Wed Wk 5 Mixed 2 Flashcards
invasive __ develops in immunocompromised pt
forms granulomas, fever, chest pain and has predilection for __ thus spreaing hematogenously
tx w A__
wheezing/migratory pulm infiltrates indicates A__
influenza vaccine produces neutralizing antibodies against __ antigen to prevent entry
activated live viruses can stimulate __ thus generating CD8 t cells to kill infected cells
Neuraminidase claves __ residues allowing for release of influenza
O__ is sialyic acid analogue that competetively inhib neuraminidase
LE of elbow is attachment for ECRB/ED for wrist extension
see angiofibroblastic __ w no true inflammation
aspergillosis
blood vessels
amphotericin B
ABPA
hemagluttinin MHC class 1
sialic acid
oseltamivir
extensor carpi radialis brevis, extensor digitorum
overuse of __/__ leads to De Quervian tenosynovitis
round/polygonal cells w clear cytoplasm is __ from PT epithelial cells
lots of / give clear appearance on path specimen
DS due to inc gene __ effect
mosaicism is due to nondisjunction in __
DJS is AR disorder w defective hepatic __of bilirubin glucuronides due to mutation in MDRP2
develop __ bilirubinemia w black liver due to inc epinephrine metabs
tx Body dysmorphic disorder w __ and CBT
APL/APB
RCC
glycogen/lipids
dosage
mitosis
excretion
direct
SSRI
OSA due to relaxation of __ muscle tone
as O2 falls and CO2 rises, __ chemoreceptors trigger arousal
see daytime sleepiness and morning __ w cog impairment
CSA due to dec resp drive from __ disorder
assc w severe underlying __
OHS has chronic inc __ and dec __
HL has painless __ and B sx
LN biopsy shows __ cells w lymphs/histiocytes/eosinophils
__ syndrome is life threatening cx after drug exposure
seen w anticonvulsants C/P, allopurinol, sulfonmides, and antibiotics V, M
due to __ virus reactivation w clonal expansion of t cells
see F, LAN, facial edema and diffuse skin __
may damage L/K/L and labs show E w atypical lymphocytes and inc ALT
pharyngeal
carotid body/brain
HA
neuro
illness
PCO2, O2
LAD
RS
DRESS carbamazepine, phenytoin, vanc, minocycline Herpes rash liver, kidney, lung, eosinophilia
Drug induced ANCA vasculitis seen w P/M and H
chronic AV shunt inc CO due to inc __ stimulation
dec TPR and inc __ due to inc volume
this inc mean __
inc slope of VR/CO indicates __ TPR
proteins go from RER to Golgi via __ coated vesicles
SER fxns as __ in striated muscle
steroid producing cells of A/G/L have well developed SER
Ulnar nerve innervates __ portion of FDP
PTU, methimazole, hydralazine
SNS
venous return
systemic pressure
dec
COP2
sarcoplasmic reticulum
adrenals, liver, gonads
medial
__ regulates urea cycle by activating CPS1
OTC deficiency has excess __ and inc urinary orotic acid
pt has hyper_ w vomiting/confusion/tachypnea due to cerebral edema
leads to hyperventilation w resp __
CPS1 def leads to high __ but orotic acid is not inc
HIV pt w seizures/multiple ring enhancing lesions is __
can be transmitted via contaminated __
Aspergillus is assc w __
NADPH generates free rads w direct microbicidal activity and also activate granule __ to destroy pathogens
supine __ syndrome occurs when hypoTN, pallor, sweating occur in supine preg woman
due to uterus obstructing __ w dec preload/CO
preg has expanded plasma __ and inc RBC mass w low __
N-acetylglutamate carbamoyl phosphate ammonemia alkalosis ammonia
toxoplasmosis
food
NEUTROPENIA
proteases
hypoTN
IVC
volume, BP
SCLC stain for __ markers like NCAM/CD56, enolase, chromogranin, synaptophysin
may have neurosecretory __
inferior MI assc w __ due to blocked SA/AV node
can tx w __ to block vagal influence on heart
SE is __ w narrowed anteiror chamber angle/dec outflow of AH
can lead to acute __
will tx U__
use O_ Anticholinergic to tx spastic bladder
__ deletion seen in CF
AGAP MA due to ketoacids that bind and dec serum __
should have compensatory resp __ by hyperventilating, thus CO2 should be low
if higher than expected, must have hypercarbic __
