Hypoxia Flashcards
1
Q
What is hypoxia
A
deprivation of oxygen to cells
2
Q
Which cells are the most effected by hypoxia
A
highly oxygen dependent cells like brain, heart and kidney cells
3
Q
What are some ways hypoxia happens
A
low oxygen % in the air
ichemia
respiratory disease
anemia
4
Q
What is an important indicator of cell injury and death
A
intracellular enzymes leaking into the extracellular fliud
5
Q
Can laboratories pick up these enzymes
A
yes
6
Q
What does hypoxia do to the cell
A
without oxygen, anaerobic metabolism ramps up, building up lactic acid which drop pH which cause denaturing effects, also with less or no ATP produced the energy dependent Na/K membrane pump can’t work properly so NA and K aren’t balance in/out of the cell causing water and ions to build up in the cell
