Week 7 - Folic Acid Deficiency Anemia Flashcards
1
Q
What is folate? How about folic acid? (2)
A
- folate is the natural vitamin
- folic acid is the synthetic supplement
2
Q
What does folic acid deficiency cause? (3)
A
- impaired DNA formation
- results in larger than normal cells
- these abnormalities target the cell for early destruction
3
Q
What causes folic acid deficiency anemia? (3, 4)
A
- poor nutrition, especially a diet low in leafy vegetables, liver, citrus, dried beans and nuts
- uncommon in US and Canada due to fortified foods - Can also be intestinal malabsorption caused by conditions that affect the gut, such as Crohn’s disease
- Medications can lead to folic acid deficiency (oral contraceptives)
4
Q
What are the signs and symptoms of folic acid deficiency anemia? (6)
A
- jaundice
- pallor
- fatigue
- weight loss
- serum Hgb and Hct decreased
- serum folate decreased
5
Q
Long term use of folic acid can cause ____
A
cancer (increased risk)
6
Q
Do you need to change your diet when taking folic acid?
A
- yes, or treatment of underlying condition to improve absorption of folate
7
Q
When is folic acid activated?
A
- folic acid is inactive when administered and activated in the body
8
Q
How and when is folic acid administered? (2)
A
- orally as a supplement
- short term only