neuroendocrine
granules
bradycardia atropine myrdiasis glaucoma uveitis
oxybutinin
phenylalanine
HCO3
alkalosis
RF
Met acidosis comp- pCO2= 1.5 (serum bicarb) + __ +/-2
Met alk- pCO2 should rise__ for every 1 dec in HCO3
low Estrogen inc release of __/__ cytokines and RANKL, which leads to osteoporosis
antags are reversible w __ bond and irreversible w __ bond
in noncompetitive antags, ED50 is __ but efficacy is reduced
regular insulin forms __ due to H bonds bw C termini of B chains and hexamers w __ ions
O2 blood from placenta enters fetus via __
__ is remnant in adult
then goes to liver and bypasses via __ into IVC
goes to heart, and delivered to __/__ circs
into aorta, blood is passed to _ and deoxy blood goes to placenta via umbilical __
SVC drains only __ blood from head/UE
8
.7
IL1/TNFA
ionic, covalent
inc
dimers
Zn
umbilical vein ligamentum teres DV pulm/systemic tissues artery deoxygenated
CN 9 is motor to __ muscle in elevating larynx while swallowing
PNS through __ nucleus to CN9 and otic ganglion/auriculotemporal nerve for __ gland sec
Sensory to __ and eustachian tube, tonsils, upper __ and carotid body/sinus
superior salivatory nucleus of __ nerve causes secretion by submandibular/sublingual glands via submandibular ganglion
Naloxone is antag of __ opioid receptors
reverses analgesia, sedation hypotn and __
completely inactivated by __ so must be given parentarally
mu receptor for dependence, euphoria, __/__ depression, dec GI __ w sedation
Kappa for __ and sedation
delta has __ effects
stylopharyngeus
inferior salivatory
parotid
TM, pharynx
Facial nerve
mu
RD
liver
resp/cardiac
motility
miosis
antidepressant
__ participate in CNS tissue repair and compensate for lost neuron volume
originate in N__ w round, nuclei, small bodies, contain glial fibrils w __
aid in repair, structural __ and BBB and __ properties
O_ come from neuroectoderm
small nuceli w pale __
produce __
M__ are monocytes in BM
fxn in __
Fibroblast migration aids in injury repair of __
ketone bodies in DKA result in __ serum bicarb
plasma osmolarity is __
insulin causes __ shift of bicarb
Nmen penetrates CNS at cerebral capillary __ surface
astrocytes
neuroectoderm
GFAP
support, metabolic
oligodendrocytes
halo
myelin
microglial cells
phagocytosis
PNS
inc
high
intracellular
endothelial
aneurysm of Acom can cause bilateral __
unilateral homonyous hemianopia due to occlusion of __ artery in optic tract
or occulusion of MCA/posterior limb of __
hemorrhage into pituitary is __ dx
due to preexisting __
severe HA, bitemporal __ and opthalmoplegia
tx w __ first to prevent hypoTN
leads to __ due to adrenocortical insufficiency
click of MVP due to tensing __
due to malaligned __
w inc preload/afterload, normal arrangement is seen and dec __ is heard
Primary is due to __ degen of CT of MV/CT
may have proliferated __ of valve, fragmented elastin, inc __ and type 3 collagen
hemianopsia
anterior choroidal
internal capsule
pituitary apoplexy adenoma hemianopsia GC cardiovascular collapse
chordae tendinae valves murmur myxomatous spongiosa, mucopolysaccharides
Sacral micturation center located at __
responsible for bladder __
PNS fibers from ventral white matter stimulate __ receptors on bladder wall
Pontine micturation center found in __
helps to relax __ w bladder contraction upon voiding
Cerebral cortex __ SMC
In NPH, expanded ventricles block __ and cannot communicate bw cortexSMC
thus pt has __ incontinence
S2-S4 contraction cholinergic reticular formation EUS inhibits
corona radiata
urge
Osteo__ have single nucleus and come from mesenchymal stem cells
Osteoclasts originate from __ and have multinucleated mature cells
need __ and RANKL for differentiation
OPG is __ receptor to prevent RANKL/RANK interaction
loss of OPG fxn leads to __ PDB
IGF1 inc __ replication/collagen synthesis and dec collagen degredation by dec __
blasts
monocytes
MCSF
decoy
juvenile
osteoblast
MMP
