Cystic Fibrosis Flashcards
In CF where is the mutation
chromosome 7
What is decreased in Cystic Fibrosis?
decrease in water and sodium in respiratory trac
What is a result of CF bacteria buildup?
Pneumonia
Respiratory Failure
What is the treatment for CF?
No cure, just to ease and reduce complications
Antiboitics to stop lung infections
antiinflam drugs for airways
administration of oral pancreatic enzymes
What happens in the lung with CF?
person is unable to expire, causing build up secretion - end up with thick mucus, mucus clogs the airways and traps bacteria
What are some digestive signs
thick mucus blocks tubes that carry digestive enzymes from your pancreas to your small intestine causing S Smelly stool I Intestinal blockage (meconium ileus) P Poor weight gain and growth S Severe constipation
Can the signs of CF be delayed
yes
What is a symptom of CF involving sweat
salty sweat
What are some respiratory signs
L lung infections
E exercise intolerance
T thick sticky mucus
What does the CFTR do
create channels on the cell surface to allow the movement of chloride (a component of salt) in and out of the cell.
What happens in CF relating to the CFTR
the CFTR is either malformed or missing causing an imbalance of chloride ions in and out of cells
who is most effected
caucasians, 1 in 2500 to 3500
What are some ways CF is diagnosed
newborn screening
genetic and sweat test
What is the most common cause of death from CF
Pneumonia
Respiratory Failure
