Syndrome of inappropriate ADH (SIADH) Flashcards

1
Q

What happens to someone with this syndrome

A

excessive ADH secretion in the absence of hypovolemia or hyperosmolality b

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2
Q

Can it be acute or chronic

A

both

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3
Q

Why does it happen

A

the negative feedback system of the hypothalamus isnt working

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4
Q

What are some causes that relate more to acute SIADH

A

surgery
stress
temperature changes
and possibly drugs that increase ADH production or act on the renal tubules

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5
Q

What are some causes that relate to chronic

A

Tumors of the brain and lungs
CNS disorders
advanced TB
HIV

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6
Q

What are the mani’s

A

dilutional hyponatremia
decreased urine output despite adequate or increased intake
urine osmolarity is high while serum osmo is low
decreased levels of serum sodium, hematocrit, and BUN levels

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7
Q

What is the severity of the symptoms dependent on

A

degree of sodium depletion and water intoxication

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8
Q

What are the treatments

A

in mild case- fluid restriction
if fluid restriction isn’t enought: diuretics and lithium
sever cases of water intox: patient gets a hypertonic sodium chloride solution of 3%

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9
Q

Biggest difference between SIADH and DI

A

SIADH is low vs DI is high levels of urine

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