Exam 2: Lecture 19 and 20 (I screwed this up) Flashcards
What type of inotropic effect is described as
- increase in ejection fraction
- increase stroke volume and cardiac output for a given end-diastolic volume
positive inotropic effect
What type of inotropic effect is described as
- decrease stroke volume and cardiac output for a given end-diastolic volume
- decrease ejection fraction
Negative inotropic effect
Why type of inotropic effect is described as
- decrease stretch
negative inotropic effect
What type of inotropic effect is described as
- giving fluids to animals
- stretch in ventricles
positive inotropic effect
What point on the graph descibes
- end of diastole
1
What point on the graph descibes
- left ventricle filled with blood from left atrium - end diastolic volume
- 140 mL
1
What point on the graph descibes
- venticular muscle is relaxed
- ventricle is relaxed = activates = contracts = ventricular pressure increases
1-2
What point on the graph descibes
- all valves are closed
- ventricular volume is constant
- isovolumeteric contraction
1-2
What point on the graph descibes
- ventricular pressure becomes quite high
2
What point on the graph descibes
- left ventricular pressure is higher than aortic pressure
- aortic valve opens
- blood ejected rapidly due to pressure
2-3
What point on the graph descibes
- left ventricle pressure reamins high beacuse it is still contracting
- left ventricle pressure decreases as blood moves from left ventricle to aorta
2-3
What point on the graph descibes
- blood left in the left ventricle
- end diastolic volume
- 70 mL
3
What point on the graph descibes
- systole ends
3-4
What point on the graph descibes
- ventricles relax
- ventricular pressure decreases below aortic valve and they (aortia valves) close
3-4
What point on the graph descibes
- ventricular volume remains the same (isovolumetric)
- 70 mL
- All valves are closed
3-4
What point on the graph descibes
- ventricular pressure fallen below left atrial pressure
- mitral (AV) valve opens
- left ventricle fills with blood from left atrium passively
4-1
What point on the graph descibes
- atrial contraction
- left ventricular volume increases back to end-diasoltic volume
- 140 mL
4-1
What point on the graph descibes
- ventricular muscle relaxed
- pressure increases slightly as the compliant ventricles fill with blood
4-1
what effect causes
- venous return increases
- increase in end-diastolic volume
- increase in stroke volume
- afterload and contracality stay constant
increased preload
- end diastolic volume
what effect causes
- increase in aortic pressure in the ventriclar cycle
- eject blood against greater than normal pressure
- left ventricle pressure is greater than normal
increased afterload
what effect causes
- decrease blood ejected from ventricles during systole
- decrease stroke volume
- end-diastolic volume increases
increased afterload
what effect causes
- if more of the concentration is spent in isovolumetric contraction to match the higher afterload
- the less of the contraction is leftover and is available for ejection of the stroke volume
increased afterload
what effect causes
- ventricles can develop greater tension and pressure during systole and eject a larger volume of blood than normal
- end systolic volume decreases
increases contractility on the ventricular cycle
what is needed when you have an increase in work of the heart, increased activity to make sure the heart is healthy and determines HR
increased myocardial oxygen consumption
When you are sick what happens to oxygen consumption
increase in more consumption of myocardial oxygen consumption to increase force
What is the main determinant of myocardial oxygen consumption
heart rate
What causes the following
- decrease signals in the body
- hytrophy
- increase in muscle
- increase in ventricular wall tension
decrease in blood flow
what happens in block A
isovolumetric ventricular contraction