost in feces
get kidney stones due to inc __ absorption
unconditioned stimulus, unconditioned
conditioned, conditioned response
GIVE
REMOVE
bile acid duodenum jejunum terminal ileum OXALATE
AF due to aberrant electrical impulses w heightened atrial __ such as in pulm veins
can remodel __ w shortened refractory periods
AF has atria in chronic, continuous __
ventricular response depends on __ thus refractory period minimizes periods of contraction
Liver biosynthetic activity determined by /
transport/metabolic capacity by __
hepatocllular injury by /
cholestasis by /
cirrhosis can have thrombocytopenia/HSM due to __ of platelets
__ of inhaled anesthetic is minimum conc req to achieve anesthesia
partial pressure in __ equals pressure in other compartments
MAC is percentage of anestheic in __ that renders 50% unresponsive to stimuli
potency is _ proportional to MAC
MAC only depends on / as it is intrinsic to drug
excitability
AV node
depolarizations
Atrial conduction
PT/hypoalbuminemia bilirubin AST/ALT ALP/GGT splenic sequestration
potency brain inhaled gas INVERSELY age/body temperature
high AV conc gradient of inhaled anesthetic means more drug is taken up by __
thus has __ onset of action
BGPC corresponds to __
higher levels absorbed more by __ thus onset of action is higher
first dose __ occurs w ACEI as it cause hypoTN due to dec AT2
alongside __ volume depletion, renin is high to maintain AT2
thus, start dose __
PCWP should be similar to LA and __ pressures
Cardiac tamponade equalizes pressures in __ of ventricles/pulm artery
restrictive cardiomyopathy is __ dysfxn
peripheral tissues
sloweer
SOLUBILITY
blood
hypoTN
diuretic
low
LVED
diastole
diastolic
__ has intermediate sized lymphocytes w vacuolated basophilic cytoplasm
high number of __ that phagocytose debris
high /
cMYC is __ activator for cell prolif, differentiation and apoptosis
normal BP __ during inspiration less than 10 mmHg
hemothorax has __ to percussion
Burkitt lymphoma
macros
mitotic index/cell death
transcription
FALLS
dullness
