Repair vs Resolution Flashcards
What does resolution usually involve
minimal necrosis of parenchymal cells
returns to nearly 100% structure and function
What is lost during repair
loss of some function
What partially replaces the parenchymal cells
scar tissue
Why would repair happen instead of resolution
because their was too much damage to the parenchymal cells and the Extracelllular matrix
What does the term regeneration refer too
Replacement of lost parenchymal cells by division of adjacent surviving parenchymal cells
What is regeneration dependent on
the regenerative capacity of involved cells (ie, their ability to divide), (2) the number of surviving viable cells, and (3) the presence Extracellular matrix and how much it can aid the healing process
What are some things the ECM brings to the site of injury
growth factors
How does the ECM aid the healing process
helps regulate cell proliferation
differentiation
provides a foundation for cell adhesion
