Exam 4: Lecture 49: Acid-base Flashcards

1
Q

Are acids of bases H+ donors

A

acids

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2
Q

Are acids of bases H+ acceptors

A

bases

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3
Q

Do acids of bases give up an OH- group in a soultion

A

bases

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4
Q

Do strong or weak acids dissociate completly in a solution

A

strong acids

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5
Q

Do strong or weak acids dissociate only partially in a solution

A

weak

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6
Q

Is carbonic acid a strong or weak acid

A

weak

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7
Q

Is HCl and NaOH a strong or weak acid

A

strong

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8
Q

What is the range for physiological pH

A

7.35 to 7.45

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9
Q

What is the holy grail of acid-base

A

H+

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10
Q

What happens to the following when small changes in pH can produce major disturbances in physiology

  • enzyme function
  • membrane potential
  • hormones
A
  • most enzymes function within a very narrow pH range
  • membrane potential may be altered and usually becomes less negative (depolarize)
  • hormones become less effective
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11
Q

What controled pH and is tightly controlled

A

Homeostasis

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12
Q

What is the range for blood pH

A

7.35 to 7.45

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13
Q

What is the lowest and highest pH can get before death occurs due to everything shutting down and the body goes into a coma/death

A

less than 6.8
greater than 8.0

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14
Q

Below 7.35

acidosis or alkalosis

A

acidosis
- acidemia

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15
Q

Above 7.45

acidosis or alkalosis

A

alkalosis
- alkalemia

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16
Q

Are acids or bases taken in with foods

A

acids

17
Q

Are acids or bases produced by metabolism of lipids and proteins

A

acids

18
Q

CO2 and H2O use what enzyme to make carbonic acid (H2CO3)

A

carbonic anhydrase

19
Q

What enzyme is important in CO2 hydration Equation

A

Carbonic anhydrase

20
Q

What is the name of this equation

pH = pKa + log10 [A-]/[HA]

A

Henderson - Hasselbalch Equation

21
Q

What is the main ion that is a volatile acid in the lung

A

CO2-

22
Q

What are fixed acids from the kidneys that are non-volatile?

A

phosphoric acids
sulfuric acid
lactic acid
keto-acids

23
Q

What is a non-volatile fixed acid that comes from protein breakdown

A

phosphoric acid

24
Q

What is a non-volatile fixed acid that comes from ischemia and hypoxia breakdown

A

lactic acid

25
Q

What is a non-volatile fixed acid that comes from disease (diabetes)

A

keto-acids