Week 6 - Types of Tissue + Lethal Cell Injury Flashcards
1
Q
What are the 4 types of tissue?
A
- muscle
- neural
- connective
- epithelial
2
Q
What is the concept overview of tissue integrity for this unit?
A
- emphasizes structurally intact and physiological functioning epithelial tissues, such as the integument (skin and subcutaneous tissue) and mucous membranes
3
Q
Scope of tissue integrity diagram
A
4
Q
What are the causes of lethal cell injury? (6)
A
1.cellular ischemia (lack of O2)
2. Physical damage - heat, cold, radiation, electrothermal, mechanical
3. Microbial injury
4. Immunological injury - damage caused by body’s own immune system
5. Normal substances with unintended contact (ex. gastric acid leads into abdominal cavity)
6. Neoplastic growth (benign or caner)
5
Q
What is necrosis? (2)
A
- uncontrollable passive pathological process of cell death
- occurs when cells are exposed to extreme conditions
6
Q
What does necrosis do to a cell? (2)
A
- causes cells to swell and rupture
- leads to inflammation and damage of surrounding tissue
7
Q
What is coagulative necrosis? (3)
A
- caused by ischemia
- free radical
- still looks like cell for a while
8
Q
What is liquefactive necrosis? (2)
A
- caused by the body releasing enzymes to kill bacteria
- causes damage (liquefy) of neighbouring cells (eg. abcess)
9
Q
What is caseous necrosis? (3)
A
- a distinctive form coagulative necrosis where tissue no longer recognizable
- cheese-like appearance
- caused by mycobacterial infections (tuberculosis) or tumour necrosis
10
Q
What is gangrene? (2)
A
- build up of decomposing dead tissue
- usually refers to appendage/limb with ischemic necrosis (slow drop in O2)
11
Q
What is dry gangrene? (3)
A
- chronic/slow
- caused by degenerative diseases (atherosclerosis, diabetes)
- may auto-amputate
12
Q
What is wet gangrene? (2)
A
- acute/quick
- caused by sudden elimination of blood flow (severe burn or traumatic crush injury), or possible bacteria
