Disorders of Skeletal Muscle Flashcards
1
Q
What are contractures
A
Permanent shortening of a muscle of joint, may develop secondary to scar tissue contraction in the flexor tissues of a joint
2
Q
What is muscular dystrophy (MD)
A
Muscle weakness and muscle loss
3
Q
When do forms of MD appear
A
Sometimes in infancy/ childhood but could me until middle age or later
4
Q
What are the different types of MD
A
Duchene (DMD)
Fascioscapularhumeral (FSH)
Limb-girdle (LG)
Motonic dystrophy (MyD)
5
Q
What is the cause of Duchene
A
inheirited X-linked trait
6
Q
Who are more severely and commonly affected
A
males
7
Q
What is mutated in Duchene
A
dystrophin
8
Q
What is dystrophin
A
a large protein
9
Q
What is patho of the Duchene
A
skeletal muscle degenerates and is replaced with fats and connective tissue
10
Q
What are the manifestations of Duchene
A
muscle weakness causing frequent falls pseudohypertrophy of the calf frequent respiratory infections scoliosis cardiomyopathy increased creatine kinase in serum
