reg renal blood flow and the GFR- neural and humoral control mechs

Question 1

Normal perfusion of blood per minute in adults in the kidneys

Answer 1

1000 to 1300 mL

Question 2

Whats the points of this blood flow

Answer 2

to maintain GFR for waste removal more than the metabolic needs of the kidney

Question 3

What percent of cardiac output is 1000-1300 mL

Answer 3

20-25%

Question 4

What portion of the kidney does the sympathetic sys affect

Answer 4

the afferent and efferent arterioles

Question 5

What does increased sympathetic sys activity cause

Answer 5

vasoconstriction

Question 6

When might you see intense sympathetic stimulation

Answer 6

shock or trauma

Question 7

How would sympathetic stim affect the blood flow and GFR

Answer 7

they would decrease because of the vasoconstrition

Question 8

What are some humoral substances that can cause vasoconstrition of renal vessels

Answer 8

ADH, angiotensin II, and endothelins

Question 9

What are some substances that can cause vasodialation

Answer 9

dopamine
nitric oxide
prostaglandins E2 and I2

Question 10

Under certain surcumstances what might decrease blood flow and GFR through inhibiting prostaglandins

Answer 10

aspirin and NSAIDS

Question 11

Why might aspirins and NSAIDS have this effect on blood flow and GFR

Answer 11

prostaglandins are thought to protect the vasoconstricting efffects of sympathetic stimulation and angiotensin II