Week 9 - Adaptive Immunity Flashcards
1
Q
Adaptive Immunity Diagram
A
2
Q
What are the 2 types of adaptive immunity?
A
- Antibody Mediated (humoral)
- Cell Mediated
3
Q
What occurs in antibody mediated adaptive immunity?
A
- B-Lymphocytes produce antibodies and with the help of T Lymphocytes, generate interactions for antibodies to neutralize, eliminate, or destroy foreign antigens
4
Q
What is antibody mediated immunity responsible for?
A
- body’s response to invading bacteria and viruses
5
Q
Which cells are involved in the humoral response? (2)
A
- Plasma and Memory B cells
6
Q
Antibody Mediated Process diagram*
A
7
Q
What are the antibodies/immunoglobulins secreted by B Lymphocytes? (5)
A
- IgG
- IgD
- IgM
- IgA
- IgE
8
Q
What is IgG? (2)
A
- largest amount of circulating antibodies
- heavily expressed on 2nd+ exposure to antigen
9
Q
What is IgD?
A
- Acts as a B-cell antigen receptor
10
Q
What is IgM?
A
- FIRST antibody produced from plasma cell with 1st exposure/immune response
If low exposure or tested too early
11
Q
What is IgA? (2)
A
- Secretory antibody that is present in high concentrations in the secretions of mucous membranes and the intestinal mucosa
- Prevents infection in the upper and lower respiratory tracts, GI tract, and GU tract
Basically traps foreign materials
12
Q
What is IgE? (2)
A
- Associated with hypersensitivity reactions
- forms a receptor on masts cells ana basophils and triggers histamine release during allergic reactions
So it attaches to mast cells on 2nd exposure, where mast cells release proinflammatory action
13
Q
Which cells are included for cellular mediated immunity? (5)
A
- T-lymphocytes
- Cytotoxic T cells
- Helper T cells
- Regulatory T cells
- Natural Killers
14
Q
What do T cells do?
A
- major role in regulating antibody mediated immunity and innate immunity
15
Q
What do cytotoxic T cells do?
A
- Destroy self cells infected by parasites
