Renal infections: Acute Pyelonephritis Flashcards
What is acute pyelonephritis?
Infection of one/ both upper urinary tracts
Who does acute pyelonephritis usually affect?
Women
What is the etiology of Acute Pyelonephritis
E coli, Proteus, Pseudomonas
What is the pathophysiology of acute pyelonephritis
Usu from lower urinary tract or via the blood supply
Infection –> infiltration of WBCs with inflammation, edema and purulent urine
Does it cause renal failure?
Rarely, usually no
What are the two types of acute pyelo
Uncomplicated and complicated
What is uncomplicated?
occurs in healthy young women without structural or urinary tract obstructions
What is complicated?
Occurs in children or adult with structural or functional urinary tract abnormalities
What factors contribute to the development of complicated acute pyelo
cauterization, Outflow obstruction, urinary instrumentation, pregnancy, vesicoureteral reflux, neurogenic bladder
What is the onset of acute pyelonephritis
abrupt with shaking chills, moderate to high fever, flank/ groin pain
What are lower urinary tract symptoms?
dysuria, frequency and urgency, malaise, looks & feels ill, nausea and vomiting with abdominal pail
What is the treatment for acute pyelo
Antimicrobial drugs
2-3 weeks of antibiotics
Who are the people affected most?
Very young & older adults
