Pulmonary Malignancies

Question 1

What are the different types of Non- Small Cell Lung Cancer?

Answer 1

Squamous cell carcinomas, adenocarcinomas, large cell carcinomas

Question 2

What are the growths of squamous, adenocarcinoma, and large cell?

Answer 2

Squamous: slow growth
Adenocarcinoma: moderate growth
Large cell: rapid growth

Question 3

Who is most likely to be affected with squamous cell carcinoma

Answer 3

Men and smokers

Question 4

Where is squamous cell usually found

Answer 4

Originates in central bronchi then to major bronchi and adjacent intrapulmonary lymph nodes

Question 5

What is frequent in squamous cell

Answer 5

Central cavitation

Question 6

What is the most common subtype of lung cancer in North America

Answer 6

Adenocarcinoma

Question 7

Who is most likely to be affected in Adenocarcinoma

Answer 7

women and nonsmokers

Question 8

What is adenocarcinoma

Answer 8

Malignant epithelial cell tumor with glandular differentiation or mucin production by the tumor cells

Question 9

Where is adenocarcinoma usually found

Answer 9

located more peripheral in X-rays and associated with pleural fibrosis and scarring

Question 10

Does adenocarcinoma have a poorer prognosis than squamous cell?

Answer 10

Yes

Question 11

What are large cell carcinomas

Answer 11

Large, polygonal cells

group of neoplasms that are anapestic and difficult to categorize as squamous or adenocarcinoma

Question 12

Where is large cell usually found

Answer 12

periphery of lung, invades bronchi and larger airways

Question 13

Does large cell have a poor prognosis

Answer 13

Yes because they tend to spread to distant sites early

Question 14

What is the etiology of pulmonary malignancies?

Answer 14

Smoking and genetic mutated stem cells

Question 15

What are the manifestations of pulmonary malignancies?

Answer 15

Cough
Hemoptysis
Chest Pain
Recurrent pneumonia
Bronchitis

Question 16

How does small cell lung cancer grow?

Answer 16

Very rapidly

Question 17

How is small cell lung cancer characterized

Answer 17

small round to oval cells, size of a lymphocyte

Question 18

Where are the tumors in small cell thought to arise from

Answer 18

Neuroendocrine cells of the bronchial epithelium, may secrete hormonally active products

Question 19

How does one get small cell

Answer 19

cigarette smoking

Question 20

All types of lung cancers have what

Answer 20

can synthesize bioactive products and produce paraneoplastic syndrome

Question 21

Where are the most common sites of these metastases

Answer 21

Brain, bone, liver

Question 22

How do you make a diagnosis of lung cancer?

Answer 22

History & physical exam, chest radiography, bronchoscopy, Pap test of sputum, percutaneous needle biopsy

Question 23

What are the treatments of NSCLC

Answer 23

surgery (lobectomy, pneumonectomy, segmental resection of the lung), radiation therapy, systemic chemo

Question 24

What are the treatments for SCLC

Answer 24

Chemo and radiation